Mucus

Mucus is a slippery aqueous secretion produced by, and covering, mucous membranes. It is typically produced from cells found in the mucous gland, but it can also originate from mixed glands, which contain both serous and mucus cells. This mucus serves to protect epithelial cells in the respiratory, gastrointestinal, urogenital, visual, and auditory systems; the epidermis in amphibians; and the gills in fish.

Composition

Mucus is composed of water, epithelial cells, dead leukocytes, mucin, and inorganic salts. Mucins are a type of protein that are heavily glycosylated. The glycans attached to the mucins attract water, which makes the mucus gel-like and resistant to deformation.

Functions

Mucus serves several functions, such as trapping dust particles and bacteria in the respiratory system, preventing the body from drying out, and lubricating the passage of materials through the body's various tracts.

Clinical significance

In pathology, mucus can be a sign of certain diseases, including Cystic fibrosis, Chronic bronchitis, and Irritable bowel syndrome. In these conditions, the body overproduces mucus, which can lead to discomfort and other symptoms.

See also

• Mucous membrane
• Mucin
• Cystic fibrosis
• Chronic bronchitis
• Irritable bowel syndrome

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