Subacute cutaneous lupus erythematosus: Difference between revisions
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{{Infobox medical condition | |||
| name = Subacute cutaneous lupus erythematosus | |||
| synonyms = SCLE | |||
| field = [[Rheumatology]], [[Dermatology]] | |||
| symptoms = [[Skin rash]], [[photosensitivity]], [[arthralgia]] | |||
| complications = [[Systemic lupus erythematosus]], [[nephritis]] | |||
| onset = Typically between ages 15 and 50 | |||
| duration = Chronic | |||
| causes = [[Autoimmune disease]] | |||
| risks = [[Genetic predisposition]], [[ultraviolet light]] exposure, certain [[medications]] | |||
| diagnosis = [[Clinical examination]], [[skin biopsy]], [[serological tests]] | |||
| differential = [[Psoriasis]], [[eczema]], [[rosacea]] | |||
| treatment = [[Topical corticosteroids]], [[antimalarials]], [[immunosuppressants]] | |||
| medication = [[Hydroxychloroquine]], [[methotrexate]], [[prednisone]] | |||
| prognosis = Variable, can be managed with treatment | |||
| frequency = Rare | |||
}} | |||
'''Subacute cutaneous lupus erythematosus''' (SCLE) is a subtype of [[lupus erythematosus]], an autoimmune disease. It is characterized by skin lesions that appear on areas of the body exposed to the sun. The lesions may be either annular (ring-shaped) or psoriasiform (resembling psoriasis). | '''Subacute cutaneous lupus erythematosus''' (SCLE) is a subtype of [[lupus erythematosus]], an autoimmune disease. It is characterized by skin lesions that appear on areas of the body exposed to the sun. The lesions may be either annular (ring-shaped) or psoriasiform (resembling psoriasis). | ||
== Signs and Symptoms == | == Signs and Symptoms == | ||
Patients with SCLE typically present with skin lesions that are either annular or psoriasiform. These lesions are photosensitive, meaning they worsen with exposure to sunlight. Other symptoms may include fatigue, joint pain, and fever. | Patients with SCLE typically present with skin lesions that are either annular or psoriasiform. These lesions are photosensitive, meaning they worsen with exposure to sunlight. Other symptoms may include fatigue, joint pain, and fever. | ||
== Causes == | == Causes == | ||
The exact cause of SCLE is unknown, but it is believed to be an autoimmune disorder. This means that the body's immune system mistakenly attacks healthy tissue. Certain factors may trigger the onset of the disease, such as exposure to sunlight, certain medications, and viral infections. | The exact cause of SCLE is unknown, but it is believed to be an autoimmune disorder. This means that the body's immune system mistakenly attacks healthy tissue. Certain factors may trigger the onset of the disease, such as exposure to sunlight, certain medications, and viral infections. | ||
== Diagnosis == | == Diagnosis == | ||
Diagnosis of SCLE is based on the patient's clinical presentation and laboratory tests. A skin biopsy may be performed to confirm the diagnosis. Blood tests may reveal the presence of certain antibodies that are commonly found in patients with SCLE. | Diagnosis of SCLE is based on the patient's clinical presentation and laboratory tests. A skin biopsy may be performed to confirm the diagnosis. Blood tests may reveal the presence of certain antibodies that are commonly found in patients with SCLE. | ||
== Treatment == | == Treatment == | ||
Treatment for SCLE typically involves avoiding sun exposure and using sun-protective measures. Medications may also be prescribed to manage symptoms and prevent flare-ups. These may include topical corticosteroids, antimalarial drugs, and immunosuppressive agents. | Treatment for SCLE typically involves avoiding sun exposure and using sun-protective measures. Medications may also be prescribed to manage symptoms and prevent flare-ups. These may include topical corticosteroids, antimalarial drugs, and immunosuppressive agents. | ||
== Prognosis == | == Prognosis == | ||
The prognosis for patients with SCLE is generally good, as the disease is usually less severe than other forms of lupus erythematosus. However, patients may experience periods of remission and relapse. | The prognosis for patients with SCLE is generally good, as the disease is usually less severe than other forms of lupus erythematosus. However, patients may experience periods of remission and relapse. | ||
== See Also == | == See Also == | ||
* [[Lupus erythematosus]] | * [[Lupus erythematosus]] | ||
| Line 22: | Line 34: | ||
* [[Corticosteroids]] | * [[Corticosteroids]] | ||
* [[Antimalarial drugs]] | * [[Antimalarial drugs]] | ||
== References == | == References == | ||
<references /> | <references /> | ||
[[Category:Autoimmune diseases]] | [[Category:Autoimmune diseases]] | ||
[[Category:Skin conditions]] | [[Category:Skin conditions]] | ||
[[Category:Lupus]] | [[Category:Lupus]] | ||
{{stub}} | {{stub}} | ||
{{No image}} | {{No image}} | ||
Latest revision as of 03:21, 4 April 2025
| Subacute cutaneous lupus erythematosus | |
|---|---|
| Synonyms | SCLE |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Skin rash, photosensitivity, arthralgia |
| Complications | Systemic lupus erythematosus, nephritis |
| Onset | Typically between ages 15 and 50 |
| Duration | Chronic |
| Types | N/A |
| Causes | Autoimmune disease |
| Risks | Genetic predisposition, ultraviolet light exposure, certain medications |
| Diagnosis | Clinical examination, skin biopsy, serological tests |
| Differential diagnosis | Psoriasis, eczema, rosacea |
| Prevention | N/A |
| Treatment | Topical corticosteroids, antimalarials, immunosuppressants |
| Medication | Hydroxychloroquine, methotrexate, prednisone |
| Prognosis | Variable, can be managed with treatment |
| Frequency | Rare |
| Deaths | N/A |
Subacute cutaneous lupus erythematosus (SCLE) is a subtype of lupus erythematosus, an autoimmune disease. It is characterized by skin lesions that appear on areas of the body exposed to the sun. The lesions may be either annular (ring-shaped) or psoriasiform (resembling psoriasis).
Signs and Symptoms[edit]
Patients with SCLE typically present with skin lesions that are either annular or psoriasiform. These lesions are photosensitive, meaning they worsen with exposure to sunlight. Other symptoms may include fatigue, joint pain, and fever.
Causes[edit]
The exact cause of SCLE is unknown, but it is believed to be an autoimmune disorder. This means that the body's immune system mistakenly attacks healthy tissue. Certain factors may trigger the onset of the disease, such as exposure to sunlight, certain medications, and viral infections.
Diagnosis[edit]
Diagnosis of SCLE is based on the patient's clinical presentation and laboratory tests. A skin biopsy may be performed to confirm the diagnosis. Blood tests may reveal the presence of certain antibodies that are commonly found in patients with SCLE.
Treatment[edit]
Treatment for SCLE typically involves avoiding sun exposure and using sun-protective measures. Medications may also be prescribed to manage symptoms and prevent flare-ups. These may include topical corticosteroids, antimalarial drugs, and immunosuppressive agents.
Prognosis[edit]
The prognosis for patients with SCLE is generally good, as the disease is usually less severe than other forms of lupus erythematosus. However, patients may experience periods of remission and relapse.
See Also[edit]
References[edit]
<references />
