CDV3 (gene): Difference between revisions

Latest revision as of 14:12, 21 February 2025

CDV3 (gene)[edit]

Chromosomal location of the CDV3 gene.

CDV3 (Caspase recruitment domain family member 3) is a gene that encodes a protein involved in various cellular processes, including apoptosis and immune response. The CDV3 gene is located on chromosome 3 in humans.

Structure[edit]

The CDV3 gene consists of multiple exons and introns, which are transcribed and spliced to produce a mature mRNA. The protein encoded by CDV3 is predicted to have a specific secondary structure, as shown in the accompanying image. This structure is crucial for its function in cellular processes.

The three-dimensional structure of the CDV3 protein has been predicted using computational models. This structure provides insights into the potential functional domains and interaction sites of the protein.

Expression[edit]

The expression of CDV3 varies across different tissues. RNA sequencing data indicates that CDV3 is expressed in several human tissues, with varying levels of expression. This differential expression suggests that CDV3 may have tissue-specific roles.

In addition to linear mRNA, CDV3 is also involved in the formation of circular RNAs, which are known to play roles in gene regulation and cellular stress responses.

Function[edit]

CDV3 is involved in the regulation of apoptosis and immune responses. It interacts with other proteins in the cell to modulate these processes. The protein's structure and expression patterns suggest it may have additional roles in cellular signaling pathways.

Regulation[edit]

The activity of the CDV3 protein is regulated by various post-translational modifications. These modifications can alter the protein's function and interactions, thereby influencing cellular processes.

Transcriptome[edit]

Transcriptome analysis has revealed the presence of CDV3 transcripts in multiple human tissues. This data provides a comprehensive view of the gene's expression profile and potential functional roles.

The Illumina BodyMap2 project has further characterized the expression of CDV3, highlighting its presence in various tissues and its potential involvement in diverse biological processes.

Related pages[edit]

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-{{Short description|Human gene encoding CDV3 protein}}
+== CDV3 (gene) ==
-{{DISPLAYTITLE:CDV3 (gene)}}
-==CDV3 (gene)==
+[[File:CDV3_Chromosome_Location.jpg|thumb|right|Chromosomal location of the CDV3 gene.]]
-The '''CDV3''' gene, also known as '''Caspase recruitment domain family member 3''', is a gene in humans that encodes a protein involved in various cellular processes. This gene is located on chromosome 3 and is expressed in multiple tissues throughout the body.
-==Function==
+'''CDV3''' (Caspase recruitment domain family member 3) is a gene that encodes a protein involved in various cellular processes, including apoptosis and immune response. The CDV3 gene is located on chromosome 3 in humans.
-The protein encoded by the CDV3 gene is involved in [[cell signaling]] pathways that regulate [[apoptosis]], or programmed cell death. It plays a crucial role in maintaining cellular homeostasis and preventing the proliferation of damaged cells. The CDV3 protein is part of the [[caspase]] recruitment domain (CARD) family, which is known for its role in mediating interactions between proteins involved in apoptotic and inflammatory processes.
-==Structure==
+== Structure ==
-The CDV3 protein contains a CARD domain, which is a protein interaction module that facilitates the assembly of signaling complexes. This domain is essential for the protein's function in apoptosis and inflammation. The structure of the CDV3 protein allows it to interact with other CARD-containing proteins, thereby influencing various signaling pathways.
-==Expression==
+[[File:Predicted_secondary_structure_of_CDV3.png|thumb|left|Predicted secondary structure of the CDV3 protein.]]
-CDV3 is ubiquitously expressed in human tissues, with higher expression levels observed in the [[immune system]], particularly in [[lymphocytes]] and [[macrophages]]. This widespread expression pattern suggests that CDV3 plays a fundamental role in immune regulation and cellular stress responses.
-==Clinical Significance==
+The CDV3 gene consists of multiple exons and introns, which are transcribed and spliced to produce a mature mRNA. The protein encoded by CDV3 is predicted to have a specific secondary structure, as shown in the accompanying image. This structure is crucial for its function in cellular processes.
-Mutations or dysregulation of the CDV3 gene can lead to impaired apoptotic processes, which may contribute to the development of certain diseases, including [[cancer]] and [[autoimmune disorders]]. Understanding the function and regulation of CDV3 is important for developing therapeutic strategies targeting these conditions.
-==Research==
+[[File:Predicted_CDV3_3D_Structure.png|thumb|right|Predicted 3D structure of the CDV3 protein.]]
-Ongoing research is focused on elucidating the precise mechanisms by which CDV3 influences apoptosis and inflammation. Studies are also exploring the potential of CDV3 as a biomarker for disease diagnosis and prognosis, as well as a target for novel therapeutic interventions.
-==Images==
+The three-dimensional structure of the CDV3 protein has been predicted using computational models. This structure provides insights into the potential functional domains and interaction sites of the protein.
-[[File:Protein structure.svg|thumb|right|200px|Diagram of a protein structure, illustrating the CARD domain typical of CDV3.]]
-[[File:Apoptosis.svg|thumb|left|200px|Illustration of the apoptosis pathway, highlighting the role of CARD-containing proteins like CDV3.]]
+== Expression ==
-==Related pages==
+[[File:CDV3_Human_HPA_RNA-seq_Normal_Tissue_Expression.png|thumb|left|RNA-seq data showing CDV3 expression in normal human tissues.]]
+The expression of CDV3 varies across different tissues. RNA sequencing data indicates that CDV3 is expressed in several human tissues, with varying levels of expression. This differential expression suggests that CDV3 may have tissue-specific roles.
+[[File:Tissue-specific_circular_RNA_induction_for_CDV3.png|thumb|right|Tissue-specific circular RNA induction for CDV3.]]
+In addition to linear mRNA, CDV3 is also involved in the formation of circular RNAs, which are known to play roles in gene regulation and cellular stress responses.
+== Function ==
+CDV3 is involved in the regulation of apoptosis and immune responses. It interacts with other proteins in the cell to modulate these processes. The protein's structure and expression patterns suggest it may have additional roles in cellular signaling pathways.
+== Regulation ==
+[[File:Predicted_Sites_of_CDV3_Protein_Regulation.png|thumb|left|Predicted sites of regulation on the CDV3 protein.]]
+The activity of the CDV3 protein is regulated by various post-translational modifications. These modifications can alter the protein's function and interactions, thereby influencing cellular processes.
+== Transcriptome ==
+[[File:CDV3_RNA_sequencing_of_total_RNA_from_20_human_tissues.png|thumb|right|RNA sequencing of total RNA from 20 human tissues showing CDV3 expression.]]
+Transcriptome analysis has revealed the presence of CDV3 transcripts in multiple human tissues. This data provides a comprehensive view of the gene's expression profile and potential functional roles.
+[[File:CDV3_Illumina_bodyMap2_transcriptome.png|thumb|left|Illumina BodyMap2 transcriptome data for CDV3.]]
+The Illumina BodyMap2 project has further characterized the expression of CDV3, highlighting its presence in various tissues and its potential involvement in diverse biological processes.
+== Related pages ==
 * [[Apoptosis]]
-* [[Caspase]]
+* [[Immune response]]
-* [[Immune system]]
 * [[Chromosome 3 (human)]]
+* [[Gene expression]]
 [[Category:Human genes]]
 [[Category:Apoptosis]]
 [[Category:Immune system]]