Dichloropane: Difference between revisions
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{{DISPLAYTITLE:Dichloropane}} | |||
== | == Overview == | ||
'''Dichloropane''' is a synthetic stimulant drug of the [[phenyltropane]] class. It is a potent [[dopamine reuptake inhibitor]], which means it increases the levels of [[dopamine]] in the brain by preventing its reabsorption into neurons. This action is similar to that of [[cocaine]], although dichloropane is structurally distinct. | |||
== | == Chemical Structure == | ||
[[File:Phenyltropane_17c.svg|thumb|right|Chemical structure of Dichloropane]] | |||
Dichloropane is chemically known as 2_-carbomethoxy-3_-(3,4-dichlorophenyl)tropane. It belongs to the phenyltropane family, which are analogs of [[tropane]] alkaloids. The presence of the dichlorophenyl group is a key feature that distinguishes it from other phenyltropanes. | |||
== | == Pharmacology == | ||
Dichloropane | Dichloropane acts primarily as a [[dopamine reuptake inhibitor]], but it also affects the reuptake of [[serotonin]] and [[norepinephrine]] to a lesser extent. This broad spectrum of activity contributes to its stimulant effects. The inhibition of dopamine reuptake leads to increased concentrations of dopamine in the synaptic cleft, enhancing dopaminergic neurotransmission. | ||
== | == Effects == | ||
The effects of dichloropane are similar to those of other stimulants, including increased alertness, euphoria, and enhanced cognitive performance. However, it also carries risks of adverse effects such as anxiety, paranoia, and potential for addiction due to its impact on the brain's reward system. | |||
== | == Synthesis == | ||
The synthesis of dichloropane involves the modification of the tropane ring system, typically starting from tropinone. The introduction of the dichlorophenyl group is a critical step in the synthesis, which requires careful control of reaction conditions to achieve the desired stereochemistry. | |||
== | == Legal Status == | ||
The legal status of dichloropane varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of accepted medical use. | |||
== Related Compounds == | |||
Dichloropane is related to other phenyltropanes such as [[RTI-55]] and [[RTI-31]], which also act as dopamine reuptake inhibitors. These compounds are often studied for their potential use in treating disorders such as [[ADHD]] and [[narcolepsy]], although their stimulant properties pose challenges for therapeutic use. | |||
== See Also == | |||
* [[Cocaine]] | |||
* [[Dopamine reuptake inhibitor]] | |||
* [[Phenyltropane]] | |||
* [[Stimulant]] | |||
== Related Pages == | |||
* [[Tropane alkaloid]] | |||
* [[Neurotransmitter]] | |||
* [[Addiction]] | |||
[[Category:Stimulants]] | [[Category:Stimulants]] | ||
[[Category:Phenyltropanes]] | [[Category:Phenyltropanes]] | ||
Latest revision as of 11:28, 15 February 2025
Overview[edit]
Dichloropane is a synthetic stimulant drug of the phenyltropane class. It is a potent dopamine reuptake inhibitor, which means it increases the levels of dopamine in the brain by preventing its reabsorption into neurons. This action is similar to that of cocaine, although dichloropane is structurally distinct.
Chemical Structure[edit]
Dichloropane is chemically known as 2_-carbomethoxy-3_-(3,4-dichlorophenyl)tropane. It belongs to the phenyltropane family, which are analogs of tropane alkaloids. The presence of the dichlorophenyl group is a key feature that distinguishes it from other phenyltropanes.
Pharmacology[edit]
Dichloropane acts primarily as a dopamine reuptake inhibitor, but it also affects the reuptake of serotonin and norepinephrine to a lesser extent. This broad spectrum of activity contributes to its stimulant effects. The inhibition of dopamine reuptake leads to increased concentrations of dopamine in the synaptic cleft, enhancing dopaminergic neurotransmission.
Effects[edit]
The effects of dichloropane are similar to those of other stimulants, including increased alertness, euphoria, and enhanced cognitive performance. However, it also carries risks of adverse effects such as anxiety, paranoia, and potential for addiction due to its impact on the brain's reward system.
Synthesis[edit]
The synthesis of dichloropane involves the modification of the tropane ring system, typically starting from tropinone. The introduction of the dichlorophenyl group is a critical step in the synthesis, which requires careful control of reaction conditions to achieve the desired stereochemistry.
Legal Status[edit]
The legal status of dichloropane varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of accepted medical use.
Related Compounds[edit]
Dichloropane is related to other phenyltropanes such as RTI-55 and RTI-31, which also act as dopamine reuptake inhibitors. These compounds are often studied for their potential use in treating disorders such as ADHD and narcolepsy, although their stimulant properties pose challenges for therapeutic use.
