Non-celiac gluten sensitivity: Difference between revisions
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{{SI}} | |||
{{Infobox medical condition | |||
| name = Non-celiac gluten sensitivity | |||
| image = [[File:Gluten_ataxia_eng.ogg|thumb|left|Gluten ataxia]] | |||
| caption = | |||
| field = [[Gastroenterology]], [[Neurology]] | |||
| symptoms = [[Abdominal pain]], [[Bloating]], [[Diarrhea]], [[Headache]], [[Fatigue]], [[Joint pain]], [[Brain fog]] | |||
| onset = Any age | |||
| duration = Variable, symptoms improve on a [[gluten-free diet]] | |||
| causes = [[Gluten]] ingestion | |||
| risks = | |||
| diagnosis = Exclusion of [[celiac disease]] and [[wheat allergy]] | |||
| differential = [[Celiac disease]], [[Wheat allergy]], [[Irritable bowel syndrome]] | |||
| treatment = [[Gluten-free diet]] | |||
| medication = | |||
| prognosis = Good with dietary management | |||
| frequency = Estimated 0.5% to 13% of the population | |||
| deaths = | |||
}} | |||
== Non-celiac Gluten Sensitivity == | == Non-celiac Gluten Sensitivity == | ||
'''Non-celiac Gluten Sensitivity''' ('''NCGS''') is a condition characterized by adverse reactions to gluten, a protein found in wheat, barley, and rye, in individuals who do not have celiac disease or wheat allergy. The symptoms of NCGS are similar to those of celiac disease, but the overall clinical picture is less severe. | '''Non-celiac Gluten Sensitivity''' ('''NCGS''') is a condition characterized by adverse reactions to gluten, a protein found in wheat, barley, and rye, in individuals who do not have celiac disease or wheat allergy. The symptoms of NCGS are similar to those of celiac disease, but the overall clinical picture is less severe. | ||
==Definition and Classification== | ==Definition and Classification== | ||
[[Non-celiac Gluten Sensitivity]] (NCGS) is a syndrome characterized by intestinal and extraintestinal symptoms related to the ingestion of gluten-containing food, in subjects that are not affected by either celiac disease or wheat allergy. This condition is currently included in the spectrum of gluten-related disorders. | [[Non-celiac Gluten Sensitivity]] (NCGS) is a syndrome characterized by intestinal and extraintestinal symptoms related to the ingestion of gluten-containing food, in subjects that are not affected by either celiac disease or wheat allergy. This condition is currently included in the spectrum of gluten-related disorders. | ||
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==Symptoms== | ==Symptoms== | ||
The symptoms of NCGS are often similar to those of celiac disease, including abdominal pain, bloating, diarrhea, constipation, "foggy mind", rash or headache. However, there are also unique symptoms that distinguish NCGS, such as behavioral changes, bone or joint pain, muscle cramps, leg numbness, weight loss and chronic fatigue. | The symptoms of NCGS are often similar to those of celiac disease, including abdominal pain, bloating, diarrhea, constipation, "foggy mind", rash or headache. However, there are also unique symptoms that distinguish NCGS, such as behavioral changes, bone or joint pain, muscle cramps, leg numbness, weight loss and chronic fatigue. | ||
==Diagnosis== | ==Diagnosis== | ||
The diagnosis of NCGS is generally made by exclusion, that is, by ruling out other possible causes of the patient's symptoms. The [[gluten challenge]] is currently the most specific diagnostic test for NCGS, but there is no consensus on the optimal duration of the challenge. | The diagnosis of NCGS is generally made by exclusion, that is, by ruling out other possible causes of the patient's symptoms. The [[gluten challenge]] is currently the most specific diagnostic test for NCGS, but there is no consensus on the optimal duration of the challenge. | ||
==Treatment== | ==Treatment== | ||
