TAN-67: Difference between revisions

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'''TAN-67''' is a drug that acts as a potent and selective [[agonist]] for the [[delta opioid receptor]].<ref>{{cite journal | vauthors = Fujii H, Nagase H, Morimoto Y, Matsui H, Yamamoto I, Yoshimura H | title = TAN-67, a delta opioid receptor agonist, reduces ischemia-induced neuronal damage in rat hippocampus | journal = Brain Research | volume = 745 | issue = 1–2 | pages = 96–104 | date = January 1997 | pmid = 9037402 | doi = 10.1016/S0006-8993(96)01132-6 }}</ref> It has [[analgesic]] effects and is used in scientific research. TAN-67 has been found to protect against [[ischemia]]-induced neuronal damage in the [[hippocampus]] of rats.<ref>{{cite journal | vauthors = Fujii H, Nagase H, Morimoto Y, Matsui H, Yamamoto I, Yoshimura H | title = TAN-67, a delta opioid receptor agonist, reduces ischemia-induced neuronal damage in rat hippocampus | journal = Brain Research | volume = 745 | issue = 1–2 | pages = 96–104 | date = January 1997 | pmid = 9037402 | doi = 10.1016/S0006-8993(96)01132-6 }}</ref>
{{DISPLAYTITLE:TAN-67}}


==Pharmacology==
== Overview ==
TAN-67 is a selective [[delta opioid receptor]] agonist, meaning it binds to and activates these receptors in the body. This activation is responsible for the drug's analgesic effects.<ref>{{cite journal | vauthors = Fujii H, Nagase H, Morimoto Y, Matsui H, Yamamoto I, Yoshimura H | title = TAN-67, a delta opioid receptor agonist, reduces ischemia-induced neuronal damage in rat hippocampus | journal = Brain Research | volume = 745 | issue = 1–2 | pages = 96–104 | date = January 1997 | pmid = 9037402 | doi = 10.1016/S0006-8993(96)01132-6 }}</ref>
[[File:TAN-67.svg|thumb|right|Chemical structure of TAN-67]]
'''TAN-67''' is a chemical compound known for its role as a selective [[delta-opioid receptor]] agonist. It is primarily used in scientific research to study the effects of delta-opioid receptor activation in various physiological and pathological processes.


==Medical Uses==
== Chemical Properties ==
While TAN-67 is primarily used in scientific research, its analgesic properties suggest potential therapeutic applications. Its ability to reduce ischemia-induced neuronal damage could make it a valuable tool in the treatment of conditions such as [[stroke]] and other forms of [[brain injury]].<ref>{{cite journal | vauthors = Fujii H, Nagase H, Morimoto Y, Matsui H, Yamamoto I, Yoshimura H | title = TAN-67, a delta opioid receptor agonist, reduces ischemia-induced neuronal damage in rat hippocampus | journal = Brain Research | volume = 745 | issue = 1–2 | pages = 96–104 | date = January 1997 | pmid = 9037402 | doi = 10.1016/S0006-8993(96)01132-6 }}</ref>
TAN-67 is a synthetic compound with a specific chemical structure that allows it to selectively bind to delta-opioid receptors. The chemical structure of TAN-67 is depicted in the image to the right. This structure is crucial for its activity and selectivity as a delta-opioid receptor agonist.


==See Also==
== Mechanism of Action ==
TAN-67 exerts its effects by binding to and activating the [[delta-opioid receptor]], a type of [[opioid receptor]] that is part of the [[G protein-coupled receptor]] family. Activation of these receptors can lead to various physiological effects, including modulation of pain perception, mood, and immune responses.
 
== Pharmacological Effects ==
The activation of delta-opioid receptors by TAN-67 has been shown to produce analgesic effects, making it a compound of interest in pain management research. Additionally, delta-opioid receptor agonists like TAN-67 are being studied for their potential roles in neuroprotection and the treatment of mood disorders.
 
== Research Applications ==
[[File:TAN-67.svg|thumb|left|Another view of TAN-67's chemical structure]]
TAN-67 is widely used in preclinical studies to explore the therapeutic potential of delta-opioid receptor agonists. Research involving TAN-67 includes investigations into its effects on [[pain management]], [[neuroprotection]], and [[immune system]] modulation.
 
== Safety and Toxicology ==
As with many research chemicals, the safety profile of TAN-67 is primarily characterized in controlled laboratory settings. It is important to handle TAN-67 with care, following appropriate safety protocols to avoid any potential adverse effects.
 
== Related Pages ==
* [[Delta-opioid receptor]]
* [[Opioid receptor]]
* [[Opioid receptor]]
* [[Agonist]]
* [[G protein-coupled receptor]]
* [[Analgesic]]
* [[Analgesic]]
* [[Ischemia]]
* [[Hippocampus]]
==References==
<references />


[[Category:Drugs]]
[[Category:Opioids]]
[[Category:Opioids]]
[[Category:Agonists]]
[[Category:Research chemicals]]
{{stub}}

Latest revision as of 03:37, 13 February 2025


Overview[edit]

File:TAN-67.svg
Chemical structure of TAN-67

TAN-67 is a chemical compound known for its role as a selective delta-opioid receptor agonist. It is primarily used in scientific research to study the effects of delta-opioid receptor activation in various physiological and pathological processes.

Chemical Properties[edit]

TAN-67 is a synthetic compound with a specific chemical structure that allows it to selectively bind to delta-opioid receptors. The chemical structure of TAN-67 is depicted in the image to the right. This structure is crucial for its activity and selectivity as a delta-opioid receptor agonist.

Mechanism of Action[edit]

TAN-67 exerts its effects by binding to and activating the delta-opioid receptor, a type of opioid receptor that is part of the G protein-coupled receptor family. Activation of these receptors can lead to various physiological effects, including modulation of pain perception, mood, and immune responses.

Pharmacological Effects[edit]

The activation of delta-opioid receptors by TAN-67 has been shown to produce analgesic effects, making it a compound of interest in pain management research. Additionally, delta-opioid receptor agonists like TAN-67 are being studied for their potential roles in neuroprotection and the treatment of mood disorders.

Research Applications[edit]

File:TAN-67.svg
Another view of TAN-67's chemical structure

TAN-67 is widely used in preclinical studies to explore the therapeutic potential of delta-opioid receptor agonists. Research involving TAN-67 includes investigations into its effects on pain management, neuroprotection, and immune system modulation.

Safety and Toxicology[edit]

As with many research chemicals, the safety profile of TAN-67 is primarily characterized in controlled laboratory settings. It is important to handle TAN-67 with care, following appropriate safety protocols to avoid any potential adverse effects.

Related Pages[edit]