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Revision as of 15:42, 10 February 2025
Drug Expiration
Drug expiration refers to the date after which a medication is not guaranteed to be safe or effective. This date is determined by the drug manufacturer and is typically printed on the packaging of the drug.
Overview
The concept of drug expiration dates emerged in the 1970s in the United States, following a mandate by the Food and Drug Administration (FDA). This mandate required drug manufacturers to provide evidence of the effectiveness and safety of their products over a specific period of time. The expiration date is the final day that the manufacturer guarantees the full potency and safety of the medication.
Determining Expiration Dates
Drug expiration dates are determined through stability testing. Stability testing involves assessing the drug under various conditions, including temperature, humidity, and light exposure. The drug is considered stable if it retains 90% of its original potency. The time it takes for the drug to lose 10% of its potency under these conditions is used to calculate the expiration date.
Implications of Using Expired Drugs
While some expired drugs may not be harmful, they can lose their effectiveness over time. This can be particularly dangerous for life-saving medications, such as epinephrine for allergic reactions, or nitroglycerin for heart conditions. In some cases, expired drugs can become toxic or cause adverse reactions.
Storage and Disposal
Proper storage can help to extend the shelf life of medications. Most drugs should be stored in a cool, dry place, away from light. Some medications, such as certain antibiotics and insulin, may need to be refrigerated.
Expired or unwanted medications should be disposed of properly to prevent accidental ingestion or environmental contamination. Many pharmacies and local waste facilities offer drug take-back programs.
See Also
