Enterocyte: Difference between revisions

From WikiMD's Wellness Encyclopedia

CSV import
Tags: mobile edit mobile web edit
 
CSV import
 
Line 1: Line 1:
'''Enterocyte'''
{{DISPLAYTITLE:Enterocyte}}


An '''enterocyte''' is a cell of the intestinal lining. It is a type of [[epithelial cell]] that is specialized for absorbing nutrients from the lumen of the intestine into the bloodstream. Enterocytes are found in the [[small intestine]], where they play a crucial role in digestion and absorption of food.
== Overview ==
[[File:Cell_enterocyte.png|thumb|right|Diagram of an enterocyte]]
An '''enterocyte''' is a type of cell found in the [[small intestine]] and is primarily responsible for the absorption of nutrients. These cells line the inner surface of the intestine and play a crucial role in the [[digestive system]]. Enterocytes are a type of [[epithelial cell]] and are characterized by their brush border, which is composed of [[microvilli]].


==Structure==
== Structure ==
Enterocytes are tall, columnar cells that are specialized for absorption. The apical surface of an enterocyte is covered with microvilli, which increase the surface area for absorption. This brush border is rich in enzymes that aid in the digestion of nutrients. The lateral surfaces of enterocytes are connected by [[tight junctions]], which help maintain the integrity of the intestinal barrier.


Enterocytes are columnar in shape and have a brush border of microvilli on their apical surface. This increases the surface area for absorption. The cells are joined together by [[tight junctions]], which prevent the passage of substances between the cells.
== Function ==
The primary function of enterocytes is the absorption of nutrients from the intestinal lumen. They absorb [[amino acids]], [[monosaccharides]], [[fatty acids]], and other nutrients, which are then transported into the bloodstream. Enterocytes also play a role in the secretion of digestive enzymes and in the immune response of the gut.


==Function==
== Life Cycle ==
Enterocytes have a rapid turnover rate, with a lifespan of only a few days. They are continuously renewed from [[stem cells]] located in the [[crypts of Lieberkühn]] at the base of the intestinal villi. As new enterocytes are produced, older cells are shed into the intestinal lumen.


The primary function of enterocytes is to absorb nutrients from the food we eat. They do this by transporting nutrients across their cell membrane and into the bloodstream. This includes the absorption of [[carbohydrates]], [[proteins]], [[fats]], [[vitamins]], and [[minerals]].
== Clinical Significance ==
Damage to enterocytes can lead to malabsorption syndromes, where the body is unable to absorb nutrients effectively. Conditions such as [[celiac disease]], [[Crohn's disease]], and [[intestinal infections]] can affect the function and integrity of enterocytes.


Enterocytes also have a role in the immune system. They can recognize and respond to pathogens in the gut, and they help to maintain the balance of the gut microbiota.
== Related pages ==
* [[Small intestine]]
* [[Digestive system]]
* [[Microvilli]]
* [[Epithelial cell]]


==Clinical significance==
[[Category:Cell biology]]
 
Diseases that affect the enterocytes can lead to malabsorption of nutrients, which can cause a variety of symptoms such as weight loss, diarrhea, and nutritional deficiencies. Examples of such diseases include [[celiac disease]], [[Crohn's disease]], and [[short bowel syndrome]].
 
==See also==
 
* [[Gastrointestinal tract]]
* [[Digestion]]
* [[Nutrient absorption]]
* [[Epithelial cells]]
 
==References==
 
<references />
 
[[Category:Anatomy]]
[[Category:Digestive system]]
[[Category:Digestive system]]
[[Category:Cells]]
{{stub}}

Latest revision as of 10:47, 15 February 2025


Overview[edit]

Diagram of an enterocyte

An enterocyte is a type of cell found in the small intestine and is primarily responsible for the absorption of nutrients. These cells line the inner surface of the intestine and play a crucial role in the digestive system. Enterocytes are a type of epithelial cell and are characterized by their brush border, which is composed of microvilli.

Structure[edit]

Enterocytes are tall, columnar cells that are specialized for absorption. The apical surface of an enterocyte is covered with microvilli, which increase the surface area for absorption. This brush border is rich in enzymes that aid in the digestion of nutrients. The lateral surfaces of enterocytes are connected by tight junctions, which help maintain the integrity of the intestinal barrier.

Function[edit]

The primary function of enterocytes is the absorption of nutrients from the intestinal lumen. They absorb amino acids, monosaccharides, fatty acids, and other nutrients, which are then transported into the bloodstream. Enterocytes also play a role in the secretion of digestive enzymes and in the immune response of the gut.

Life Cycle[edit]

Enterocytes have a rapid turnover rate, with a lifespan of only a few days. They are continuously renewed from stem cells located in the crypts of Lieberkühn at the base of the intestinal villi. As new enterocytes are produced, older cells are shed into the intestinal lumen.

Clinical Significance[edit]

Damage to enterocytes can lead to malabsorption syndromes, where the body is unable to absorb nutrients effectively. Conditions such as celiac disease, Crohn's disease, and intestinal infections can affect the function and integrity of enterocytes.

Related pages[edit]