Macroovalocyte

Macroovalocyte is a type of red blood cell that is larger and more oval in shape than a typical red blood cell. Macroovalocytes are often associated with certain types of anemia, particularly megaloblastic anemia and pernicious anemia.

Overview

Macroovalocytes are a type of poikilocyte, which is a term used to describe red blood cells that have an abnormal shape. The presence of macroovalocytes can be a sign of an underlying health condition, such as vitamin B12 or folate deficiency, which can lead to the development of megaloblastic anemia.

Causes

The most common cause of macroovalocytosis is vitamin B12 or folate deficiency. These vitamins are essential for the production of red blood cells, and a deficiency can lead to the production of larger, oval-shaped cells. Other causes can include alcoholism, liver disease, and certain medications.

Diagnosis

Macroovalocytosis is typically diagnosed through a complete blood count (CBC) test, which measures the size and shape of red blood cells. If macroovalocytes are present, further tests may be needed to determine the underlying cause.

Treatment

Treatment for macroovalocytosis typically involves addressing the underlying cause. This may involve supplementation with vitamin B12 or folate, or changes to medication or alcohol consumption.

See also

• Anemia
• Megaloblastic anemia
• Pernicious anemia
• Vitamin B12
• Folate
• Complete blood count

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