Involutional lipoatrophy: Difference between revisions
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{{Infobox medical condition | |||
| name = Involutional lipoatrophy | |||
| synonyms = | |||
| specialty = [[Dermatology]] | |||
| symptoms = Loss of [[subcutaneous fat]], skin [[depression (geology)|depressions]] | |||
| onset = Middle age | |||
| duration = Chronic | |||
| causes = Unknown | |||
| risks = | |||
| diagnosis = [[Clinical diagnosis]] | |||
| differential = [[Localized scleroderma]], [[Lipodystrophy]] | |||
| treatment = [[Dermal fillers]], [[fat grafting]] | |||
| prognosis = Variable | |||
| frequency = Rare | |||
}} | |||
'''Involutional lipoatrophy''' is a rare [[dermatological]] condition characterized by the loss of [[subcutaneous fat]] in certain areas of the body. The condition is often associated with [[autoimmune diseases]], [[diabetes]], and [[HIV/AIDS]], but can also occur independently. | '''Involutional lipoatrophy''' is a rare [[dermatological]] condition characterized by the loss of [[subcutaneous fat]] in certain areas of the body. The condition is often associated with [[autoimmune diseases]], [[diabetes]], and [[HIV/AIDS]], but can also occur independently. | ||
==Etiology== | ==Etiology== | ||
The exact cause of involutional lipoatrophy is unknown, but it is believed to be related to an abnormal immune response. Some researchers suggest that the condition may be triggered by an autoimmune reaction, in which the body's immune system mistakenly attacks its own tissues. Other possible causes include metabolic disorders, such as diabetes, and viral infections, such as HIV/AIDS. | The exact cause of involutional lipoatrophy is unknown, but it is believed to be related to an abnormal immune response. Some researchers suggest that the condition may be triggered by an autoimmune reaction, in which the body's immune system mistakenly attacks its own tissues. Other possible causes include metabolic disorders, such as diabetes, and viral infections, such as HIV/AIDS. | ||
==Symptoms== | ==Symptoms== | ||
The primary symptom of involutional lipoatrophy is the loss of subcutaneous fat, which can lead to changes in the appearance of the skin. This can result in a variety of symptoms, including: | The primary symptom of involutional lipoatrophy is the loss of subcutaneous fat, which can lead to changes in the appearance of the skin. This can result in a variety of symptoms, including: | ||
* [[Skin atrophy]]: The skin may appear thin and wrinkled, similar to the skin of an elderly person. | * [[Skin atrophy]]: The skin may appear thin and wrinkled, similar to the skin of an elderly person. | ||
* [[Depression (mood)|Depression]]: The changes in appearance can lead to feelings of depression and low self-esteem. | * [[Depression (mood)|Depression]]: The changes in appearance can lead to feelings of depression and low self-esteem. | ||
* [[Pain]]: Some people with involutional lipoatrophy experience pain in the affected areas. | * [[Pain]]: Some people with involutional lipoatrophy experience pain in the affected areas. | ||
==Diagnosis== | ==Diagnosis== | ||
Diagnosis of involutional lipoatrophy is typically based on the patient's medical history and a physical examination. In some cases, a [[biopsy]] may be performed to confirm the diagnosis and rule out other conditions. | Diagnosis of involutional lipoatrophy is typically based on the patient's medical history and a physical examination. In some cases, a [[biopsy]] may be performed to confirm the diagnosis and rule out other conditions. | ||
==Treatment== | ==Treatment== | ||
There is currently no cure for involutional lipoatrophy, but treatment can help manage the symptoms. Treatment options may include: | There is currently no cure for involutional lipoatrophy, but treatment can help manage the symptoms. Treatment options may include: | ||
* [[Corticosteroids]]: These medications can help reduce inflammation and slow the progression of the disease. | * [[Corticosteroids]]: These medications can help reduce inflammation and slow the progression of the disease. | ||
* [[Physical therapy]]: This can help improve mobility and reduce pain. | * [[Physical therapy]]: This can help improve mobility and reduce pain. | ||
* [[Cosmetic surgery]]: In some cases, cosmetic surgery may be recommended to improve the appearance of the skin. | * [[Cosmetic surgery]]: In some cases, cosmetic surgery may be recommended to improve the appearance of the skin. | ||
==See also== | ==See also== | ||
* [[Lipoatrophy]] | * [[Lipoatrophy]] | ||
* [[Lipodystrophy]] | * [[Lipodystrophy]] | ||
| Line 32: | Line 36: | ||
* [[Diabetes]] | * [[Diabetes]] | ||
* [[HIV/AIDS]] | * [[HIV/AIDS]] | ||
[[Category:Dermatology]] | [[Category:Dermatology]] | ||
[[Category:Rare diseases]] | [[Category:Rare diseases]] | ||
| Line 43: | Line 46: | ||
{{Diabetes-stub}} | {{Diabetes-stub}} | ||
{{HIV/AIDS-stub}} | {{HIV/AIDS-stub}} | ||
{{No image}} | |||
Latest revision as of 03:14, 4 April 2025
| Involutional lipoatrophy | |
|---|---|
| Synonyms | |
| Pronounce | N/A |
| Specialty | Dermatology |
| Symptoms | Loss of subcutaneous fat, skin depressions |
| Complications | N/A |
| Onset | Middle age |
| Duration | Chronic |
| Types | N/A |
| Causes | Unknown |
| Risks | |
| Diagnosis | Clinical diagnosis |
| Differential diagnosis | Localized scleroderma, Lipodystrophy |
| Prevention | N/A |
| Treatment | Dermal fillers, fat grafting |
| Medication | N/A |
| Prognosis | Variable |
| Frequency | Rare |
| Deaths | N/A |
Involutional lipoatrophy is a rare dermatological condition characterized by the loss of subcutaneous fat in certain areas of the body. The condition is often associated with autoimmune diseases, diabetes, and HIV/AIDS, but can also occur independently.
Etiology[edit]
The exact cause of involutional lipoatrophy is unknown, but it is believed to be related to an abnormal immune response. Some researchers suggest that the condition may be triggered by an autoimmune reaction, in which the body's immune system mistakenly attacks its own tissues. Other possible causes include metabolic disorders, such as diabetes, and viral infections, such as HIV/AIDS.
Symptoms[edit]
The primary symptom of involutional lipoatrophy is the loss of subcutaneous fat, which can lead to changes in the appearance of the skin. This can result in a variety of symptoms, including:
- Skin atrophy: The skin may appear thin and wrinkled, similar to the skin of an elderly person.
- Depression: The changes in appearance can lead to feelings of depression and low self-esteem.
- Pain: Some people with involutional lipoatrophy experience pain in the affected areas.
Diagnosis[edit]
Diagnosis of involutional lipoatrophy is typically based on the patient's medical history and a physical examination. In some cases, a biopsy may be performed to confirm the diagnosis and rule out other conditions.
Treatment[edit]
There is currently no cure for involutional lipoatrophy, but treatment can help manage the symptoms. Treatment options may include:
- Corticosteroids: These medications can help reduce inflammation and slow the progression of the disease.
- Physical therapy: This can help improve mobility and reduce pain.
- Cosmetic surgery: In some cases, cosmetic surgery may be recommended to improve the appearance of the skin.
See also[edit]

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