C cell

C Cell is a type of cell that is found in the thyroid gland. These cells are also known as parafollicular cells and are responsible for the production and secretion of the hormone calcitonin.

Function

The primary function of C cells is the production and secretion of calcitonin. This hormone plays a crucial role in the regulation of calcium and phosphate metabolism in the body. When the levels of calcium in the blood are high, calcitonin is released to inhibit the activity of osteoclasts, the cells that break down bone to release calcium into the bloodstream. This helps to lower the levels of calcium in the blood.

Location

C cells are located in the thyroid gland, specifically in the spaces between the follicles of the thyroid. They are most commonly found in the middle and upper thirds of the thyroid lobes.

Clinical significance

Abnormalities in C cells can lead to a number of medical conditions. For example, medullary thyroid cancer is a type of cancer that originates from the C cells of the thyroid. In addition, certain genetic conditions, such as multiple endocrine neoplasia type 2 (MEN2), can cause the C cells to become hyperplastic or tumorous.

See also

• Thyroid
• Calcitonin
• Medullary thyroid cancer
• Multiple endocrine neoplasia type 2

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