Diffuse neonatal hemangiomatosis: Difference between revisions

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{{Infobox medical condition
| name            = Diffuse neonatal hemangiomatosis
| synonyms        =
| image          =
| caption        =
| field          = [[Pediatrics]], [[Dermatology]]
| symptoms        = Multiple [[hemangiomas]] on skin and internal organs
| complications  = [[Heart failure]], [[anemia]], [[thrombocytopenia]]
| onset          = [[Neonatal]] period
| duration        = Varies
| causes          = Unknown
| risks          =
| diagnosis      = [[Clinical examination]], [[imaging studies]]
| differential    = [[Infantile hemangioma]], [[Kasabach-Merritt syndrome]]
| treatment      = [[Corticosteroids]], [[beta blockers]], [[interferon]]
| medication      =
| prognosis      = Variable, can be life-threatening
| frequency      = Rare
}}
'''Diffuse Neonatal Hemangiomatosis''' is a rare, severe disorder characterized by multiple [[hemangiomas]]. Hemangiomas are noncancerous (benign) growths consisting of a mass of blood vessels. They are the most common benign blood vessel (vascular) abnormalities of infancy.
'''Diffuse Neonatal Hemangiomatosis''' is a rare, severe disorder characterized by multiple [[hemangiomas]]. Hemangiomas are noncancerous (benign) growths consisting of a mass of blood vessels. They are the most common benign blood vessel (vascular) abnormalities of infancy.
== Signs and Symptoms ==
== Signs and Symptoms ==
The signs and symptoms of diffuse neonatal hemangiomatosis may vary but can include:
The signs and symptoms of diffuse neonatal hemangiomatosis may vary but can include:
* Multiple, small, red or reddish-purple [[skin lesion|skin lesions]] on the skin
* Multiple, small, red or reddish-purple [[skin lesion|skin lesions]] on the skin
* Lesions may also be present on internal organs such as the [[liver]], [[lung]], [[brain]], and [[gastrointestinal tract]]
* Lesions may also be present on internal organs such as the [[liver]], [[lung]], [[brain]], and [[gastrointestinal tract]]
* Potential complications can include [[heart failure]] due to high-output cardiac failure, [[bleeding]] from lesions within the gastrointestinal tract, and/or other serious complications
* Potential complications can include [[heart failure]] due to high-output cardiac failure, [[bleeding]] from lesions within the gastrointestinal tract, and/or other serious complications
== Causes ==
== Causes ==
The exact cause of diffuse neonatal hemangiomatosis is currently unknown. However, it is thought to occur randomly for no apparent reason (sporadically).
The exact cause of diffuse neonatal hemangiomatosis is currently unknown. However, it is thought to occur randomly for no apparent reason (sporadically).
== Diagnosis ==
== Diagnosis ==
Diagnosis of diffuse neonatal hemangiomatosis is made based upon a thorough clinical evaluation, a detailed patient history, and specialized tests such as [[ultrasound]] imaging, [[magnetic resonance imaging]] (MRI), and/or other tests.
Diagnosis of diffuse neonatal hemangiomatosis is made based upon a thorough clinical evaluation, a detailed patient history, and specialized tests such as [[ultrasound]] imaging, [[magnetic resonance imaging]] (MRI), and/or other tests.
== Treatment ==
== Treatment ==
The treatment of diffuse neonatal hemangiomatosis is directed toward the specific symptoms that are apparent in each individual. Treatment may include [[corticosteroid]] therapy or [[interferon]] therapy. In severe cases, surgical removal of individual hemangiomas may be necessary.
The treatment of diffuse neonatal hemangiomatosis is directed toward the specific symptoms that are apparent in each individual. Treatment may include [[corticosteroid]] therapy or [[interferon]] therapy. In severe cases, surgical removal of individual hemangiomas may be necessary.
== See Also ==
== See Also ==
* [[Hemangioma]]
* [[Hemangioma]]
* [[Vascular birthmark]]
* [[Vascular birthmark]]
* [[Infantile Hemangioma]]
* [[Infantile Hemangioma]]
== References ==
== References ==
* [[National Organization for Rare Disorders (NORD)]]
* [[National Organization for Rare Disorders (NORD)]]
* [[Genetic and Rare Diseases Information Center (GARD)]]
* [[Genetic and Rare Diseases Information Center (GARD)]]
[[Category:Medical Conditions]]
[[Category:Medical Conditions]]
[[Category:Rare Diseases]]
[[Category:Rare Diseases]]
[[Category:Pediatrics]]
[[Category:Pediatrics]]
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Latest revision as of 03:12, 4 April 2025


Diffuse neonatal hemangiomatosis
Synonyms
Pronounce N/A
Specialty N/A
Symptoms Multiple hemangiomas on skin and internal organs
Complications Heart failure, anemia, thrombocytopenia
Onset Neonatal period
Duration Varies
Types N/A
Causes Unknown
Risks
Diagnosis Clinical examination, imaging studies
Differential diagnosis Infantile hemangioma, Kasabach-Merritt syndrome
Prevention N/A
Treatment Corticosteroids, beta blockers, interferon
Medication
Prognosis Variable, can be life-threatening
Frequency Rare
Deaths N/A


Diffuse Neonatal Hemangiomatosis is a rare, severe disorder characterized by multiple hemangiomas. Hemangiomas are noncancerous (benign) growths consisting of a mass of blood vessels. They are the most common benign blood vessel (vascular) abnormalities of infancy.

Signs and Symptoms[edit]

The signs and symptoms of diffuse neonatal hemangiomatosis may vary but can include:

  • Multiple, small, red or reddish-purple skin lesions on the skin
  • Lesions may also be present on internal organs such as the liver, lung, brain, and gastrointestinal tract
  • Potential complications can include heart failure due to high-output cardiac failure, bleeding from lesions within the gastrointestinal tract, and/or other serious complications

Causes[edit]

The exact cause of diffuse neonatal hemangiomatosis is currently unknown. However, it is thought to occur randomly for no apparent reason (sporadically).

Diagnosis[edit]

Diagnosis of diffuse neonatal hemangiomatosis is made based upon a thorough clinical evaluation, a detailed patient history, and specialized tests such as ultrasound imaging, magnetic resonance imaging (MRI), and/or other tests.

Treatment[edit]

The treatment of diffuse neonatal hemangiomatosis is directed toward the specific symptoms that are apparent in each individual. Treatment may include corticosteroid therapy or interferon therapy. In severe cases, surgical removal of individual hemangiomas may be necessary.

See Also[edit]

References[edit]

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