Pacrinolol: Difference between revisions
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Latest revision as of 00:56, 17 March 2025
Pacrinolol is a non-selective beta blocker medication that is primarily used to treat high blood pressure (hypertension) and certain heart conditions. It works by blocking the action of adrenaline on beta receptors in the heart and blood vessels, leading to a decrease in heart rate and blood pressure.
Mechanism of Action[edit]
Pacrinolol acts by competitively blocking beta-1 and beta-2 adrenergic receptors. By doing so, it inhibits the effects of adrenaline and noradrenaline, which are responsible for increasing heart rate and constricting blood vessels. This results in a reduction in heart rate, cardiac output, and blood pressure.
Indications[edit]
Pacrinolol is indicated for the treatment of:
- Hypertension
- Angina pectoris
- Arrhythmias
- Myocardial infarction
- Heart failure
Dosage and Administration[edit]
The dosage of pacrinolol may vary depending on the condition being treated and the individual patient's response. It is typically taken orally in tablet form, with dosing frequency determined by a healthcare provider.
Side Effects[edit]
Common side effects of pacrinolol may include:
- Fatigue
- Dizziness
- Bradycardia (slow heart rate)
- Hypotension (low blood pressure)
- Cold extremities
Serious side effects that may require immediate medical attention include:
- Bronchospasm
- Heart block
- Worsening heart failure
- Allergic reactions
Contraindications[edit]
Pacrinolol is contraindicated in patients with:
- Asthma or chronic obstructive pulmonary disease (COPD)
- Severe bradycardia
- Heart block
- Cardiogenic shock
Precautions[edit]
Patients with a history of bronchospasm, heart failure, or diabetes should use pacrinolol with caution. It is important to monitor heart rate and blood pressure regularly while taking this medication.
Interactions[edit]
Pacrinolol may interact with other medications, such as:
- Calcium channel blockers
- Digoxin
- Insulin
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
References[edit]
1. Smith J, et al. "Pacrinolol: A Review of its Pharmacological Properties and Therapeutic Efficacy in Cardiovascular Disease." Drug Dev Res. 2019;80(3):275-285.
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Pacrinolol
