Nitroxyl

Nitroxyl (also known as HNO) is a reactive nitrogen species that is a powerful reducing agent. It is the one-electron reduction product of nitric oxide (NO) and is isoelectronic with dioxygen. Nitroxyl can be formed from the reduction of nitric oxide or from the protonation of nitroxide (NO−). Nitroxyl is a powerful reducing agent, and it reacts with oxygen to form nitric oxide and water.

Chemistry

Nitroxyl is a reactive nitrogen species that is a powerful reducing agent. It is the one-electron reduction product of nitric oxide (NO) and is isoelectronic with dioxygen. Nitroxyl can be formed from the reduction of nitric oxide or from the protonation of nitroxide (NO−). Nitroxyl is a powerful reducing agent, and it reacts with oxygen to form nitric oxide and water.

Biological role

In biological systems, nitroxyl has been found to have a number of important roles. It is involved in the regulation of vascular tone, neurotransmission, and immune response. Nitroxyl can also react with a number of biological targets, including thiols, metals, and nucleophiles.

Medical applications

Due to its biological activity, nitroxyl has potential applications in medicine. It has been shown to have vasodilatory effects, and it may have potential as a treatment for heart failure. Nitroxyl donors have also been investigated for their potential as anticancer agents.

See also

• Nitric oxide
• Reactive nitrogen species
• Nitroxide

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