OR7G3

OR7G3 is a gene that encodes a protein in humans. The protein encoded by this gene is a member of the olfactory receptor family. Olfactory receptors are proteins that are responsible for detecting odor molecules in the nose. They are located on the surface of sensory neurons in the olfactory epithelium, a specialized tissue inside the nose that is involved in smell.

Function

The OR7G3 gene is part of a larger family of G protein-coupled receptors. This family is a large and diverse group of proteins that are involved in many different physiological functions. In the case of OR7G3, the protein it encodes is believed to be involved in the detection of specific odor molecules.

Structure

Like all olfactory receptors, the protein encoded by OR7G3 is a transmembrane protein. This means it spans the membrane of the sensory neurons in the olfactory epithelium. The structure of the protein allows it to bind to specific odor molecules, triggering a signal that is then sent to the brain.

Clinical significance

While the exact role of OR7G3 in human health and disease is not fully understood, olfactory receptors in general are known to play a key role in the sense of smell. Loss of function mutations in these genes can lead to anosmia, a condition characterized by a loss of the sense of smell.

See also

• Olfactory receptor
• G protein-coupled receptor
• Anosmia

References

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