OR2B11: Difference between revisions

OR2B11
Symbol	OR2B11
HGNC ID	14857
Alternative symbols	–
Entrez Gene	–
OMIM	–
RefSeq	–
UniProt	–
Chromosome	6q23
Locus supplementary data	–

Latest revision as of 20:37, 30 December 2024

OR2B11 is a gene that encodes a member of the olfactory receptor family of proteins. These proteins are involved in the detection of odor molecules and are part of the G-protein-coupled receptor (GPCR) superfamily. Olfactory receptors are responsible for the sense of smell (olfaction) and are located in the olfactory epithelium of the nasal cavity.

Function[edit]

Olfactory receptors, such as OR2B11, interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals.

Gene family[edit]

The olfactory receptor gene family is the largest in the human genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

Location[edit]

The OR2B11 gene is located on the long arm (q) of chromosome 6 at position 23.

References[edit]

External links[edit]

@@ Line 1: / Line 1: @@
-'''OR2B11''' is a gene that encodes a protein in the olfactory receptor family. The [[olfactory receptor]] family is the largest in the genome. The family members are G-protein coupled receptors that respond to odor molecules and are responsible for our sense of smell. The OR2B11 gene is specifically expressed in the olfactory epithelium.
+{{Infobox gene
+| name = OR2B11
+| symbol = OR2B11
+| HGNCid = 14857
+| chromosome = 6
+| arm = q
+| band = 23
+}}
-== Function ==
+'''OR2B11''' is a gene that encodes a member of the olfactory receptor family of proteins. These proteins are involved in the detection of odor molecules and are part of the G-protein-coupled receptor (GPCR) superfamily. Olfactory receptors are responsible for the sense of smell ([[olfaction]]) and are located in the [[olfactory epithelium]] of the nasal cavity.
-The OR2B11 gene encodes a member of the olfactory receptor family of proteins. These proteins are a part of the [[G protein-coupled receptor]] superfamily. The receptors in this family are responsible for detecting odor molecules in the nose and initiating a neuronal response that triggers the perception of a smell. The olfactory receptor gene family is the largest in the genome, and the specific function of this receptor has not been determined.
-== Expression ==
+==Function==
-The OR2B11 gene is predominantly expressed in the [[olfactory epithelium]], a specialized epithelial tissue inside the nasal cavity that is involved in smell. In humans, the olfactory epithelium is about 2.5 square centimeters, and is located in the upper part of the nasal cavity.
+Olfactory receptors, such as OR2B11, interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals.
-== Clinical Significance ==
+==Gene family==
-While the specific function of the OR2B11 gene is not yet fully understood, mutations in this gene and others in the olfactory receptor family have been associated with a decreased sense of smell, known as [[anosmia]]. Further research is needed to understand the potential clinical significance of this gene.
+The olfactory receptor gene family is the largest in the human genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.
-[[File:Olfactory system diagram en.svg|thumb|right|Diagram of the olfactory system, showing the olfactory epithelium (green).]]
+==Location==
+The OR2B11 gene is located on the long arm (q) of [[chromosome 6]] at position 23.
-== See Also ==
+==See also==
 * [[Olfactory receptor]]
-* [[G protein-coupled receptor]]
+* [[G-protein-coupled receptor]]
-* [[Anosmia]]
+* [[Olfaction]]
-== References ==
+==References==
-<references />
+{{Reflist}}
-[[Category:Genes]]
+==External links==
-[[Category:Olfactory system]]
+* [https://www.ncbi.nlm.nih.gov/gene/OR2B11 OR2B11 Gene - NCBI]
+* [https://www.genecards.org/cgi-bin/carddisp.pl?gene=OR2B11 OR2B11 Gene - GeneCards]
+[[Category:Olfactory receptors]]
+[[Category:Genes on human chromosome 6]]
 [[Category:G protein-coupled receptors]]
-{{medicine-stub}}