Growth hormone therapy: Difference between revisions

Latest revision as of 04:27, 29 December 2024

Medical treatment involving the use of growth hormone

Growth hormone therapy

Growth hormone therapy refers to the use of growth hormone (GH) as a prescription medication. It is used to treat children and adults with growth hormone deficiency (GHD) and other conditions that result in short stature or poor growth.

Indications[edit]

Growth hormone therapy is indicated for several conditions, including:

Growth hormone deficiency in children and adults
Turner syndrome
Chronic kidney disease
Prader-Willi syndrome
Small for gestational age
Idiopathic short stature

Mechanism of Action[edit]

Growth hormone stimulates growth, cell reproduction, and cell regeneration in humans. It is a peptide hormone that stimulates the liver and other tissues to secrete insulin-like growth factor 1 (IGF-1), which in turn promotes growth in bones and other tissues.

Administration[edit]

Growth hormone is typically administered via subcutaneous injection. The dosage and frequency depend on the condition being treated, the patient's age, and their response to therapy.

Side Effects[edit]

Common side effects of growth hormone therapy include:

Joint pain
Muscle pain
Edema (swelling due to fluid retention)
Carpal tunnel syndrome
Increased risk of diabetes mellitus

Controversy and Misuse[edit]

Growth hormone therapy has been controversial due to its misuse in sports doping and anti-aging treatments. The use of growth hormone for these purposes is not approved by regulatory agencies and can have significant health risks.

References[edit]

External Links[edit]

@@ Line 1: / Line 1: @@
-== Growth Hormone Therapy ==
+{{Short description|Medical treatment involving the use of growth hormone}}
+{{Use dmy dates|date=October 2023}}
+{{Infobox medical treatment
+| name             = Growth hormone therapy
+| image            = <!-- Image removed -->
+| caption          = <!-- Caption removed -->
+| synonyms         = Human growth hormone therapy
+| ICD10            = {{ICD10|E23.0}}
+| ICD9             = {{ICD9|253.3}}
+| MeshID           = D006406
+| MedlinePlus     = 003367
+}}
-[[File:Growth hormone structure.png|thumb|right|250px|Structure of the growth hormone]]
+'''Growth hormone therapy''' refers to the use of [[growth hormone]] (GH) as a prescription medication. It is used to treat children and adults with [[growth hormone deficiency]] (GHD) and other conditions that result in short stature or poor growth.
-'''Growth hormone therapy''' refers to the use of [[growth hormone]] (GH) as a prescription medication to treat children and adults with GH deficiency and other conditions.
+== Indications ==
+Growth hormone therapy is indicated for several conditions, including:
+* [[Growth hormone deficiency]] in children and adults
+* [[Turner syndrome]]
+* [[Chronic kidney disease]]
+* [[Prader-Willi syndrome]]
+* [[Small for gestational age]]
+* [[Idiopathic short stature]]
-== Overview ==
+== Mechanism of Action ==
+Growth hormone stimulates growth, cell reproduction, and cell regeneration in humans. It is a [[peptide hormone]] that stimulates the [[liver]] and other tissues to secrete [[insulin-like growth factor 1]] (IGF-1), which in turn promotes growth in bones and other tissues.
-Growth hormone, also known as somatotropin, is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration in humans and other animals. It is thus crucial in human development. GH also stimulates the production of [[Insulin-like growth factor 1|IGF-1]], a hormone similar to insulin that plays an important role in childhood growth and continues to have anabolic effects in adults.
+== Administration ==
+Growth hormone is typically administered via [[subcutaneous injection]]. The dosage and frequency depend on the condition being treated, the patient's age, and their response to therapy.
-== Medical Uses ==
-Growth hormone therapy is used to treat conditions that cause short stature in children, and to replace GH in adults with GH deficiency.
-=== Children ===
-In children, growth hormone is approved for the treatment of poor growth due to Turner syndrome, Prader-Willi syndrome, chronic kidney disease, HGH deficiency or insufficiency, short stature homeobox-containing gene (SHOX) deficiency, and for children born small for gestational age (SGA) with no catch-up growth by age 2 to 4 years of age.
-=== Adults ===
-In adults, approved uses of HGH include short bowel syndrome and HGH deficiency due to rare pituitary tumors or their treatment. It is also used to prevent HIV/AIDS wasting syndrome.
 == Side Effects ==
+Common side effects of growth hormone therapy include:
+* [[Joint pain]]
+* [[Muscle pain]]
+* [[Edema]] (swelling due to fluid retention)
+* [[Carpal tunnel syndrome]]
+* Increased risk of [[diabetes mellitus]]
-Like all medicines, growth hormone therapy can cause side effects, although not everybody gets them. These can include joint pain, muscle pain, carpal tunnel syndrome, increased insulin resistance, and increased risk of diabetes.
+== Controversy and Misuse ==
+Growth hormone therapy has been controversial due to its misuse in [[sports doping]] and [[anti-aging]] treatments. The use of growth hormone for these purposes is not approved by regulatory agencies and can have significant health risks.
 == See Also ==
 * [[Endocrinology]]
-* [[Pediatrics]]
+* [[Hormone replacement therapy]]
-* [[Hormone replacement therapy (menopause)]]
+* [[Pediatric endocrinology]]
 == References ==
+{{Reflist}}
-<references />
+== External Links ==
+* [https://www.endocrine.org/topics/growth-hormone Endocrine Society: Growth Hormone]
+* [https://www.hormone.org/diseases-and-conditions/growth-disorders Hormone Health Network: Growth Disorders]
+{{DEFAULTSORT:Growth Hormone Therapy}}
 [[Category:Endocrinology]]
+[[Category:Hormone therapy]]
 [[Category:Pediatrics]]
-[[Category:Hormone replacement therapy]]
+[[Category:Medical treatments]]
-[[Category:Growth hormones]]