Carazolol: Difference between revisions
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'''Carazolol''' is a [[beta | {{Short description|A beta-adrenergic antagonist used in veterinary medicine}} | ||
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| image_alt = Structural formula of Carazolol | |||
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'''Carazolol''' is a non-selective [[beta-adrenergic antagonist]] primarily used in [[veterinary medicine]]. It is known for its high affinity for beta-adrenergic receptors and is utilized in various animal species to manage stress and improve meat quality. | |||
==Pharmacology== | ==Pharmacology== | ||
Carazolol | Carazolol acts by blocking the action of [[catecholamines]] such as [[epinephrine]] and [[norepinephrine]] on beta-adrenergic receptors. This action results in decreased heart rate and reduced cardiac output, which can be beneficial in managing stress responses in animals. | ||
== | ===Mechanism of Action=== | ||
Carazolol | Carazolol binds to beta-adrenergic receptors, preventing the binding of endogenous catecholamines. This blockade leads to a decrease in the activation of [[adenylate cyclase]], reducing the conversion of [[ATP]] to [[cAMP]], and ultimately decreasing the physiological effects mediated by beta-adrenergic stimulation. | ||
== | ==Uses in Veterinary Medicine== | ||
Carazolol is used in various animal species, including [[pigs]], [[cattle]], and [[poultry]], to manage stress during transport and slaughter. It helps in reducing the incidence of [[stress-related conditions]] such as [[porcine stress syndrome]] and improves meat quality by minimizing [[glycogen depletion]] and [[lactic acid]] accumulation in muscles. | |||
== | ==Side Effects== | ||
While carazolol is generally well-tolerated in animals, potential side effects include bradycardia, hypotension, and respiratory distress. Careful dosing and monitoring are essential to minimize adverse effects. | |||
== | ==Regulatory Status== | ||
Carazolol is approved for use in veterinary medicine in several countries. However, its use is subject to strict regulations to ensure animal welfare and food safety. | |||
==Related pages== | |||
* [[Beta blocker]] | * [[Beta blocker]] | ||
* [[ | * [[Adrenergic receptor]] | ||
* [[ | * [[Veterinary medicine]] | ||
[[Category:Beta blockers]] | [[Category:Beta blockers]] | ||
[[Category: | [[Category:Veterinary drugs]] | ||
<gallery> | |||
File:Carazolol.svg|Carazolol | |||
</gallery> | |||
Latest revision as of 00:55, 20 February 2025
A beta-adrenergic antagonist used in veterinary medicine
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Carazolol is a non-selective beta-adrenergic antagonist primarily used in veterinary medicine. It is known for its high affinity for beta-adrenergic receptors and is utilized in various animal species to manage stress and improve meat quality.
Pharmacology[edit]
Carazolol acts by blocking the action of catecholamines such as epinephrine and norepinephrine on beta-adrenergic receptors. This action results in decreased heart rate and reduced cardiac output, which can be beneficial in managing stress responses in animals.
Mechanism of Action[edit]
Carazolol binds to beta-adrenergic receptors, preventing the binding of endogenous catecholamines. This blockade leads to a decrease in the activation of adenylate cyclase, reducing the conversion of ATP to cAMP, and ultimately decreasing the physiological effects mediated by beta-adrenergic stimulation.
Uses in Veterinary Medicine[edit]
Carazolol is used in various animal species, including pigs, cattle, and poultry, to manage stress during transport and slaughter. It helps in reducing the incidence of stress-related conditions such as porcine stress syndrome and improves meat quality by minimizing glycogen depletion and lactic acid accumulation in muscles.
Side Effects[edit]
While carazolol is generally well-tolerated in animals, potential side effects include bradycardia, hypotension, and respiratory distress. Careful dosing and monitoring are essential to minimize adverse effects.
Regulatory Status[edit]
Carazolol is approved for use in veterinary medicine in several countries. However, its use is subject to strict regulations to ensure animal welfare and food safety.
Related pages[edit]
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Carazolol
