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Revision as of 20:20, 10 February 2025
Keiko Ozato
Keiko Ozato, Ph.D.
| Nationality | Japanese-American |
|---|---|
| Known for | Research on interferons and chromatin |
Keiko Ozato is a prominent Japanese-American immunologist and molecular biologist known for her pioneering research in the fields of interferon biology and chromatin regulation. She has made significant contributions to our understanding of how the immune system responds to viral infections and how gene expression is regulated in immune cells.
Early Life and Education
Keiko Ozato was born in Japan and pursued her undergraduate studies at Kyoto University, where she developed an interest in molecular biology. She later moved to the United States to continue her education and research.
Career
Dr. Ozato joined the National Institutes of Health (NIH) in the United States, where she has spent the majority of her career. At the NIH, she has held various positions, including Senior Investigator at the National Institute of Child Health and Human Development (NICHD).
Research Contributions
Dr. Ozato's research has focused on the role of interferons in the immune response. Interferons are proteins that are crucial for the defense against viral infections. Her work has elucidated the mechanisms by which interferons activate immune cells and regulate the expression of genes involved in the immune response.
One of her notable contributions is the discovery of the role of BRD4, a member of the BET family of proteins, in regulating chromatin structure and gene expression. Her research demonstrated how BRD4 interacts with acetylated histones to facilitate transcriptional activation, which is critical for the rapid response of immune cells to pathogens.
Awards and Honors
Dr. Ozato has received numerous awards for her contributions to science, including the NIH Director's Award and the American Association of Immunologists Lifetime Achievement Award. She is also a member of several prestigious scientific societies.
Personal Life
Dr. Ozato is known for her dedication to mentoring young scientists and promoting diversity in the scientific community. She has been an advocate for women in science and has worked to create opportunities for underrepresented groups in biomedical research.
