Concomitant

Concomitant refers to a medical condition or circumstance that occurs with another. In clinical research, concomitant diseases are additional conditions from which an individual suffers besides the primary disease under investigation. Concomitant medications are drugs that the individual takes in addition to the medication under investigation.

Definition

The term "concomitant" is derived from the Latin concomitari (to accompany). In medicine, it is used to describe either diseases or treatments that exist together with the primary disease or treatment.

Concomitant Diseases

Concomitant diseases are additional conditions that an individual has while being treated for a primary disease. For example, a person with cancer may also have diabetes. The presence of concomitant diseases can complicate the treatment of the primary disease due to potential drug interactions or the additional burden on the patient's health.

Concomitant Medications

Concomitant medications are additional drugs that a patient is taking while participating in a clinical trial. These medications may be used to manage concomitant diseases or to manage side effects of the primary treatment. The use of concomitant medications can complicate the interpretation of clinical trial results, as they may interact with the drug under investigation and affect its efficacy or safety.

Considerations in Clinical Trials

In clinical trials, the presence of concomitant diseases and use of concomitant medications are important considerations. They can affect patient eligibility for participation in the trial, as well as the interpretation of trial results. Researchers must carefully document and monitor concomitant diseases and medications to ensure the safety of trial participants and the validity of the trial results.

See Also

• Clinical trial
• Comorbidity
• Polypharmacy

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