Methylisopropyllysergamide: Difference between revisions

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'''Methylisopropyllysergamide''' (also known as '''MIPLA''') is a [[psychedelic drug]] that belongs to the [[lysergamide]] family. It was first synthesized by the renowned chemist [[Albert Hofmann]], who also discovered [[lysergic acid diethylamide|LSD]].
== Methylisopropyllysergamide ==


==Chemistry==
[[File:MIPLSD.svg|thumb|right|Chemical structure of Methylisopropyllysergamide]]
Methylisopropyllysergamide is a derivative of [[lysergic acid]], which is a complex molecule that serves as the base structure for a variety of psychedelic substances. The chemical structure of MIPLA is similar to that of LSD, with the key difference being the substitution of the diethylamide group in LSD with a methylisopropylamide group in MIPLA.


==Pharmacology==
'''Methylisopropyllysergamide''' (MIPLA) is a chemical compound that belongs to the class of [[lysergamides]], which are derivatives of [[lysergic acid]]. MIPLA is structurally related to [[lysergic acid diethylamide]] (LSD), a well-known psychedelic substance. The compound is of interest in the field of [[psychopharmacology]] due to its potential effects on the [[central nervous system]].
The exact mechanism of action of MIPLA is not fully understood. However, it is believed to act primarily as a [[serotonin receptor]] agonist, similar to other psychedelic drugs. This means that it binds to and activates certain serotonin receptors in the brain, which leads to its psychedelic effects.


==Effects==
== Chemical Structure and Properties ==
The effects of MIPLA are reported to be less intense than those of LSD, but still distinctly psychedelic. Users often report visual distortions, enhanced sensory perception, and altered thought patterns. However, the subjective effects of MIPLA can vary greatly depending on the individual and the context in which the drug is used.


==Safety==
Methylisopropyllysergamide is characterized by the presence of a lysergic acid core with an isopropyl group and a methyl group attached to the amide nitrogen. This modification distinguishes it from other lysergamides such as LSD, which has two ethyl groups attached to the amide nitrogen.
As with all psychedelic substances, the use of MIPLA carries potential risks. These can include psychological distress, dangerous behavior due to impaired judgment, and potential legal consequences. It is important to use MIPLA responsibly and in a safe, supportive environment.


==Legal Status==
The chemical formula of MIPLA is C20H26N2O, and it has a molecular weight of 310.44 g/mol. The compound is typically synthesized in a laboratory setting and is not found naturally.
The legal status of MIPLA varies by country. In some jurisdictions, it is classified as a controlled substance, while in others it is legal to possess and use.


==See Also==
== Pharmacology ==
* [[Lysergic acid diethylamide|LSD]]
 
MIPLA is believed to act as a partial agonist at the [[serotonin receptor|5-HT2A receptor]], similar to other lysergamides. This receptor is known to play a significant role in the modulation of mood, perception, and cognition, which are often affected by psychedelic substances.
 
The pharmacokinetics of MIPLA, including its absorption, distribution, metabolism, and excretion, are not well-documented in the scientific literature. However, it is assumed to share some similarities with other lysergamides in terms of its metabolic pathways.
 
== Potential Effects ==
 
While specific studies on MIPLA are limited, it is hypothesized to produce effects similar to those of LSD, including altered sensory perception, changes in mood, and cognitive shifts. The intensity and duration of these effects can vary based on dosage, individual physiology, and environmental factors.
 
== Legal Status ==
 
The legal status of MIPLA varies by country. In some jurisdictions, it may be classified as a controlled substance due to its structural similarity to LSD and potential for psychoactive effects. Researchers interested in studying MIPLA must often obtain special licenses or permissions to work with the compound.
 
== Related Compounds ==
 
MIPLA is part of a broader class of compounds known as lysergamides, which include:
 
* [[Lysergic acid diethylamide]] (LSD)
* [[Ergometrine]]
* [[Ergotamine]]
 
These compounds share a common lysergic acid backbone but differ in their side chain modifications, which can significantly influence their pharmacological profiles.
 
== Related Pages ==
 
* [[Lysergic acid diethylamide]]
* [[Psychedelic drug]]
* [[Psychedelic drug]]
* [[Serotonin receptor]]
* [[Serotonin receptor]]


[[Category:Lysergamides]]
[[Category:Psychedelic drugs]]
[[Category:Psychedelic drugs]]
[[Category:Lysergamides]]
[[Category:Chemical compounds]]
[[Category:Pharmacology]]
{{Psychoactive substance}}
{{medicine-stub}}

Latest revision as of 12:06, 15 February 2025

Methylisopropyllysergamide[edit]

Chemical structure of Methylisopropyllysergamide

Methylisopropyllysergamide (MIPLA) is a chemical compound that belongs to the class of lysergamides, which are derivatives of lysergic acid. MIPLA is structurally related to lysergic acid diethylamide (LSD), a well-known psychedelic substance. The compound is of interest in the field of psychopharmacology due to its potential effects on the central nervous system.

Chemical Structure and Properties[edit]

Methylisopropyllysergamide is characterized by the presence of a lysergic acid core with an isopropyl group and a methyl group attached to the amide nitrogen. This modification distinguishes it from other lysergamides such as LSD, which has two ethyl groups attached to the amide nitrogen.

The chemical formula of MIPLA is C20H26N2O, and it has a molecular weight of 310.44 g/mol. The compound is typically synthesized in a laboratory setting and is not found naturally.

Pharmacology[edit]

MIPLA is believed to act as a partial agonist at the 5-HT2A receptor, similar to other lysergamides. This receptor is known to play a significant role in the modulation of mood, perception, and cognition, which are often affected by psychedelic substances.

The pharmacokinetics of MIPLA, including its absorption, distribution, metabolism, and excretion, are not well-documented in the scientific literature. However, it is assumed to share some similarities with other lysergamides in terms of its metabolic pathways.

Potential Effects[edit]

While specific studies on MIPLA are limited, it is hypothesized to produce effects similar to those of LSD, including altered sensory perception, changes in mood, and cognitive shifts. The intensity and duration of these effects can vary based on dosage, individual physiology, and environmental factors.

Legal Status[edit]

The legal status of MIPLA varies by country. In some jurisdictions, it may be classified as a controlled substance due to its structural similarity to LSD and potential for psychoactive effects. Researchers interested in studying MIPLA must often obtain special licenses or permissions to work with the compound.

Related Compounds[edit]

MIPLA is part of a broader class of compounds known as lysergamides, which include:

These compounds share a common lysergic acid backbone but differ in their side chain modifications, which can significantly influence their pharmacological profiles.

Related Pages[edit]