Triplatin tetranitrate: Difference between revisions

Revision as of 16:11, 9 February 2025

A chemical compound of platinum and nitrate

Triplatinum tetranitrate is a chemical compound with the formula Pt_(NO_)_. It is a coordination compound consisting of three platinum atoms and four nitrate groups. This compound is of interest in the field of inorganic chemistry due to its unique structure and potential applications.

Structure

Triplatinum tetranitrate is characterized by its complex structure, where three platinum atoms are linked together, and each platinum atom is coordinated to nitrate groups. The exact arrangement of these atoms and groups can vary, but it typically involves bridging nitrate ligands that connect the platinum centers. The compound is often studied using techniques such as X-ray crystallography to determine its precise molecular geometry.

Synthesis

The synthesis of triplatinum tetranitrate involves the reaction of platinum metal or platinum compounds with nitric acid under controlled conditions. The process requires careful handling due to the reactivity of nitric acid and the potential for the formation of various platinum-nitrate complexes. The resulting product is purified through crystallization or other separation techniques to obtain the desired compound.

Properties

Triplatinum tetranitrate is known for its distinctive chemical properties, which are influenced by the presence of multiple platinum centers and nitrate groups. It is typically a solid at room temperature and may exhibit various colors depending on its specific form and purity. The compound is soluble in certain solvents, which allows for its use in various chemical reactions and applications.

Applications

While triplatinum tetranitrate is primarily of interest for research purposes, it has potential applications in catalysis and materials science. The unique properties of platinum compounds make them valuable in catalytic processes, and the study of triplatinum tetranitrate can contribute to the development of new catalysts. Additionally, its structural characteristics may be explored for use in the design of novel materials.

Safety and Handling

As with many chemical compounds, triplatinum tetranitrate should be handled with care. It is important to use appropriate safety equipment and procedures when working with this compound to prevent exposure and potential hazards. The compound should be stored in a cool, dry place, away from incompatible substances.

Related pages

References

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-'''Triplatin Tetranitrate''' is a [[non-classical platinum compound]] that has been studied for its potential use in [[cancer treatment]]. Unlike classical platinum compounds such as [[cisplatin]], [[carboplatin]], and [[oxaliplatin]], triplatin tetranitrate does not bind to DNA in the traditional sense. Instead, it interacts with the [[phosphate backbone]] of DNA, a property that gives it unique [[anti-cancer]] activity.
+{{Short description|A chemical compound of platinum and nitrate}}
+{{Use dmy dates|date=October 2023}}
+[[File:Triplatinum_tetranitrate_final.png|thumb|right|Structure of triplatinum tetranitrate]]
+'''Triplatinum tetranitrate''' is a chemical compound with the formula Pt_(NO_)_. It is a coordination compound consisting of three platinum atoms and four nitrate groups. This compound is of interest in the field of inorganic chemistry due to its unique structure and potential applications.
-==Chemistry==
+==Structure==
-Triplatin tetranitrate is a [[bimetallic]] compound, meaning it contains two [[platinum]] atoms. The platinum atoms are connected by a [[diamine]] bridge, and each platinum atom is also bound to two [[nitrate]] ions. The compound is positively charged, which allows it to interact with the negatively charged phosphate backbone of DNA.
+Triplatinum tetranitrate is characterized by its complex structure, where three platinum atoms are linked together, and each platinum atom is coordinated to nitrate groups. The exact arrangement of these atoms and groups can vary, but it typically involves bridging nitrate ligands that connect the platinum centers. The compound is often studied using techniques such as X-ray crystallography to determine its precise molecular geometry.
-==Mechanism of Action==
+==Synthesis==
-The mechanism of action of triplatin tetranitrate is unique among platinum compounds. Instead of forming [[covalent bond]]s with DNA, it forms [[ionic bond]]s with the phosphate backbone. This interaction distorts the DNA structure and interferes with the ability of the cell to read the DNA code, leading to cell death.
+The synthesis of triplatinum tetranitrate involves the reaction of platinum metal or platinum compounds with nitric acid under controlled conditions. The process requires careful handling due to the reactivity of nitric acid and the potential for the formation of various platinum-nitrate complexes. The resulting product is purified through crystallization or other separation techniques to obtain the desired compound.
-==Clinical Use==
+==Properties==
-Triplatin tetranitrate is currently in the experimental stage and has not yet been approved for clinical use. However, early studies have shown promising results. In particular, triplatin tetranitrate has been found to be effective against [[cancer cells]] that are resistant to classical platinum compounds.
+Triplatinum tetranitrate is known for its distinctive chemical properties, which are influenced by the presence of multiple platinum centers and nitrate groups. It is typically a solid at room temperature and may exhibit various colors depending on its specific form and purity. The compound is soluble in certain solvents, which allows for its use in various chemical reactions and applications.
-==Safety and Side Effects==
+==Applications==
-As with all [[chemotherapy]] drugs, triplatin tetranitrate has potential side effects. These can include [[nausea]], [[vomiting]], and [[hair loss]]. However, because it does not bind to DNA in the same way as classical platinum compounds, it may have a different side effect profile. More research is needed to fully understand the safety and side effects of this compound.
+While triplatinum tetranitrate is primarily of interest for research purposes, it has potential applications in catalysis and materials science. The unique properties of platinum compounds make them valuable in catalytic processes, and the study of triplatinum tetranitrate can contribute to the development of new catalysts. Additionally, its structural characteristics may be explored for use in the design of novel materials.
-==See Also==
+==Safety and Handling==
-* [[Platinum-based antineoplastic]]
+As with many chemical compounds, triplatinum tetranitrate should be handled with care. It is important to use appropriate safety equipment and procedures when working with this compound to prevent exposure and potential hazards. The compound should be stored in a cool, dry place, away from incompatible substances.
-* [[DNA-binding ligand]]
-* [[Chemotherapy]]
+==Related pages==
+* [[Platinum]]
+* [[Nitrate]]
+* [[Coordination complex]]
+==References==
+{{Reflist}}
-{{Chemistry-stub}}
-[[Category:Chemotherapy agents]]
 [[Category:Platinum compounds]]
-[[Category:Experimental cancer drugs]]
+[[Category:Nitrates]]
+[[Category:Coordination complexes]]