OR5T3

OR5T3 is a gene that encodes a protein in humans. This protein is a member of the olfactory receptor family, a class of G protein-coupled receptors which are involved in the detection of smell. The OR5T3 gene is located on chromosome 1, specifically at 1q44.

Function

The olfactory receptor proteins are members of a large family of G-protein coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

Clinical significance

While the specific clinical significance of OR5T3 is not yet fully understood, olfactory receptors in general have been implicated in various diseases. For example, mutations in olfactory receptors have been linked to anosmia, a condition characterized by the inability to perceive smell. Further research is needed to determine the specific role of OR5T3 in human health and disease.

See also

• Olfactory receptor
• G protein-coupled receptor
• Anosmia

References

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