Lecirelin

Lecirelin is a synthetic form of gonadotropin-releasing hormone (GnRH) used in veterinary medicine. It is primarily used in the treatment of cystic ovarian disease in cattle.

Etymology

The term "Lecirelin" is derived from the chemical structure of the compound. The prefix "Leci-" is derived from the Latin word "lecin", meaning "to stimulate", and the suffix "-relin" is a common suffix used in the names of GnRH analogues.

Pharmacology

Lecirelin acts by stimulating the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the anterior pituitary gland. These hormones then act on the ovaries to stimulate ovulation and the production of progesterone, a hormone necessary for the maintenance of pregnancy.

Uses

In veterinary medicine, lecirelin is used to treat cystic ovarian disease in cattle. This condition is characterized by the presence of large, fluid-filled cysts in the ovaries that prevent normal ovulation. By stimulating the release of LH and FSH, lecirelin promotes the rupture of these cysts and the resumption of normal ovarian function.

Side Effects

As with all medications, lecirelin can cause side effects. The most common side effect is a temporary increase in sexual behavior in treated animals. Other potential side effects include allergic reactions and injection site reactions.

Related Terms

• Gonadotropin-releasing hormone
• Luteinizing hormone
• Follicle-stimulating hormone
• Progesterone
• Cystic ovarian disease

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