Diabetic angiopathy: Difference between revisions
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{{Infobox medical condition | |||
| name = Diabetic angiopathy | |||
| synonyms = Diabetic vascular disease | |||
| field = [[Endocrinology]], [[Cardiology]] | |||
| symptoms = [[Peripheral artery disease]], [[Retinopathy]], [[Nephropathy]] | |||
| complications = [[Heart attack]], [[Stroke]], [[Chronic kidney disease]] | |||
| onset = Typically after years of [[Diabetes mellitus]] | |||
| duration = Chronic | |||
| types = [[Microangiopathy]], [[Macroangiopathy]] | |||
| causes = [[Hyperglycemia]], [[Hypertension]], [[Dyslipidemia]] | |||
| risks = [[Smoking]], [[Obesity]], [[Sedentary lifestyle]] | |||
| diagnosis = [[Blood test]], [[Urinalysis]], [[Imaging studies]] | |||
| prevention = [[Blood sugar control]], [[Blood pressure management]], [[Lipid management]] | |||
| treatment = [[Lifestyle modification]], [[Medication]], [[Surgery]] | |||
| prognosis = Variable, depends on management | |||
| frequency = Common in individuals with [[Diabetes mellitus]] | |||
}} | |||
'''Diabetic angiopathy''' is a form of [[angiopathy]] associated with [[diabetic]] complications. While not exclusive, the two most common forms are [[diabetic retinopathy]] and [[diabetic nephropathy]], whose pathophysiologies are largely identical. | '''Diabetic angiopathy''' is a form of [[angiopathy]] associated with [[diabetic]] complications. While not exclusive, the two most common forms are [[diabetic retinopathy]] and [[diabetic nephropathy]], whose pathophysiologies are largely identical. | ||
== Overview == | == Overview == | ||
Diabetic angiopathy is a broad term that encompasses a range of vascular complications associated with [[diabetes mellitus]]. These complications are caused by changes in the blood vessels that can lead to damage and dysfunction in various parts of the body. | Diabetic angiopathy is a broad term that encompasses a range of vascular complications associated with [[diabetes mellitus]]. These complications are caused by changes in the blood vessels that can lead to damage and dysfunction in various parts of the body. | ||
== Pathophysiology == | == Pathophysiology == | ||
The pathophysiology of diabetic angiopathy is complex and multifactorial. It is primarily driven by prolonged exposure to hyperglycemia, which leads to a range of metabolic and vascular abnormalities. These include increased production of advanced glycation end products (AGEs), activation of the polyol pathway, increased expression of growth factors and cytokines, and endothelial dysfunction. | The pathophysiology of diabetic angiopathy is complex and multifactorial. It is primarily driven by prolonged exposure to hyperglycemia, which leads to a range of metabolic and vascular abnormalities. These include increased production of advanced glycation end products (AGEs), activation of the polyol pathway, increased expression of growth factors and cytokines, and endothelial dysfunction. | ||
== Clinical Manifestations == | == Clinical Manifestations == | ||
The clinical manifestations of diabetic angiopathy depend on the specific vessels involved and the organs they supply. The most common forms of diabetic angiopathy are: | The clinical manifestations of diabetic angiopathy depend on the specific vessels involved and the organs they supply. The most common forms of diabetic angiopathy are: | ||
* '''[[Diabetic retinopathy]]''': This is a leading cause of blindness in adults. It is characterized by progressive damage to the retina due to prolonged hyperglycemia. | * '''[[Diabetic retinopathy]]''': This is a leading cause of blindness in adults. It is characterized by progressive damage to the retina due to prolonged hyperglycemia. | ||
* '''[[Diabetic nephropathy]]''': This is a leading cause of end-stage renal disease. It is characterized by progressive damage to the kidneys due to prolonged hyperglycemia. | * '''[[Diabetic nephropathy]]''': This is a leading cause of end-stage renal disease. It is characterized by progressive damage to the kidneys due to prolonged hyperglycemia. | ||
== Treatment == | == Treatment == | ||
The primary goal of treatment for diabetic angiopathy is to manage the underlying diabetes and control blood glucose levels. This can help to slow the progression of vascular complications and reduce the risk of serious outcomes such as blindness and kidney failure. | The primary goal of treatment for diabetic angiopathy is to manage the underlying diabetes and control blood glucose levels. This can help to slow the progression of vascular complications and reduce the risk of serious outcomes such as blindness and kidney failure. | ||
== See Also == | == See Also == | ||
* [[Diabetes mellitus]] | * [[Diabetes mellitus]] | ||
* [[Diabetic retinopathy]] | * [[Diabetic retinopathy]] | ||
* [[Diabetic nephropathy]] | * [[Diabetic nephropathy]] | ||
* [[Angiopathy]] | * [[Angiopathy]] | ||
== References == | == References == | ||
<references /> | <references /> | ||
{{stub}} | {{stub}} | ||
[[Category:Diabetes]] | [[Category:Diabetes]] | ||
[[Category:Vascular diseases]] | [[Category:Vascular diseases]] | ||
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{{No image}} | {{No image}} | ||
{{No image}} | {{No image}} | ||
Latest revision as of 01:06, 4 April 2025
| Diabetic angiopathy | |
|---|---|
| Synonyms | Diabetic vascular disease |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Peripheral artery disease, Retinopathy, Nephropathy |
| Complications | Heart attack, Stroke, Chronic kidney disease |
| Onset | Typically after years of Diabetes mellitus |
| Duration | Chronic |
| Types | Microangiopathy, Macroangiopathy |
| Causes | Hyperglycemia, Hypertension, Dyslipidemia |
| Risks | Smoking, Obesity, Sedentary lifestyle |
| Diagnosis | Blood test, Urinalysis, Imaging studies |
| Differential diagnosis | N/A |
| Prevention | Blood sugar control, Blood pressure management, Lipid management |
| Treatment | Lifestyle modification, Medication, Surgery |
| Medication | N/A |
| Prognosis | Variable, depends on management |
| Frequency | Common in individuals with Diabetes mellitus |
| Deaths | N/A |
Diabetic angiopathy is a form of angiopathy associated with diabetic complications. While not exclusive, the two most common forms are diabetic retinopathy and diabetic nephropathy, whose pathophysiologies are largely identical.
Overview[edit]
Diabetic angiopathy is a broad term that encompasses a range of vascular complications associated with diabetes mellitus. These complications are caused by changes in the blood vessels that can lead to damage and dysfunction in various parts of the body.
Pathophysiology[edit]
The pathophysiology of diabetic angiopathy is complex and multifactorial. It is primarily driven by prolonged exposure to hyperglycemia, which leads to a range of metabolic and vascular abnormalities. These include increased production of advanced glycation end products (AGEs), activation of the polyol pathway, increased expression of growth factors and cytokines, and endothelial dysfunction.
Clinical Manifestations[edit]
The clinical manifestations of diabetic angiopathy depend on the specific vessels involved and the organs they supply. The most common forms of diabetic angiopathy are:
- Diabetic retinopathy: This is a leading cause of blindness in adults. It is characterized by progressive damage to the retina due to prolonged hyperglycemia.
- Diabetic nephropathy: This is a leading cause of end-stage renal disease. It is characterized by progressive damage to the kidneys due to prolonged hyperglycemia.
Treatment[edit]
The primary goal of treatment for diabetic angiopathy is to manage the underlying diabetes and control blood glucose levels. This can help to slow the progression of vascular complications and reduce the risk of serious outcomes such as blindness and kidney failure.
See Also[edit]
References[edit]
<references />
