Neurilemma: Difference between revisions
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Neurilemma | |||
The ''' | The '''neurilemma''', also known as the '''sheath of Schwann''', is the outermost layer of the [[myelin sheath]] surrounding the [[axon]] of a [[neuron]]. It is essential for the proper functioning of the [[peripheral nervous system]] (PNS). | ||
==Structure== | ==Structure== | ||
[[File:Gray631.png|thumb|right|Diagram of a neuron showing the neurilemma.]] | |||
The neurilemma is | The neurilemma is formed by [[Schwann cells]], which are a type of [[glial cell]] in the PNS. These cells wrap around the axon, creating a protective and insulating layer. The neurilemma is the outermost layer of this wrapping and contains the nucleus and cytoplasm of the Schwann cell. | ||
==Function== | ==Function== | ||
The primary function of the neurilemma is to protect the axon and aid in the regeneration of damaged nerve fibers. Unlike the [[central nervous system]] (CNS), where [[oligodendrocytes]] form the myelin sheath, the PNS has the ability to regenerate damaged axons, largely due to the presence of the neurilemma. | |||
==Role in Nerve Regeneration== | |||
When a nerve fiber is damaged, the neurilemma plays a crucial role in the repair process. It forms a regeneration tube that guides the growth of the new axon, allowing it to reconnect with its target cells. This regenerative capability is a key difference between the PNS and the CNS, where such regeneration is limited. | |||
==Clinical | ==Clinical Significance== | ||
Damage to the neurilemma can result in impaired nerve function and delayed healing of nerve injuries. Conditions such as [[Guillain-Barré syndrome]] and [[Charcot-Marie-Tooth disease]] can affect the neurilemma, leading to neurological symptoms. | |||
==Related pages== | |||
* [[Myelin]] | |||
* [[Schwann cell]] | |||
* [[Peripheral nervous system]] | |||
* [[ | * [[Axon]] | ||
* [[Nerve regeneration]] | * [[Nerve regeneration]] | ||
[[Category:Neuroanatomy]] | |||
Latest revision as of 14:08, 21 February 2025
Neurilemma
The neurilemma, also known as the sheath of Schwann, is the outermost layer of the myelin sheath surrounding the axon of a neuron. It is essential for the proper functioning of the peripheral nervous system (PNS).
Structure[edit]
The neurilemma is formed by Schwann cells, which are a type of glial cell in the PNS. These cells wrap around the axon, creating a protective and insulating layer. The neurilemma is the outermost layer of this wrapping and contains the nucleus and cytoplasm of the Schwann cell.
Function[edit]
The primary function of the neurilemma is to protect the axon and aid in the regeneration of damaged nerve fibers. Unlike the central nervous system (CNS), where oligodendrocytes form the myelin sheath, the PNS has the ability to regenerate damaged axons, largely due to the presence of the neurilemma.
Role in Nerve Regeneration[edit]
When a nerve fiber is damaged, the neurilemma plays a crucial role in the repair process. It forms a regeneration tube that guides the growth of the new axon, allowing it to reconnect with its target cells. This regenerative capability is a key difference between the PNS and the CNS, where such regeneration is limited.
Clinical Significance[edit]
Damage to the neurilemma can result in impaired nerve function and delayed healing of nerve injuries. Conditions such as Guillain-Barré syndrome and Charcot-Marie-Tooth disease can affect the neurilemma, leading to neurological symptoms.
