Enteroinvasive Escherichia coli: Difference between revisions
CSV import |
CSV import |
||
| Line 1: | Line 1: | ||
{{Infobox medical condition | |||
| name = Enteroinvasive Escherichia coli | |||
| synonyms = EIEC | |||
| field = [[Infectious disease]] | |||
| symptoms = [[Diarrhea]], [[fever]], [[abdominal pain]], [[dysentery]] | |||
| complications = [[Dehydration]], [[hemolytic uremic syndrome]] | |||
| onset = 1-3 days after exposure | |||
| duration = 5-7 days | |||
| causes = [[Escherichia coli]] (EIEC) | |||
| risks = [[Contaminated food]], [[contaminated water]], [[poor sanitation]] | |||
| diagnosis = [[Stool culture]], [[polymerase chain reaction]] (PCR) | |||
| differential = [[Shigellosis]], [[Salmonellosis]], [[Campylobacteriosis]] | |||
| prevention = [[Hand washing]], [[safe food handling]], [[clean water supply]] | |||
| treatment = [[Rehydration therapy]], [[antibiotics]] in severe cases | |||
| medication = [[Ciprofloxacin]], [[Azithromycin]] | |||
| prognosis = Generally good with treatment | |||
| frequency = Rare in developed countries | |||
}} | |||
'''Enteroinvasive Escherichia coli''' ('''EIEC''') is a type of pathogenic [[bacteria]] that is closely related to [[Shigella]] species in genetic and pathogenic terms. EIEC is one of the six recognized categories of diarrheagenic ''[[Escherichia coli]]''. | '''Enteroinvasive Escherichia coli''' ('''EIEC''') is a type of pathogenic [[bacteria]] that is closely related to [[Shigella]] species in genetic and pathogenic terms. EIEC is one of the six recognized categories of diarrheagenic ''[[Escherichia coli]]''. | ||
==Characteristics== | ==Characteristics== | ||
EIEC strains are characterized by their ability to invade [[epithelial cells]] of the [[colon]], causing a disease similar to [[Shigellosis]]. The primary symptoms of EIEC infection include [[diarrhea]], abdominal cramps, and fever. | EIEC strains are characterized by their ability to invade [[epithelial cells]] of the [[colon]], causing a disease similar to [[Shigellosis]]. The primary symptoms of EIEC infection include [[diarrhea]], abdominal cramps, and fever. | ||
==Pathogenesis== | ==Pathogenesis== | ||
EIEC pathogenesis involves the invasion and destruction of the [[intestinal epithelium]]. The bacteria penetrate the intestinal epithelial cells, multiply, and spread to adjacent cells, causing tissue destruction and inflammation. This process is facilitated by a set of virulence factors encoded on a 140-MDa [[plasmid]]. | EIEC pathogenesis involves the invasion and destruction of the [[intestinal epithelium]]. The bacteria penetrate the intestinal epithelial cells, multiply, and spread to adjacent cells, causing tissue destruction and inflammation. This process is facilitated by a set of virulence factors encoded on a 140-MDa [[plasmid]]. | ||
==Diagnosis and Treatment== | ==Diagnosis and Treatment== | ||
Diagnosis of EIEC infection is typically made by stool culture. Treatment usually involves rehydration and, in severe cases, antibiotics. However, the increasing prevalence of [[antibiotic resistance]] among EIEC strains is a growing concern. | Diagnosis of EIEC infection is typically made by stool culture. Treatment usually involves rehydration and, in severe cases, antibiotics. However, the increasing prevalence of [[antibiotic resistance]] among EIEC strains is a growing concern. | ||
==Epidemiology== | ==Epidemiology== | ||
EIEC is a significant cause of [[bacterial gastroenteritis]] worldwide, particularly in developing countries with poor sanitation. Outbreaks are often associated with contaminated food and water. | EIEC is a significant cause of [[bacterial gastroenteritis]] worldwide, particularly in developing countries with poor sanitation. Outbreaks are often associated with contaminated food and water. | ||
==Prevention== | ==Prevention== | ||
Prevention of EIEC infection primarily involves proper food handling and sanitation practices. There is currently no vaccine available for EIEC. | Prevention of EIEC infection primarily involves proper food handling and sanitation practices. There is currently no vaccine available for EIEC. | ||
==See also== | ==See also== | ||
* [[Escherichia coli]] | * [[Escherichia coli]] | ||
* [[Shigellosis]] | * [[Shigellosis]] | ||
* [[Bacterial gastroenteritis]] | * [[Bacterial gastroenteritis]] | ||
{{Bacteria-stub}} | {{Bacteria-stub}} | ||
[[Category:Bacteria]] | [[Category:Bacteria]] | ||
| Line 31: | Line 38: | ||
[[Category:Escherichia coli]] | [[Category:Escherichia coli]] | ||
{{No image}} | {{No image}} | ||
Latest revision as of 03:26, 4 April 2025
| Enteroinvasive Escherichia coli | |
|---|---|
| Synonyms | EIEC |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Diarrhea, fever, abdominal pain, dysentery |
| Complications | Dehydration, hemolytic uremic syndrome |
| Onset | 1-3 days after exposure |
| Duration | 5-7 days |
| Types | N/A |
| Causes | Escherichia coli (EIEC) |
| Risks | Contaminated food, contaminated water, poor sanitation |
| Diagnosis | Stool culture, polymerase chain reaction (PCR) |
| Differential diagnosis | Shigellosis, Salmonellosis, Campylobacteriosis |
| Prevention | Hand washing, safe food handling, clean water supply |
| Treatment | Rehydration therapy, antibiotics in severe cases |
| Medication | Ciprofloxacin, Azithromycin |
| Prognosis | Generally good with treatment |
| Frequency | Rare in developed countries |
| Deaths | N/A |
Enteroinvasive Escherichia coli (EIEC) is a type of pathogenic bacteria that is closely related to Shigella species in genetic and pathogenic terms. EIEC is one of the six recognized categories of diarrheagenic Escherichia coli.
Characteristics[edit]
EIEC strains are characterized by their ability to invade epithelial cells of the colon, causing a disease similar to Shigellosis. The primary symptoms of EIEC infection include diarrhea, abdominal cramps, and fever.
Pathogenesis[edit]
EIEC pathogenesis involves the invasion and destruction of the intestinal epithelium. The bacteria penetrate the intestinal epithelial cells, multiply, and spread to adjacent cells, causing tissue destruction and inflammation. This process is facilitated by a set of virulence factors encoded on a 140-MDa plasmid.
Diagnosis and Treatment[edit]
Diagnosis of EIEC infection is typically made by stool culture. Treatment usually involves rehydration and, in severe cases, antibiotics. However, the increasing prevalence of antibiotic resistance among EIEC strains is a growing concern.
Epidemiology[edit]
EIEC is a significant cause of bacterial gastroenteritis worldwide, particularly in developing countries with poor sanitation. Outbreaks are often associated with contaminated food and water.
Prevention[edit]
Prevention of EIEC infection primarily involves proper food handling and sanitation practices. There is currently no vaccine available for EIEC.
