Gougerot–Blum syndrome: Difference between revisions
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[[File:Jcm-10-02283-g004-550.jpg| | {{SI}} | ||
{{Infobox medical condition | |||
| name = Gougerot–Blum syndrome | |||
| image = [[File:Jcm-10-02283-g004-550.jpg]] | |||
| caption = Clinical presentation of Gougerot–Blum syndrome | |||
| synonyms = Pigmented purpuric lichenoid dermatitis | |||
| specialty = [[Dermatology]] | |||
| symptoms = [[Purpura]], [[lichenification]], [[pigmentation]] | |||
| onset = Typically in [[adulthood]] | |||
| duration = Chronic | |||
| causes = Unknown | |||
| risks = Possible [[genetic predisposition]] | |||
| diagnosis = [[Clinical diagnosis]], [[skin biopsy]] | |||
| differential = [[Schamberg's disease]], [[lichen planus]] | |||
| treatment = [[Topical corticosteroids]], [[phototherapy]] | |||
| prognosis = Generally good with treatment | |||
| frequency = Rare | |||
}} | |||
'''Gougerot–Blum syndrome''' is a rare [[dermatological]] condition characterized by the presence of [[lichenoid]] and [[pigmented purpuric dermatosis]]. It is named after the French dermatologists [[Henri Gougerot]] and [[Paul Blum]], who first described the syndrome. | |||
== Clinical Features == | == Clinical Features == | ||
Gougerot–Blum syndrome typically presents with small, reddish-brown [[papules]] that may coalesce into larger plaques. These lesions are often found on the lower extremities but can also appear on the trunk and upper limbs. The condition is chronic and may persist for many years. | Gougerot–Blum syndrome typically presents with small, reddish-brown [[papules]] that may coalesce into larger plaques. These lesions are often found on the lower extremities but can also appear on the trunk and upper limbs. The condition is chronic and may persist for many years. | ||
== Pathophysiology == | == Pathophysiology == | ||
The exact cause of Gougerot–Blum syndrome is unknown. It is believed to be an [[autoimmune]] disorder, where the body's immune system mistakenly attacks its own skin cells. Histopathological examination usually reveals a lichenoid tissue reaction with a band-like infiltrate of [[lymphocytes]] at the dermoepidermal junction. | The exact cause of Gougerot–Blum syndrome is unknown. It is believed to be an [[autoimmune]] disorder, where the body's immune system mistakenly attacks its own skin cells. Histopathological examination usually reveals a lichenoid tissue reaction with a band-like infiltrate of [[lymphocytes]] at the dermoepidermal junction. | ||
== Diagnosis == | == Diagnosis == | ||
Diagnosis is primarily clinical, supported by [[skin biopsy]] findings. The biopsy typically shows features of both lichenoid dermatitis and pigmented purpuric dermatosis. Differential diagnosis includes other lichenoid disorders such as [[lichen planus]] and other pigmented purpuric dermatoses like [[Schamberg's disease]]. | Diagnosis is primarily clinical, supported by [[skin biopsy]] findings. The biopsy typically shows features of both lichenoid dermatitis and pigmented purpuric dermatosis. Differential diagnosis includes other lichenoid disorders such as [[lichen planus]] and other pigmented purpuric dermatoses like [[Schamberg's disease]]. | ||
== Treatment == | == Treatment == | ||
There is no definitive cure for Gougerot–Blum syndrome. Treatment is symptomatic and may include topical [[corticosteroids]], [[calcineurin inhibitors]], and [[phototherapy]]. In some cases, systemic treatments such as [[immunosuppressive drugs]] may be considered. | There is no definitive cure for Gougerot–Blum syndrome. Treatment is symptomatic and may include topical [[corticosteroids]], [[calcineurin inhibitors]], and [[phototherapy]]. In some cases, systemic treatments such as [[immunosuppressive drugs]] may be considered. | ||
== Prognosis == | == Prognosis == | ||
The prognosis for Gougerot–Blum syndrome is generally good, although the condition can be persistent and may require long-term management. It is not associated with any significant morbidity or mortality. | The prognosis for Gougerot–Blum syndrome is generally good, although the condition can be persistent and may require long-term management. It is not associated with any significant morbidity or mortality. | ||
== See Also == | == See Also == | ||
* [[Lichen planus]] | * [[Lichen planus]] | ||
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* [[Autoimmune skin disorders]] | * [[Autoimmune skin disorders]] | ||
* [[Dermatology]] | * [[Dermatology]] | ||
== References == | == References == | ||
{{Reflist}} | {{Reflist}} | ||
== External Links == | == External Links == | ||
{{Commons category|Gougerot–Blum syndrome}} | {{Commons category|Gougerot–Blum syndrome}} | ||
[[Category:Dermatology]] | [[Category:Dermatology]] | ||
[[Category:Autoimmune diseases]] | [[Category:Autoimmune diseases]] | ||
[[Category:Rare diseases]] | [[Category:Rare diseases]] | ||
[[Category:Skin conditions resulting from errors in metabolism]] | [[Category:Skin conditions resulting from errors in metabolism]] | ||
{{medicine-stub}} | {{medicine-stub}} | ||
Latest revision as of 01:47, 7 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Gougerot–Blum syndrome | |
|---|---|
| |
| Synonyms | Pigmented purpuric lichenoid dermatitis |
| Pronounce | N/A |
| Specialty | Dermatology |
| Symptoms | Purpura, lichenification, pigmentation |
| Complications | N/A |
| Onset | Typically in adulthood |
| Duration | Chronic |
| Types | N/A |
| Causes | Unknown |
| Risks | Possible genetic predisposition |
| Diagnosis | Clinical diagnosis, skin biopsy |
| Differential diagnosis | Schamberg's disease, lichen planus |
| Prevention | N/A |
| Treatment | Topical corticosteroids, phototherapy |
| Medication | N/A |
| Prognosis | Generally good with treatment |
| Frequency | Rare |
| Deaths | N/A |
Gougerot–Blum syndrome is a rare dermatological condition characterized by the presence of lichenoid and pigmented purpuric dermatosis. It is named after the French dermatologists Henri Gougerot and Paul Blum, who first described the syndrome.
Clinical Features[edit]
Gougerot–Blum syndrome typically presents with small, reddish-brown papules that may coalesce into larger plaques. These lesions are often found on the lower extremities but can also appear on the trunk and upper limbs. The condition is chronic and may persist for many years.
Pathophysiology[edit]
The exact cause of Gougerot–Blum syndrome is unknown. It is believed to be an autoimmune disorder, where the body's immune system mistakenly attacks its own skin cells. Histopathological examination usually reveals a lichenoid tissue reaction with a band-like infiltrate of lymphocytes at the dermoepidermal junction.
Diagnosis[edit]
Diagnosis is primarily clinical, supported by skin biopsy findings. The biopsy typically shows features of both lichenoid dermatitis and pigmented purpuric dermatosis. Differential diagnosis includes other lichenoid disorders such as lichen planus and other pigmented purpuric dermatoses like Schamberg's disease.
Treatment[edit]
There is no definitive cure for Gougerot–Blum syndrome. Treatment is symptomatic and may include topical corticosteroids, calcineurin inhibitors, and phototherapy. In some cases, systemic treatments such as immunosuppressive drugs may be considered.
Prognosis[edit]
The prognosis for Gougerot–Blum syndrome is generally good, although the condition can be persistent and may require long-term management. It is not associated with any significant morbidity or mortality.
See Also[edit]
References[edit]
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External Links[edit]
