Anisocoria: Difference between revisions

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'''Anisocoria''' is a medical condition characterized by unequal pupil sizes. It is a common condition, occurring in approximately 20% of the population. Anisocoria can be a normal variant, or it can be a sign of a medical condition that requires treatment.
== Anisocoria ==


==Causes==
[[File:Anisocoria0.jpg|thumb|right|An example of anisocoria, where the pupils are of unequal sizes.]]
Anisocoria can be caused by a variety of conditions. These include:


* [[Horner's syndrome]]
'''Anisocoria''' is a condition characterized by an unequal size of the [[pupil]]s. It is a common condition, occurring in approximately 20% of the population. Anisocoria can be a benign finding or a sign of more serious medical conditions.
* [[Adie's pupil]]
 
* [[Third nerve palsy]]
== Causes ==
* [[Pharmacological agents]]
Anisocoria can result from a variety of causes, which can be broadly categorized into physiological and pathological causes.
* [[Trauma]]
* [[Infection]]
* [[Migraine]]


==Diagnosis==
=== Physiological Anisocoria ===
The diagnosis of anisocoria is made by a healthcare provider who will take a detailed medical history and perform a physical examination. The examination will include a detailed examination of the eyes, including the use of a [[slit lamp]] to examine the front part of the eye.
Physiological anisocoria is a benign condition where the difference in pupil size is usually less than 1 mm and does not change with different lighting conditions. It is often idiopathic and does not require treatment.


==Treatment==
=== Pathological Anisocoria ===
The treatment of anisocoria depends on the underlying cause. If the anisocoria is caused by a medical condition, such as Horner's syndrome or third nerve palsy, treatment will be directed at the underlying condition. If the anisocoria is caused by a pharmacological agent, the agent may need to be discontinued.
Pathological anisocoria can be due to:


==Prognosis==
* '''[[Horner's syndrome]]''': A condition caused by disruption of the sympathetic nerves supplying the eye, leading to ptosis, miosis, and anhidrosis.
The prognosis for anisocoria depends on the underlying cause. In many cases, anisocoria is a benign condition that does not require treatment. However, in some cases, anisocoria can be a sign of a serious medical condition that requires treatment.
* '''[[Adie's tonic pupil]]''': A neurological disorder where one pupil is larger than normal and reacts slowly to light.
* '''[[Third nerve palsy]]''': A condition affecting the third cranial nerve, leading to ptosis, "down and out" eye position, and pupil dilation.
* '''[[Iritis]] or [[uveitis]]''': Inflammation of the iris or uveal tract can cause anisocoria due to irregular pupil shape or size.
* '''[[Pharmacological agents]]''': Certain medications or drugs can cause anisocoria by affecting the muscles of the iris.


[[Category:Ophthalmology]]
== Diagnosis ==
[[Category:Neurology]]
The diagnosis of anisocoria involves a thorough [[medical history]] and [[physical examination]]. Key steps include:
[[Category:Symptoms and signs]]


{{medicine-stub}}
* '''Observation in different lighting conditions''': To determine if the anisocoria is more pronounced in bright or dim light.
* '''Slit-lamp examination''': To assess the anterior segment of the eye for any abnormalities.
* '''Neurological examination''': To check for any associated neurological signs that might indicate a more serious underlying condition.


==References==
== Treatment ==
<references />
Treatment of anisocoria depends on the underlying cause. Physiological anisocoria does not require treatment. Pathological anisocoria requires addressing the underlying condition, which may involve:


==External links==
* '''Medications''': For conditions like uveitis or iritis.
* [http://www.nlm.nih.gov/medlineplus/ency/article/003314.htm MedlinePlus Encyclopedia 003314]
* '''Surgery''': In cases of structural abnormalities or tumors.
* [http://www.fpnotebook.com/Eye/Exam/Ansocr.htm Family Practice Notebook - Anisocoria]
* '''Observation''': In cases where the cause is benign and self-limiting.


==See also==
== Related pages ==
* [[Adie syndrome]]
* [[Pupil]]
* [[Holmes-Adie syndrome]]
* [[Horner's syndrome]]
* [[Horner's syndrome]]
* [[Adie's tonic pupil]]
* [[Third nerve palsy]]
* [[Third nerve palsy]]
* [[Tonic pupil]]
* [[Iritis]]
* [[Uveitis]]


==Further reading==
[[Category:Ophthalmology]]
* [http://www.ncbi.nlm.nih.gov/pubmed/16722796 PubMed - Anisocoria: Case Presentations and Review of the Literature]
[[Category:Neurology]]
* [http://www.ncbi.nlm.nih.gov/pubmed/16722796 PubMed - Anisocoria: Current Concepts and Recent Advances]
 
==External links==
* [http://www.nlm.nih.gov/medlineplus/ency/article/003314.htm MedlinePlus Encyclopedia 003314]
* [http://www.fpnotebook.com/Eye/Exam/Ansocr.htm Family Practice Notebook - Anisocoria]
 
{{DEFAULTSORT:Anisocoria}}

Revision as of 04:00, 13 February 2025

Anisocoria

An example of anisocoria, where the pupils are of unequal sizes.

Anisocoria is a condition characterized by an unequal size of the pupils. It is a common condition, occurring in approximately 20% of the population. Anisocoria can be a benign finding or a sign of more serious medical conditions.

Causes

Anisocoria can result from a variety of causes, which can be broadly categorized into physiological and pathological causes.

Physiological Anisocoria

Physiological anisocoria is a benign condition where the difference in pupil size is usually less than 1 mm and does not change with different lighting conditions. It is often idiopathic and does not require treatment.

Pathological Anisocoria

Pathological anisocoria can be due to:

  • Horner's syndrome: A condition caused by disruption of the sympathetic nerves supplying the eye, leading to ptosis, miosis, and anhidrosis.
  • Adie's tonic pupil: A neurological disorder where one pupil is larger than normal and reacts slowly to light.
  • Third nerve palsy: A condition affecting the third cranial nerve, leading to ptosis, "down and out" eye position, and pupil dilation.
  • Iritis or uveitis: Inflammation of the iris or uveal tract can cause anisocoria due to irregular pupil shape or size.
  • Pharmacological agents: Certain medications or drugs can cause anisocoria by affecting the muscles of the iris.

Diagnosis

The diagnosis of anisocoria involves a thorough medical history and physical examination. Key steps include:

  • Observation in different lighting conditions: To determine if the anisocoria is more pronounced in bright or dim light.
  • Slit-lamp examination: To assess the anterior segment of the eye for any abnormalities.
  • Neurological examination: To check for any associated neurological signs that might indicate a more serious underlying condition.

Treatment

Treatment of anisocoria depends on the underlying cause. Physiological anisocoria does not require treatment. Pathological anisocoria requires addressing the underlying condition, which may involve:

  • Medications: For conditions like uveitis or iritis.
  • Surgery: In cases of structural abnormalities or tumors.
  • Observation: In cases where the cause is benign and self-limiting.

Related pages