Decidual cells: Difference between revisions

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'''Decidual cells''' are specialized cells that originate within the [[endometrium]] (the inner lining of the [[uterus]]) during the [[menstrual cycle]]. These cells play a crucial role in the process of [[implantation]] and the establishment of [[pregnancy]].


== Function ==
{{Short description|Cells that form the maternal part of the placenta}}
{{Infobox cell
| name = Decidual cell
| image =  
| image_size =  
| image_alt =  
| caption =
| Latin =
| precurso = [[Endometrial stromal cell]]
| function = Support [[embryo]] implantation and [[placenta]] formation
| location = [[Uterus]]
}}


Decidual cells are primarily responsible for the changes that occur in the endometrium during the menstrual cycle and pregnancy. They secrete proteins and other factors that are essential for the successful implantation of the [[embryo]] and the maintenance of pregnancy. These cells also play a role in the immune response, helping to prevent the mother's immune system from rejecting the embryo.
'''Decidual cells''' are specialized cells that form in the [[endometrium]] of the [[uterus]] during [[pregnancy]]. These cells play a crucial role in the establishment and maintenance of the [[maternal-fetal interface]].


== Formation ==
==Formation==
Decidual cells originate from [[endometrial stromal cells]] in response to the hormonal changes that occur during the [[menstrual cycle]] and early pregnancy. The process of transformation from stromal cells to decidual cells is known as [[decidualization]]. This transformation is primarily driven by the hormone [[progesterone]].


Decidual cells are formed from the stromal cells of the endometrium in a process known as decidualization. This process is triggered by the hormone [[progesterone]], which is produced by the [[corpus luteum]] after [[ovulation]]. Decidualization involves the transformation of stromal cells into large, polygonal decidual cells. This transformation is characterized by an increase in cell size, the accumulation of glycogen and lipids, and the production of various proteins and growth factors.
==Function==
Decidual cells are essential for successful [[embryo]] implantation and the formation of the [[placenta]]. They provide structural and nutritional support to the developing [[embryo]] and help modulate the maternal [[immune system]] to prevent rejection of the [[fetus]].


== Role in Pregnancy ==
==Role in Pregnancy==
During pregnancy, decidual cells contribute to the formation of the [[decidua]], which is the modified mucosal lining of the [[uterus]]. The decidua is divided into three regions:
* '''Decidua basalis''': The part of the decidua that interacts with the [[trophoblast]] cells of the [[placenta]].
* '''Decidua capsularis''': The part of the decidua that surrounds the [[embryo]].
* '''Decidua parietalis''': The remaining part of the decidua lining the [[uterus]].


During pregnancy, decidual cells play a crucial role in supporting the developing embryo. They provide nutrients to the embryo, secrete hormones that regulate the pregnancy, and produce factors that protect the embryo from the mother's immune system. Decidual cells also contribute to the formation of the [[placenta]], the organ that provides oxygen and nutrients to the developing fetus.
==Clinical Significance==
Abnormalities in decidual cell function can lead to complications in pregnancy, such as [[preeclampsia]], [[miscarriage]], and [[preterm birth]]. Research into decidual cell biology is ongoing to better understand their role in these conditions and to develop potential therapeutic interventions.


== Pathology ==
==See also==
 
Abnormalities in the function or formation of decidual cells can lead to various reproductive disorders, including [[infertility]], [[miscarriage]], and [[preeclampsia]]. Research is ongoing to better understand the role of these cells in these conditions and to develop potential treatments.
 
[[File:Decidual cells.jpg|thumb|Decidual cells under a microscope]]
 
== See also ==
* [[Endometrium]]
* [[Endometrium]]
* [[Menstrual cycle]]
* [[Placenta]]
* [[Embryo]]
* [[Pregnancy]]
* [[Pregnancy]]
* [[Progesterone]]
* [[Corpus luteum]]


== References ==
==References==
<references />
{{Reflist}}
 
==External links==
* [https://www.wikimd.com/wiki/Decidual_cells Decidual cells on WikiMD]


[[Category:Cell biology]]
[[Category:Cell biology]]
[[Category:Reproductive system]]
[[Category:Reproductive system]]
[[Category:Human female endocrine system]]
[[Category:Pregnancy]]
[[Category:Human pregnancy]]
{{anatomy-stub}}

Latest revision as of 21:29, 27 December 2024


Cells that form the maternal part of the placenta



Decidual cell





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Decidual cells are specialized cells that form in the endometrium of the uterus during pregnancy. These cells play a crucial role in the establishment and maintenance of the maternal-fetal interface.

Formation[edit]

Decidual cells originate from endometrial stromal cells in response to the hormonal changes that occur during the menstrual cycle and early pregnancy. The process of transformation from stromal cells to decidual cells is known as decidualization. This transformation is primarily driven by the hormone progesterone.

Function[edit]

Decidual cells are essential for successful embryo implantation and the formation of the placenta. They provide structural and nutritional support to the developing embryo and help modulate the maternal immune system to prevent rejection of the fetus.

Role in Pregnancy[edit]

During pregnancy, decidual cells contribute to the formation of the decidua, which is the modified mucosal lining of the uterus. The decidua is divided into three regions:

  • Decidua basalis: The part of the decidua that interacts with the trophoblast cells of the placenta.
  • Decidua capsularis: The part of the decidua that surrounds the embryo.
  • Decidua parietalis: The remaining part of the decidua lining the uterus.

Clinical Significance[edit]

Abnormalities in decidual cell function can lead to complications in pregnancy, such as preeclampsia, miscarriage, and preterm birth. Research into decidual cell biology is ongoing to better understand their role in these conditions and to develop potential therapeutic interventions.

See also[edit]

References[edit]

<references group="" responsive="1"></references>


External links[edit]

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