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'''Lockwood's sign''' is a clinical sign in which there is excessive skin on the upper eyelid (dermatochalasis) that can be stretched away from the eye, then snaps back into place when released. This sign is often associated with [[Graves' disease]], an autoimmune disorder that causes hyperthyroidism, or overactive thyroid.


{{Infobox medical condition
| name            = Lockwood's sign
| synonyms        =
| specialty      = [[Ophthalmology]]
| symptoms        = [[Ptosis (eyelid)|Ptosis]], [[Enophthalmos]]
| causes          = [[Horner's syndrome]]
| diagnosis      = Clinical examination
| differential    = [[Myasthenia gravis]], [[Third nerve palsy]]
| treatment      = Treat underlying cause
| prognosis      = Depends on underlying condition
| frequency      = Rare
}}
```
This template provides a structured summary of the medical condition known as Lockwood's sign, which is associated with certain ophthalmological symptoms and conditions. It is important for medical students to understand the clinical presentation, potential causes, and differential diagnoses when evaluating a patient with this sign. '''Lockwood's sign''' is a clinical sign in which there is excessive skin on the upper eyelid (dermatochalasis) that can be stretched away from the eye, then snaps back into place when released. This sign is often associated with [[Graves' disease]], an autoimmune disorder that causes hyperthyroidism, or overactive thyroid.
== Causes ==
== Causes ==
The primary cause of Lockwood's sign is [[Graves' disease]]. This autoimmune disorder leads to an overactive thyroid, a condition known as hyperthyroidism. The disease can cause a variety of symptoms, including weight loss, rapid heart rate, and anxiety. One of the most distinctive signs of Graves' disease is changes to the eyes, including swelling and inflammation, that can lead to Lockwood's sign.
The primary cause of Lockwood's sign is [[Graves' disease]]. This autoimmune disorder leads to an overactive thyroid, a condition known as hyperthyroidism. The disease can cause a variety of symptoms, including weight loss, rapid heart rate, and anxiety. One of the most distinctive signs of Graves' disease is changes to the eyes, including swelling and inflammation, that can lead to Lockwood's sign.
== Symptoms ==
== Symptoms ==
The main symptom of Lockwood's sign is excessive skin on the upper eyelid that can be stretched away from the eye. This skin then snaps back into place when released. Other symptoms can include redness, swelling, and a feeling of grittiness in the eyes. Some people may also experience double vision or other vision problems.
The main symptom of Lockwood's sign is excessive skin on the upper eyelid that can be stretched away from the eye. This skin then snaps back into place when released. Other symptoms can include redness, swelling, and a feeling of grittiness in the eyes. Some people may also experience double vision or other vision problems.
== Diagnosis ==
== Diagnosis ==
Lockwood's sign is typically diagnosed during a physical examination. A doctor may also order blood tests to check for the presence of certain antibodies that are often present in people with Graves' disease.
Lockwood's sign is typically diagnosed during a physical examination. A doctor may also order blood tests to check for the presence of certain antibodies that are often present in people with Graves' disease.
== Treatment ==
== Treatment ==
Treatment for Lockwood's sign typically involves addressing the underlying cause, which is often Graves' disease. This can include medication to regulate the thyroid, as well as treatments to reduce inflammation and swelling in the eyes.
Treatment for Lockwood's sign typically involves addressing the underlying cause, which is often Graves' disease. This can include medication to regulate the thyroid, as well as treatments to reduce inflammation and swelling in the eyes.
== See also ==
== See also ==
* [[Graves' disease]]
* [[Graves' disease]]
* [[Hyperthyroidism]]
* [[Hyperthyroidism]]
* [[Eye disease]]
* [[Eye disease]]
== References ==
== References ==
<references />
<references />
[[Category:Medical signs]]
[[Category:Medical signs]]
[[Category:Ophthalmology]]
[[Category:Ophthalmology]]
[[Category:Endocrinology]]
[[Category:Endocrinology]]
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Latest revision as of 04:12, 4 April 2025


Lockwood's sign
Synonyms
Pronounce N/A
Specialty Ophthalmology
Symptoms Ptosis, Enophthalmos
Complications N/A
Onset N/A
Duration N/A
Types N/A
Causes Horner's syndrome
Risks N/A
Diagnosis Clinical examination
Differential diagnosis Myasthenia gravis, Third nerve palsy
Prevention N/A
Treatment Treat underlying cause
Medication N/A
Prognosis Depends on underlying condition
Frequency Rare
Deaths N/A


``` This template provides a structured summary of the medical condition known as Lockwood's sign, which is associated with certain ophthalmological symptoms and conditions. It is important for medical students to understand the clinical presentation, potential causes, and differential diagnoses when evaluating a patient with this sign. Lockwood's sign is a clinical sign in which there is excessive skin on the upper eyelid (dermatochalasis) that can be stretched away from the eye, then snaps back into place when released. This sign is often associated with Graves' disease, an autoimmune disorder that causes hyperthyroidism, or overactive thyroid.

Causes[edit]

The primary cause of Lockwood's sign is Graves' disease. This autoimmune disorder leads to an overactive thyroid, a condition known as hyperthyroidism. The disease can cause a variety of symptoms, including weight loss, rapid heart rate, and anxiety. One of the most distinctive signs of Graves' disease is changes to the eyes, including swelling and inflammation, that can lead to Lockwood's sign.

Symptoms[edit]

The main symptom of Lockwood's sign is excessive skin on the upper eyelid that can be stretched away from the eye. This skin then snaps back into place when released. Other symptoms can include redness, swelling, and a feeling of grittiness in the eyes. Some people may also experience double vision or other vision problems.

Diagnosis[edit]

Lockwood's sign is typically diagnosed during a physical examination. A doctor may also order blood tests to check for the presence of certain antibodies that are often present in people with Graves' disease.

Treatment[edit]

Treatment for Lockwood's sign typically involves addressing the underlying cause, which is often Graves' disease. This can include medication to regulate the thyroid, as well as treatments to reduce inflammation and swelling in the eyes.

See also[edit]

References[edit]

<references />

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