Neutrophilic lobular panniculitis: Difference between revisions
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{{Infobox medical condition | |||
| name = Neutrophilic lobular panniculitis | |||
| synonyms = | |||
| specialty = [[Dermatology]] | |||
| symptoms = [[Pain]], [[tenderness]], [[erythema]], [[nodules]] | |||
| onset = | |||
| duration = | |||
| causes = | |||
| risks = | |||
| diagnosis = [[Clinical examination]], [[biopsy]] | |||
| differential = [[Erythema nodosum]], [[lipodermatosclerosis]], [[infectious panniculitis]] | |||
| treatment = [[Corticosteroids]], [[immunosuppressive therapy]] | |||
| medication = | |||
| prognosis = | |||
| frequency = | |||
}} | |||
'''Neutrophilic lobular panniculitis''' is a rare type of [[panniculitis]], a group of conditions characterized by inflammation of the [[subcutaneous fat]]. It is characterized by the presence of [[neutrophils]] in the lobules of the subcutaneous fat, hence the name. | '''Neutrophilic lobular panniculitis''' is a rare type of [[panniculitis]], a group of conditions characterized by inflammation of the [[subcutaneous fat]]. It is characterized by the presence of [[neutrophils]] in the lobules of the subcutaneous fat, hence the name. | ||
==Etiology== | ==Etiology== | ||
The exact cause of neutrophilic lobular panniculitis is unknown. However, it has been associated with various conditions such as [[autoimmune diseases]], [[infections]], and [[malignancies]]. Some cases have also been reported following the use of certain medications. | The exact cause of neutrophilic lobular panniculitis is unknown. However, it has been associated with various conditions such as [[autoimmune diseases]], [[infections]], and [[malignancies]]. Some cases have also been reported following the use of certain medications. | ||
==Clinical Presentation== | ==Clinical Presentation== | ||
Patients with neutrophilic lobular panniculitis typically present with tender, erythematous nodules or plaques on the skin. These lesions are most commonly found on the legs, but can occur anywhere on the body. Other symptoms may include fever, malaise, and weight loss. | Patients with neutrophilic lobular panniculitis typically present with tender, erythematous nodules or plaques on the skin. These lesions are most commonly found on the legs, but can occur anywhere on the body. Other symptoms may include fever, malaise, and weight loss. | ||
==Diagnosis== | ==Diagnosis== | ||
Diagnosis of neutrophilic lobular panniculitis is made based on clinical presentation and histopathological examination of a skin biopsy. The characteristic finding on histopathology is lobular inflammation of the subcutaneous fat with a predominance of neutrophils. | Diagnosis of neutrophilic lobular panniculitis is made based on clinical presentation and histopathological examination of a skin biopsy. The characteristic finding on histopathology is lobular inflammation of the subcutaneous fat with a predominance of neutrophils. | ||
==Treatment== | ==Treatment== | ||
Treatment of neutrophilic lobular panniculitis is aimed at reducing inflammation and managing any underlying conditions. This may involve the use of anti-inflammatory medications, immunosuppressive drugs, or antibiotics, depending on the individual patient's circumstances. | Treatment of neutrophilic lobular panniculitis is aimed at reducing inflammation and managing any underlying conditions. This may involve the use of anti-inflammatory medications, immunosuppressive drugs, or antibiotics, depending on the individual patient's circumstances. | ||
==Prognosis== | ==Prognosis== | ||
The prognosis of neutrophilic lobular panniculitis varies depending on the severity of the condition and any associated diseases. In some cases, the condition may resolve spontaneously, while in others, it may persist or recur. | The prognosis of neutrophilic lobular panniculitis varies depending on the severity of the condition and any associated diseases. In some cases, the condition may resolve spontaneously, while in others, it may persist or recur. | ||
==See Also== | ==See Also== | ||
* [[Panniculitis]] | * [[Panniculitis]] | ||
* [[Neutrophils]] | * [[Neutrophils]] | ||
* [[Subcutaneous fat]] | * [[Subcutaneous fat]] | ||
[[Category:Dermatology]] | [[Category:Dermatology]] | ||
[[Category:Inflammation]] | [[Category:Inflammation]] | ||
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{{Dermatology-stub}} | {{Dermatology-stub}} | ||
{{Medicine-stub}} | {{Medicine-stub}} | ||
{{No image}} | |||
Latest revision as of 01:21, 4 April 2025
| Neutrophilic lobular panniculitis | |
|---|---|
| Synonyms | |
| Pronounce | N/A |
| Specialty | Dermatology |
| Symptoms | Pain, tenderness, erythema, nodules |
| Complications | N/A |
| Onset | |
| Duration | |
| Types | N/A |
| Causes | |
| Risks | |
| Diagnosis | Clinical examination, biopsy |
| Differential diagnosis | Erythema nodosum, lipodermatosclerosis, infectious panniculitis |
| Prevention | N/A |
| Treatment | Corticosteroids, immunosuppressive therapy |
| Medication | |
| Prognosis | |
| Frequency | |
| Deaths | N/A |
Neutrophilic lobular panniculitis is a rare type of panniculitis, a group of conditions characterized by inflammation of the subcutaneous fat. It is characterized by the presence of neutrophils in the lobules of the subcutaneous fat, hence the name.
Etiology[edit]
The exact cause of neutrophilic lobular panniculitis is unknown. However, it has been associated with various conditions such as autoimmune diseases, infections, and malignancies. Some cases have also been reported following the use of certain medications.
Clinical Presentation[edit]
Patients with neutrophilic lobular panniculitis typically present with tender, erythematous nodules or plaques on the skin. These lesions are most commonly found on the legs, but can occur anywhere on the body. Other symptoms may include fever, malaise, and weight loss.
Diagnosis[edit]
Diagnosis of neutrophilic lobular panniculitis is made based on clinical presentation and histopathological examination of a skin biopsy. The characteristic finding on histopathology is lobular inflammation of the subcutaneous fat with a predominance of neutrophils.
Treatment[edit]
Treatment of neutrophilic lobular panniculitis is aimed at reducing inflammation and managing any underlying conditions. This may involve the use of anti-inflammatory medications, immunosuppressive drugs, or antibiotics, depending on the individual patient's circumstances.
Prognosis[edit]
The prognosis of neutrophilic lobular panniculitis varies depending on the severity of the condition and any associated diseases. In some cases, the condition may resolve spontaneously, while in others, it may persist or recur.
See Also[edit]
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