The main treatment for NCGS is a strict [[gluten-free diet]], which should be followed under the supervision of a healthcare professional. It is important to note that a gluten-free diet is not without risks, as it may lead to deficiencies in certain nutrients. | The main treatment for NCGS is a strict [[gluten-free diet]], which should be followed under the supervision of a healthcare professional. It is important to note that a gluten-free diet is not without risks, as it may lead to deficiencies in certain nutrients. | ||
==Epidemiology== | ==Epidemiology== | ||
The prevalence of NCGS is not well established, but it is believed to be significantly higher than that of celiac disease. Some studies suggest that NCGS may affect between 0.6% and 6% of the general population. | The prevalence of NCGS is not well established, but it is believed to be significantly higher than that of celiac disease. Some studies suggest that NCGS may affect between 0.6% and 6% of the general population. | ||
==See Also== | ==See Also== | ||
* [[Celiac Disease]] | * [[Celiac Disease]] | ||
* [[Gluten-free diet]] | * [[Gluten-free diet]] | ||
* [[Gluten-related disorders]] | * [[Gluten-related disorders]] | ||
==References== | ==References== | ||
<references /> | <references /> | ||
[[Category:Gastroenterology]] | [[Category:Gastroenterology]] | ||
[[Category:Gluten sensitivity]] | [[Category:Gluten sensitivity]] | ||
Latest revision as of 05:21, 6 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD's medical weight loss NYC, sleep center NYC
Philadelphia medical weight loss and Philadelphia sleep clinics
| Non-celiac gluten sensitivity | |
|---|---|
| Synonyms | N/A |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Abdominal pain, Bloating, Diarrhea, Headache, Fatigue, Joint pain, Brain fog |
| Complications | N/A |
| Onset | Any age |
| Duration | Variable, symptoms improve on a gluten-free diet |
| Types | N/A |
| Causes | Gluten ingestion |
| Risks | |
| Diagnosis | Exclusion of celiac disease and wheat allergy |
| Differential diagnosis | Celiac disease, Wheat allergy, Irritable bowel syndrome |
| Prevention | N/A |
| Treatment | Gluten-free diet |
| Medication | |
| Prognosis | Good with dietary management |
| Frequency | Estimated 0.5% to 13% of the population |
| Deaths | |
Non-celiac Gluten Sensitivity[edit]
Non-celiac Gluten Sensitivity (NCGS) is a condition characterized by adverse reactions to gluten, a protein found in wheat, barley, and rye, in individuals who do not have celiac disease or wheat allergy. The symptoms of NCGS are similar to those of celiac disease, but the overall clinical picture is less severe.
Definition and Classification[edit]
Non-celiac Gluten Sensitivity (NCGS) is a syndrome characterized by intestinal and extraintestinal symptoms related to the ingestion of gluten-containing food, in subjects that are not affected by either celiac disease or wheat allergy. This condition is currently included in the spectrum of gluten-related disorders.
Symptoms[edit]
The symptoms of NCGS are often similar to those of celiac disease, including abdominal pain, bloating, diarrhea, constipation, "foggy mind", rash or headache. However, there are also unique symptoms that distinguish NCGS, such as behavioral changes, bone or joint pain, muscle cramps, leg numbness, weight loss and chronic fatigue.
Diagnosis[edit]
The diagnosis of NCGS is generally made by exclusion, that is, by ruling out other possible causes of the patient's symptoms. The gluten challenge is currently the most specific diagnostic test for NCGS, but there is no consensus on the optimal duration of the challenge.
Treatment[edit]
The main treatment for NCGS is a strict gluten-free diet, which should be followed under the supervision of a healthcare professional. It is important to note that a gluten-free diet is not without risks, as it may lead to deficiencies in certain nutrients.
Epidemiology[edit]
The prevalence of NCGS is not well established, but it is believed to be significantly higher than that of celiac disease. Some studies suggest that NCGS may affect between 0.6% and 6% of the general population.
See Also[edit]
References[edit]
<references />
