OR2S2: Difference between revisions

OR2S2
Symbol	OR2S2
HGNC ID	15000
Alternative symbols	–
Entrez Gene	–
OMIM	–
RefSeq	–
UniProt	–
Chromosome	1q44.2
Locus supplementary data	–

Latest revision as of 20:38, 30 December 2024

OR2S2 is a gene that encodes a member of the olfactory receptor family of proteins. These receptors are involved in the detection of odor molecules and are a part of the G-protein-coupled receptor (GPCR) superfamily.

Function[edit]

Olfactory receptors, such as those encoded by the OR2S2 gene, are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor proteins are characterized by a 7-transmembrane domain structure, which is also shared by many neurotransmitter and hormone receptors.

Gene Family[edit]

The olfactory receptor gene family is the largest in the human genome. The OR2S2 gene is one of many that contribute to the diversity of olfactory receptors, allowing humans to detect a wide range of smells.

Location[edit]

The OR2S2 gene is located on the long arm (q) of chromosome 1, specifically at band 44.2. This location is part of a cluster of olfactory receptor genes.

Clinical Significance[edit]

While the primary function of OR2S2 is related to olfaction, variations in olfactory receptor genes can sometimes be associated with differences in smell perception among individuals. However, specific clinical conditions directly linked to OR2S2 have not been extensively documented.

Research[edit]

Research into olfactory receptors like OR2S2 continues to explore their role in the sensory system and potential implications in other physiological processes. Understanding these receptors can provide insights into the mechanisms of smell and its impact on behavior and health.

References[edit]

External Links[edit]

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-'''OR2S2''' is a gene that encodes the olfactory receptor, family 2, subfamily S, member 2 protein in humans. The [[olfactory receptor]] proteins are members of a large family of G-protein coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome.
-== Function ==
+{{Infobox gene
+| name = OR2S2
+| symbol = OR2S2
+| HGNCid = 15000
+| chromosome = 1
+| arm = q
+| band = 44.2
+}}
-The protein encoded by the OR2S2 gene is an [[olfactory receptor]], a type of G protein-coupled receptor that is involved in the detection of smell. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein coupled receptors (GPCR) arising from single coding-exon genes.
+'''OR2S2''' is a gene that encodes a member of the olfactory receptor family of proteins. These receptors are involved in the detection of odor molecules and are a part of the G-protein-coupled receptor (GPCR) superfamily.
-== Gene ==
+==Function==
+Olfactory receptors, such as those encoded by the '''[[OR2S2]]''' gene, are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor proteins are characterized by a 7-transmembrane domain structure, which is also shared by many neurotransmitter and hormone receptors.
-The OR2S2 gene is located on the long (q) arm of [[chromosome 11]] at position 15.4. More precisely, the OR2S2 gene is located from base pair 34,378,879 to base pair 34,380,062 on chromosome 11.
+==Gene Family==
+The olfactory receptor gene family is the largest in the human genome. The '''OR2S2''' gene is one of many that contribute to the diversity of olfactory receptors, allowing humans to detect a wide range of smells.
-== Clinical significance ==
+==Location==
+The '''OR2S2''' gene is located on the long arm (q) of [[chromosome 1]], specifically at band 44.2. This location is part of a cluster of olfactory receptor genes.
-While the specific function and clinical significance of OR2S2 is not yet fully understood, olfactory receptors in general are known to play a role in a wide range of physiological processes. They are involved in the detection of smell, but also in various other functions such as the regulation of [[appetite]] and [[metabolism]], and the detection of environmental hazards. Mutations in olfactory receptor genes have been associated with various diseases, including [[congenital anosmia]] (inability to smell), [[obesity]], and certain types of [[cancer]].
+==Clinical Significance==
+While the primary function of '''OR2S2''' is related to olfaction, variations in olfactory receptor genes can sometimes be associated with differences in smell perception among individuals. However, specific clinical conditions directly linked to '''OR2S2''' have not been extensively documented.
-[[File:OR2S2 gene location on human chromosome 11.png|thumb|right|300px|Location of the OR2S2 gene on chromosome 11.]]
+==Research==
+Research into olfactory receptors like '''OR2S2''' continues to explore their role in the sensory system and potential implications in other physiological processes. Understanding these receptors can provide insights into the mechanisms of smell and its impact on behavior and health.
-== See also ==
+==See Also==
 * [[Olfactory receptor]]
-* [[G protein-coupled receptor]]
+* [[G-protein-coupled receptor]]
-* [[Chromosome 11 (human)]]
+* [[Chromosome 1]]
-== References ==
+==References==
+{{Reflist}}
-{{Reflist}}
+==External Links==
+* [https://www.ncbi.nlm.nih.gov/gene/OR2S2 NCBI Gene: OR2S2]
+* [https://www.genecards.org/cgi-bin/carddisp.pl?gene=OR2S2 GeneCards: OR2S2]
-[[Category:Genes on human chromosome 11]]
+[[Category:Genes on human chromosome 1]]
 [[Category:Olfactory receptors]]
 [[Category:G protein-coupled receptors]]
-{{medicine-stub}}