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'''Stroke volume''' ('''SV''') is the volume of blood pumped from the left ventricle per beat. It is measured in milliliters (ml) and varies depending on various factors such as heart rate, contractility, and blood pressure. Stroke volume is a crucial component of [[cardiac output]], which is the total volume of blood pumped by the heart per minute.
{{Short description|An overview of stroke volume in cardiovascular physiology}}


== Calculation ==
==Stroke Volume==
Stroke volume is calculated using the formula: SV = EDV - ESV. Where:
[[File:2035_Factors_in_Stroke_Volume.jpg|thumb|right|Factors influencing stroke volume]]
* '''EDV''' ('''End Diastolic Volume''') is the total volume of blood in the ventricle immediately before a contraction (systole).
'''Stroke volume''' (SV) is the volume of blood pumped from the left ventricle of the heart with each beat. It is a critical component of [[cardiac output]], which is the total volume of blood the heart pumps per minute. Stroke volume is influenced by several factors, including preload, afterload, and contractility.
* '''ESV''' ('''End Systolic Volume''') is the volume of blood left in the ventricle after contraction.


== Factors affecting stroke volume ==
==Determinants of Stroke Volume==
Several factors can affect stroke volume, including:
Stroke volume is determined by three primary factors:
* '''Preload''': The initial stretching of the cardiac myocytes prior to contraction. It is related to [[ventricular filling]].
* '''Afterload''': The pressure that the heart must work against to eject blood during systole.
* '''Contractility''': The inherent vigor of contraction of the heart muscles, independent of preload.


== Clinical significance ==
===Preload===
Stroke volume is an important indicator of cardiac health. Abnormal stroke volume can be a sign of several heart conditions, including [[heart failure]], [[cardiomyopathy]], and [[valvular heart disease]]. It is also a critical parameter in the management of [[shock]] and [[sepsis]].
Preload refers to the initial stretching of the cardiac myocytes prior to contraction. It is related to the ventricular filling and is influenced by the venous return to the heart. The greater the preload, the greater the stroke volume, according to the [[Frank-Starling law of the heart]].


== See also ==
===Afterload===
* [[Cardiac output]]
Afterload is the pressure against which the heart must work to eject blood during systole. It is primarily determined by the [[systemic vascular resistance]] and the condition of the aortic valve. An increase in afterload can decrease stroke volume.
* [[Ejection fraction]]
* [[Heart rate]]
* [[Frank-Starling law]]


[[Category:Cardiology]]
===Contractility===
[[Category:Cardiovascular physiology]]
Contractility refers to the intrinsic ability of cardiac muscle fibers to contract at a given fiber length. It is influenced by factors such as [[sympathetic nervous system]] activity and circulating catecholamines. Increased contractility enhances stroke volume.


{{stub}}
==Clinical Significance==
Stroke volume is an important parameter in assessing cardiac function. It can be affected in various pathological conditions such as [[heart failure]], [[myocardial infarction]], and [[valvular heart disease]]. Understanding stroke volume and its determinants is crucial for diagnosing and managing these conditions.


== References ==
==Measurement==
<references />
Stroke volume can be measured using several techniques, including echocardiography, cardiac catheterization, and magnetic resonance imaging (MRI). These methods provide insights into the heart's pumping efficiency and help guide treatment decisions.


== External links ==
==Related pages==
* [https://www.ncbi.nlm.nih.gov/pubmedhealth/PMHT0022278/ Stroke Volume] at [[PubMed Health]]
* [[Cardiac output]]
* [http://www.cvphysiology.com/Cardiac%20Function/CF002.htm Stroke Volume] at Cardiovascular Physiology Concepts
* [[Frank-Starling law of the heart]]
* [[Heart failure]]
* [[Myocardial infarction]]
* [[Valvular heart disease]]


{{Cardiovascular system physiology}}
[[Category:Cardiovascular physiology]]
{{Cardiology}}

Latest revision as of 05:34, 16 February 2025

An overview of stroke volume in cardiovascular physiology


Stroke Volume[edit]

Factors influencing stroke volume

Stroke volume (SV) is the volume of blood pumped from the left ventricle of the heart with each beat. It is a critical component of cardiac output, which is the total volume of blood the heart pumps per minute. Stroke volume is influenced by several factors, including preload, afterload, and contractility.

Determinants of Stroke Volume[edit]

Stroke volume is determined by three primary factors:

Preload[edit]

Preload refers to the initial stretching of the cardiac myocytes prior to contraction. It is related to the ventricular filling and is influenced by the venous return to the heart. The greater the preload, the greater the stroke volume, according to the Frank-Starling law of the heart.

Afterload[edit]

Afterload is the pressure against which the heart must work to eject blood during systole. It is primarily determined by the systemic vascular resistance and the condition of the aortic valve. An increase in afterload can decrease stroke volume.

Contractility[edit]

Contractility refers to the intrinsic ability of cardiac muscle fibers to contract at a given fiber length. It is influenced by factors such as sympathetic nervous system activity and circulating catecholamines. Increased contractility enhances stroke volume.

Clinical Significance[edit]

Stroke volume is an important parameter in assessing cardiac function. It can be affected in various pathological conditions such as heart failure, myocardial infarction, and valvular heart disease. Understanding stroke volume and its determinants is crucial for diagnosing and managing these conditions.

Measurement[edit]

Stroke volume can be measured using several techniques, including echocardiography, cardiac catheterization, and magnetic resonance imaging (MRI). These methods provide insights into the heart's pumping efficiency and help guide treatment decisions.

Related pages[edit]