JWH-047: Difference between revisions
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== JWH-047 == | |||
[[File:JWH-047.svg|thumb|right|Chemical structure of JWH-047]] | |||
JWH-047 is a | '''JWH-047''' is a synthetic [[cannabinoid]] that acts as a potent agonist at the [[cannabinoid receptor]]s. It is part of the [[naphthoylindole]] family of compounds, which are known for their ability to mimic the effects of [[tetrahydrocannabinol]] (THC), the primary psychoactive component of [[cannabis]]. | ||
== | === Chemical Properties === | ||
JWH-047 is characterized by its unique chemical structure, which includes a naphthoyl group attached to an indole core. This structure is crucial for its activity at the cannabinoid receptors, particularly the [[CB1 receptor|CB1]] and [[CB2 receptor|CB2]] receptors. The presence of the naphthoyl group is a common feature among synthetic cannabinoids, contributing to their high affinity and selectivity for these receptors. | |||
JWH-047 | === Pharmacology === | ||
JWH-047 functions primarily as a full agonist at the CB1 and CB2 receptors. These receptors are part of the [[endocannabinoid system]], which plays a significant role in regulating various physiological processes, including [[pain]], [[appetite]], and [[mood]]. The activation of these receptors by JWH-047 can lead to effects similar to those produced by natural cannabinoids, such as [[analgesia]], [[euphoria]], and [[sedation]]. | |||
== | === Synthesis === | ||
The synthesis of JWH-047 involves the condensation of a naphthoyl chloride with an indole derivative. This process is typical for the production of naphthoylindole cannabinoids and requires careful control of reaction conditions to ensure the desired product is obtained with high purity and yield. | |||
=== Legal Status === | |||
Due to its potential for abuse and lack of medical use, JWH-047, like many synthetic cannabinoids, is classified as a controlled substance in many jurisdictions. The legal status of these compounds can vary significantly between countries, with some having specific legislation targeting synthetic cannabinoids as a class. | |||
== | === Potential Risks and Effects === | ||
[[File:JWH-047.svg|thumb|left|Another view of the chemical structure of JWH-047]] | |||
The use of JWH-047, particularly in unregulated settings, poses several health risks. These include [[tachycardia]], [[hypertension]], [[anxiety]], and [[psychosis]]. The variability in potency and purity of synthetic cannabinoids like JWH-047 can lead to unpredictable effects, making their use particularly dangerous. | |||
* [[Synthetic | == Related Pages == | ||
* [[ | * [[Cannabinoid receptor]] | ||
* [[ | * [[Synthetic cannabinoid]] | ||
* [[Endocannabinoid system]] | |||
* [[Naphthoylindole]] | |||
[[Category:Synthetic cannabinoids]] | [[Category:Synthetic cannabinoids]] | ||
Latest revision as of 03:43, 13 February 2025
JWH-047[edit]
JWH-047 is a synthetic cannabinoid that acts as a potent agonist at the cannabinoid receptors. It is part of the naphthoylindole family of compounds, which are known for their ability to mimic the effects of tetrahydrocannabinol (THC), the primary psychoactive component of cannabis.
Chemical Properties[edit]
JWH-047 is characterized by its unique chemical structure, which includes a naphthoyl group attached to an indole core. This structure is crucial for its activity at the cannabinoid receptors, particularly the CB1 and CB2 receptors. The presence of the naphthoyl group is a common feature among synthetic cannabinoids, contributing to their high affinity and selectivity for these receptors.
Pharmacology[edit]
JWH-047 functions primarily as a full agonist at the CB1 and CB2 receptors. These receptors are part of the endocannabinoid system, which plays a significant role in regulating various physiological processes, including pain, appetite, and mood. The activation of these receptors by JWH-047 can lead to effects similar to those produced by natural cannabinoids, such as analgesia, euphoria, and sedation.
Synthesis[edit]
The synthesis of JWH-047 involves the condensation of a naphthoyl chloride with an indole derivative. This process is typical for the production of naphthoylindole cannabinoids and requires careful control of reaction conditions to ensure the desired product is obtained with high purity and yield.
Legal Status[edit]
Due to its potential for abuse and lack of medical use, JWH-047, like many synthetic cannabinoids, is classified as a controlled substance in many jurisdictions. The legal status of these compounds can vary significantly between countries, with some having specific legislation targeting synthetic cannabinoids as a class.
Potential Risks and Effects[edit]
The use of JWH-047, particularly in unregulated settings, poses several health risks. These include tachycardia, hypertension, anxiety, and psychosis. The variability in potency and purity of synthetic cannabinoids like JWH-047 can lead to unpredictable effects, making their use particularly dangerous.
