OR4N5

OR4N5 is a gene that in humans encodes the olfactory receptor, family 4, subfamily N, member 5. Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes.

Function

Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

Gene

The OR4N5 gene is located on chromosome 1, specifically at 1q44. The gene spans approximately 1.1 kilobases and consists of a single coding exon. The exact function of this gene is not known, but it is believed to play a crucial role in the detection of specific odors in the nose.

Clinical significance

While the exact clinical significance of OR4N5 is not fully understood, it is believed that mutations in this gene could potentially affect the sense of smell. Further research is needed to fully understand the potential implications of this gene in human health and disease.

See also

• Olfactory receptor
• G protein-coupled receptor
• Chromosome 1 (human)

References

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