Enterodiol: Difference between revisions
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{{DISPLAYTITLE:Enterodiol}} | |||
== | == Overview == | ||
[[File:Enterodiol.png|thumb|right|Chemical structure of Enterodiol]] | |||
'''Enterodiol''' is a type of [[lignan]], which is a class of [[phytoestrogens]] found in plants. It is a metabolite of [[secoisolariciresinol diglucoside]] (SDG), a lignan found in high concentrations in [[flaxseed]] and other seeds. Enterodiol is produced in the human body by the action of intestinal bacteria on plant lignans. | |||
Enterodiol is a | == Chemical Structure == | ||
Enterodiol is characterized by its two phenolic rings and a diol group, which contribute to its biological activity. The chemical structure of enterodiol allows it to mimic [[estrogen]] by binding to estrogen receptors, although it is much weaker than endogenous estrogens. | |||
== | == Biological Role == | ||
Enterodiol, along with its related compound [[enterolactone]], is considered to have potential health benefits due to its [[antioxidant]] properties and its ability to modulate estrogenic activity. These compounds are thought to play a role in reducing the risk of [[hormone-dependent cancers]], such as [[breast cancer]] and [[prostate cancer]]. | |||
Enterodiol is | == Metabolism == | ||
Enterodiol is formed in the [[gastrointestinal tract]] from plant lignans by the action of [[gut microbiota]]. The conversion of plant lignans to enterodiol involves several steps, including the hydrolysis of SDG to secoisolariciresinol, which is then converted to enterodiol by bacterial enzymes. | |||
== Health | == Health Implications == | ||
The consumption of lignan-rich foods, such as flaxseed, is associated with various health benefits, including improved [[cardiovascular health]], reduced risk of certain cancers, and improved [[menopausal symptoms]]. Enterodiol, as a phytoestrogen, may contribute to these effects by modulating estrogenic activity in the body. | |||
== Related Compounds == | |||
* [[Enterolactone]] | |||
* [[Secoisolariciresinol diglucoside]] | |||
* [[Phytoestrogens]] | |||
== Related Pages == | |||
* [[Lignan]] | * [[Lignan]] | ||
* [[Phytoestrogen]] | * [[Phytoestrogen]] | ||
* [[ | * [[Flaxseed]] | ||
* [[ | * [[Gut microbiota]] | ||
[[Category:Phytoestrogens]] | [[Category:Phytoestrogens]] | ||
[[Category:Lignans]] | [[Category:Lignans]] | ||
Latest revision as of 03:52, 13 February 2025
Overview[edit]
Enterodiol is a type of lignan, which is a class of phytoestrogens found in plants. It is a metabolite of secoisolariciresinol diglucoside (SDG), a lignan found in high concentrations in flaxseed and other seeds. Enterodiol is produced in the human body by the action of intestinal bacteria on plant lignans.
Chemical Structure[edit]
Enterodiol is characterized by its two phenolic rings and a diol group, which contribute to its biological activity. The chemical structure of enterodiol allows it to mimic estrogen by binding to estrogen receptors, although it is much weaker than endogenous estrogens.
Biological Role[edit]
Enterodiol, along with its related compound enterolactone, is considered to have potential health benefits due to its antioxidant properties and its ability to modulate estrogenic activity. These compounds are thought to play a role in reducing the risk of hormone-dependent cancers, such as breast cancer and prostate cancer.
Metabolism[edit]
Enterodiol is formed in the gastrointestinal tract from plant lignans by the action of gut microbiota. The conversion of plant lignans to enterodiol involves several steps, including the hydrolysis of SDG to secoisolariciresinol, which is then converted to enterodiol by bacterial enzymes.
Health Implications[edit]
The consumption of lignan-rich foods, such as flaxseed, is associated with various health benefits, including improved cardiovascular health, reduced risk of certain cancers, and improved menopausal symptoms. Enterodiol, as a phytoestrogen, may contribute to these effects by modulating estrogenic activity in the body.
