Cadexomer iodine

Cadexomer Iodine

Cadexomer iodine is a topical antimicrobial agent used in the treatment of chronic wounds, such as venous leg ulcers, pressure ulcers, and diabetic foot ulcers. It is a complex of iodine with a polysaccharide-based carrier, which allows for the slow release of iodine over time, providing sustained antimicrobial activity.

Mechanism of Action

Cadexomer iodine works by releasing iodine slowly when it comes into contact with wound exudate. The iodine acts as a broad-spectrum antimicrobial agent, effective against a wide range of bacteria, fungi, and viruses. The slow release of iodine helps to maintain an effective concentration of the antimicrobial agent in the wound bed, reducing the risk of infection and promoting healing.

Indications

Cadexomer iodine is indicated for use in:

• Chronic wounds
• Venous leg ulcers
• Pressure ulcers
• Diabetic foot ulcers

Contraindications

Cadexomer iodine should not be used in patients with known sensitivity to iodine or in those with thyroid disorders, as iodine can be absorbed systemically. It is also contraindicated in pregnant or lactating women and in children under the age of 12.

Application

Cadexomer iodine is typically applied as a gel or ointment directly to the wound bed. The area should be cleaned and dried before application. The frequency of dressing changes depends on the amount of exudate and the condition of the wound, but it is generally recommended to change the dressing every 2 to 3 days.

Side Effects

Common side effects include local irritation, itching, and redness at the site of application. Systemic absorption of iodine can lead to thyroid dysfunction, although this is rare.

Clinical Studies

Clinical studies have demonstrated the efficacy of cadexomer iodine in reducing bacterial load and promoting healing in chronic wounds. It has been shown to be particularly effective in wounds with high levels of exudate.

Also see

• Iodine
• Antimicrobial agents
• Wound care
• Chronic wound management

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