OR13C5

OR13C5 is a gene that in humans is encoded by the OR13C5 olfactory receptor family 13 subfamily C member 5. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome.

Function

The OR13C5 gene is part of the olfactory receptor family, which is involved in the detection of smell. Olfactory receptors are proteins that bind odor molecules and trigger a neural response that leads to the perception of a smell. The olfactory receptor family is the largest gene family in the human genome, and includes around 800 genes in humans.

Structure

The OR13C5 gene is located on chromosome 1, specifically on the long (q) arm at position 44. The gene spans approximately 1,000 base pairs. The encoded protein is 312 amino acids in length.

Clinical significance

While the specific clinical significance of OR13C5 is not yet fully understood, olfactory receptors in general have been linked to various diseases. For example, mutations in certain olfactory receptors have been associated with a decreased sense of smell, known as anosmia.

See also

• Olfactory receptor
• G protein-coupled receptor
• Anosmia

References

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External links

• OR13C5 at NCBI
• OR13C5 at GeneCards

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