Diisopropanolamine

Diisopropanolamine (often abbreviated to DIPA) is a chemical compound with the formula (CH3)2CHOHCH2NH2. It is a secondary amine and a secondary alcohol. It is used in a variety of industrial applications including as a surfactant, a corrosion inhibitor, and in the manufacture of pharmaceuticals and cosmetics.

Chemical Structure

Diisopropanolamine is a secondary amine, meaning it has two organic groups attached to the nitrogen atom. It is also a secondary alcohol, with the hydroxyl group attached to a carbon atom that is itself attached to two other carbon atoms. The molecule is chiral, meaning it has a non-superimposable mirror image.

Production

Diisopropanolamine is produced industrially by the reaction of propylene oxide with ammonia. This reaction produces a mixture of mono-, di-, and triisopropanolamines, which can be separated by distillation.

Uses

Diisopropanolamine is used in a variety of industrial applications. It is a common ingredient in cosmetics, where it is used as a pH adjuster and emulsifier. It is also used in the manufacture of pharmaceuticals, where it can act as a solubilizer for poorly soluble drugs.

In industry, diisopropanolamine is used as a corrosion inhibitor, particularly in the oil and gas industry. It is also used as a surfactant in the production of detergents and cleaning products.

Safety

Diisopropanolamine is generally considered safe for use in cosmetics and pharmaceuticals. However, it can cause skin and eye irritation, and prolonged exposure can lead to respiratory problems. It is not considered a carcinogen.

See Also

• Amine
• Alcohol (chemistry)
• Propylene oxide
• Ammonia
• Corrosion inhibitor
• Surfactant

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  Diisopropanolamine structure
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  Diisopropanolamine synthesis