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| ==Pronunciation==
| | #Redirect [[Hepatitis A#Virology]] |
| HEH-puh-TY-tis ... VY-rus
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| [[File:Hepatitis A virus 01.jpg|alt=Hepatitis A virus|thumb|Hepatitis A virus]] | |
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| <youtube>
| | {{Italic title}} |
| title='''{{PAGENAME}}'''
| | {{Rcat shell|{{R from alternative scientific name|virus}}{{R to section}}{{R with possibilities}}{{R printworthy}}}} |
| movie_url=http://www.youtube.com/v/VSzn-B0w0fE
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| &rel=1
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| embed_source_url=http://www.youtube.com/v/VSzn-B0w0fE
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| &rel=1
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| wrap = yes
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| width=750
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| height=600
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| </youtube>
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| ==Summary==
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| * Hepatitis A virus is a virus that causes a serious liver disease.
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| * It is usually spread by contact with an infected person’s stool by eating food he or she has handled after not washing hands, but it can be spread in other ways.
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| * Symptoms of infection include jaundice, dark urine, and fever and other flu-like symptoms.
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| [[File:Hepatitis.gif|alt=Hepatitis|thumb|'''Hepatitis''']]
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| ==Definition==
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| * Hepatitis means [[inflammation]] of the [[liver]].
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| * When the liver is inflamed or damaged, its function can be affected.
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| * Heavy alcohol use, toxins, some medications, and certain medical conditions can cause hepatitis, but it is often caused by a virus.
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| * In the United States, the most common hepatitis viruses are hepatitis A virus, hepatitis B virus, and hepatitis C virus.
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| * Hepatitis A is a highly contagious, short-term liver infection caused by the hepatitis A virus.
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| * People who get hepatitis A may feel sick for a few weeks to several months but usually recover completely and do not have lasting liver damage. In rare cases, hepatitis A can cause liver failure and even death; this is more common in older people and in people with other serious health issues, such as chronic liver disease.
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| ==Incidence==
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| * In 2018, there were an estimated 24,900 hepatitis A cases were reported in the United States.
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| * Because some people don’t ever get diagnosed, the actual number of cases reported in that year is probably closer to 24,900.
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| * Since 2016, person-to-person outbreaks of hepatitis A have been occurring across the United States mainly among people who use injection drugs or are experiencing homelessness, resulting in more than 32,000 cases.
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| ==Risk factors==
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| * International travelers
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| * Men who have sex with men
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| * People who use injection or non-injection drugs (all those who use illegal drugs)
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| * People with occupational risk for exposure
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| * People who anticipate close personal contact with an international adoptee
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| * People experiencing homelessness
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| * People at increased risk for severe disease from HAV infection
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| * People with chronic liver disease
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| * People with human immunodeficiency virus infection
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| * For more information about assessing risk for hepatitis A, refer to Table 3 in Prevention of Hepatitis A Virus Infection in the United States: Recommendations of the Advisory Committee on Immunization Practices, 2020.
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| ==Signs and symptoms==
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| Among older children and adults, [[infection]] is typically symptomatic.
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| Symptoms usually occur abruptly and can include the following:
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| * [[Fever]]
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| * [[Fatigue]]
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| * [[Loss of appetite]]
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| * [[Nausea]]
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| * [[Vomiting]]
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| * [[Abdominal pain]]
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| * [[Dark urine]]
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| * [[Diarrhea]]
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| * [[Clay-colored stool]]
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| * [[Joint pain]]
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| * [[Jaundice]]
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| Most (70%) of infections in children younger than age 6 are not accompanied by symptoms.
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| When symptoms are present, young children typically do not have jaundice; most (>70%) older children and adults with HAV infection have this symptom.
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| <youtube>
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| title='''{{PAGENAME}}'''
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| movie_url=http://www.youtube.com/v/SB5BTwZ-Yd8
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| &rel=1
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| embed_source_url=http://www.youtube.com/v/SB5BTwZ-Yd8
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| &rel=1
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| wrap = yes
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| width=750
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| height=600
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| </youtube>
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| ==Incubation period==
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| * Symptoms of hepatitis A usually last less than 2 months, although 10%–15% of symptomatic persons have prolonged or relapsing disease for up to 6 months (9–13).
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| * The average incubation period for HAV is 28 days and ranges between 15–50 days.
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| ==Diagnosis==
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| Diagnosis is with a combination of history, physical examination including travel and food history, symptoms, ordering a blood tests for hepatitis A.
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| ==Treatment==
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| * To treat the symptoms of hepatitis A, rest, adequate nutrition, fluids and other supportive measures are recommended.
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| * Some people with severe symptoms will need medical care in a hospital.
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| ==Vaccination==
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| * Vaccination with the full, two-dose series of hepatitis A vaccine is the best way to prevent infection.
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| * Hepatitis A vaccine has been licensed in the United States for use in people 1 year of age and older.
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| The following people should be vaccinated against hepatitis A:
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| '''Children'''
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| * All children aged 12–23 months
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| * All children and adolescents 2–18 years of age who have not previously received hepatitis A vaccine (known as “catch up” vaccination)
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| * People at increased risk for hepatitis A
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| People at increased risk for severe disease from hepatitis A infection
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| '''Other people recommended for vaccination'''
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| * Pregnant women at risk for hepatitis A or risk for severe outcome from hepatitis A infection
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| * Any person who requests vaccination
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| * How is the hepatitis A vaccine given?
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| * There are two types of hepatitis A vaccine.
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| ===Vaccination schedule===
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| * The first type, the single-dose hepatitis A vaccine, is given as two shots, 6 months apart, and both shots are needed for long-term protection against hepatitis A.
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| * The other type is a combination vaccine that protects people against both hepatitis A and hepatitis B.
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| * The combination vaccine can be given to anyone 18 years of age and older and is given as three shots over 6 months.
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| * All three shots are needed for long-term protection for both hepatitis A and hepatitis B.
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| ===Immunoglobulins===
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| * Immune globulin can provide short-term protection against hepatitis A, both pre- and postexposure.
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| * Immune globulin must be administered within 2 weeks after exposure for maximum protection.
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| * Given that the virus is transmitted through the fecal-oral route, good hand hygiene—including handwashing after using the bathroom, changing diapers, and before preparing or eating food—is integral to hepatitis A prevention.
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| {{stub}}
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| {{Viral diseases}}
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| {{Consumer Food Safety}}
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| {{Taxonbar|from=Q24722353|from2=Q4112120}}
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| [[Category:Hepatitis A| ]]
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| [[Category:RTTID]]
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| [[Category:Picornaviridae]] | | [[Category:Picornaviridae]] |
| [[Category:Vaccine-preventable diseases]]
| | [[Category:Hepatitis A]] |
| [[Category:Hepatitis|+A]] | |