Acetergamine: Difference between revisions

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{{Short description|A chemical compound used in research}}
{{DISPLAYTITLE:Acetergamine}}
{{Drugbox
| verifiedfields = changed
| verifiedrevid = 477318123
| IUPAC_name = (2S)-2-(1H-indol-3-yl)-N,N-dimethylethanamine
| image = Acetergamine.svg
| width = 200px
| CAS_number = 61-54-1
| PubChem = 6099
| ChemSpiderID = 5874
| UNII = 8NA5SWF92O
| ChEMBL = 1201247
| C=12
| H=16
| N=2
| smiles = CN(C)CCc1c[nH]c2c1cccc2
}}


'''Acetergamine''' is a chemical compound that belongs to the class of [[tryptamines]]. It is primarily used in scientific research and has been studied for its potential effects on the [[central nervous system]].
==Overview==
'''Acetergamine''' is a synthetic compound that has been studied for its potential pharmacological effects. It is primarily of interest in the field of [[neuropharmacology]] due to its interaction with various neurotransmitter systems.


==Chemical Structure and Properties==
==Chemical Structure==
Acetergamine is a derivative of [[tryptamine]], which is a naturally occurring monoamine alkaloid. The chemical structure of acetergamine includes an indole ring, which is a common feature in many biologically active compounds. The presence of the indole ring is significant as it is involved in the compound's interaction with various [[neurotransmitter]] receptors.
[[File:Acetergamine.svg|thumb|right|Chemical structure of Acetergamine]]
Acetergamine is characterized by its unique chemical structure, which includes a complex arrangement of carbon, hydrogen, nitrogen, and oxygen atoms. This structure is crucial for its interaction with biological systems.


==Pharmacology==
==Pharmacodynamics==
Acetergamine acts as an agonist at certain [[serotonin receptor]] subtypes, particularly the 5-HT<sub>2A</sub> receptor. This interaction is thought to be responsible for its psychoactive effects. The compound's ability to modulate serotonin receptors makes it a subject of interest in the study of [[psychedelic]] substances and their potential therapeutic applications.
Acetergamine acts on the [[central nervous system]] by modulating the activity of neurotransmitters. It is known to influence the [[serotonin]] and [[dopamine]] pathways, which are critical for mood regulation and cognitive functions.


==Research Applications==
==Pharmacokinetics==
In research settings, acetergamine is used to study the effects of serotonin receptor activation. It serves as a tool for understanding the role of serotonin in mood regulation, perception, and cognition. Researchers also explore its potential use in developing treatments for [[mental health]] disorders such as [[depression]] and [[anxiety]].
The absorption, distribution, metabolism, and excretion (ADME) of Acetergamine are key factors in its pharmacokinetic profile. It is absorbed through the gastrointestinal tract and undergoes hepatic metabolism. The metabolites are primarily excreted via the renal system.


==Safety and Legal Status==
==Therapeutic Uses==
As a research chemical, acetergamine is not approved for medical use in humans. Its legal status varies by country, and it is often regulated under laws pertaining to psychoactive substances. Researchers handling acetergamine must adhere to strict safety protocols to prevent accidental exposure.
While Acetergamine is not currently approved for clinical use, it has been investigated for its potential in treating [[depression]], [[anxiety disorders]], and [[schizophrenia]]. Its ability to modulate neurotransmitter systems makes it a candidate for further research in these areas.


==Related Compounds==
==Side Effects==
Acetergamine is structurally related to other tryptamines, such as [[serotonin]], [[melatonin]], and [[psilocybin]]. These compounds share a common indole structure and have varying effects on the central nervous system.
Potential side effects of Acetergamine include [[nausea]], [[dizziness]], and [[insomnia]]. These effects are similar to those observed with other compounds that affect the central nervous system.
 
==Research and Development==
Ongoing research is focused on understanding the full spectrum of Acetergamine's effects and its potential therapeutic applications. Studies are being conducted to evaluate its efficacy and safety in various [[clinical trials]].


==Related pages==
==Related pages==
* [[Tryptamine]]
* [[Neurotransmitter]]
* [[Pharmacology]]
* [[Central nervous system]]
* [[Serotonin]]
* [[Serotonin]]
* [[Psychedelic drug]]
* [[Dopamine]]
* [[Neurotransmitter]]


[[Category:Tryptamines]]
[[Category:Pharmacology]]
[[Category:Research chemicals]]
[[Category:Neuropharmacology]]
[[Category:Serotonin receptor agonists]]

Latest revision as of 03:55, 13 February 2025


Overview[edit]

Acetergamine is a synthetic compound that has been studied for its potential pharmacological effects. It is primarily of interest in the field of neuropharmacology due to its interaction with various neurotransmitter systems.

Chemical Structure[edit]

Chemical structure of Acetergamine

Acetergamine is characterized by its unique chemical structure, which includes a complex arrangement of carbon, hydrogen, nitrogen, and oxygen atoms. This structure is crucial for its interaction with biological systems.

Pharmacodynamics[edit]

Acetergamine acts on the central nervous system by modulating the activity of neurotransmitters. It is known to influence the serotonin and dopamine pathways, which are critical for mood regulation and cognitive functions.

Pharmacokinetics[edit]

The absorption, distribution, metabolism, and excretion (ADME) of Acetergamine are key factors in its pharmacokinetic profile. It is absorbed through the gastrointestinal tract and undergoes hepatic metabolism. The metabolites are primarily excreted via the renal system.

Therapeutic Uses[edit]

While Acetergamine is not currently approved for clinical use, it has been investigated for its potential in treating depression, anxiety disorders, and schizophrenia. Its ability to modulate neurotransmitter systems makes it a candidate for further research in these areas.

Side Effects[edit]

Potential side effects of Acetergamine include nausea, dizziness, and insomnia. These effects are similar to those observed with other compounds that affect the central nervous system.

Research and Development[edit]

Ongoing research is focused on understanding the full spectrum of Acetergamine's effects and its potential therapeutic applications. Studies are being conducted to evaluate its efficacy and safety in various clinical trials.

Related pages[edit]