2-Oleoylglycerol: Difference between revisions

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{{Short description|A monoglyceride derived from oleic acid}}
{{DISPLAYTITLE:2-Oleoylglycerol}}
{{DISPLAYTITLE:2-Oleoylglycerol}}


'''2-Oleoylglycerol''' is a [[monoglyceride]] that is derived from [[oleic acid]], a common [[fatty acid]] found in various [[animal]] and [[plant]] sources. It is a type of [[glycerol]] ester where a single [[oleic acid]] molecule is esterified to the [[glycerol]] backbone.
== 2-Oleoylglycerol ==
[[File:2-Oleoylglycerol.svg|thumb|right|Structural formula of 2-Oleoylglycerol]]


==Structure and Properties==
'''2-Oleoylglycerol''' is a [[monoacylglycerol]], a type of [[glyceride]] that consists of a single [[fatty acid]] chain attached to a [[glycerol]] backbone. It is an important intermediate in the metabolism of [[lipids]] and plays a role in various biological processes.
2-Oleoylglycerol is characterized by its chemical structure, which consists of a glycerol molecule esterified at the second carbon position with an oleic acid moiety. This structure imparts certain physical and chemical properties to the compound, such as its solubility in organic solvents and its role in biological systems.


==Biological Role==
== Structure ==
In biological systems, 2-oleoylglycerol acts as a signaling molecule. It is involved in various [[metabolic]] pathways and can influence [[cell signaling]] processes. It is known to interact with certain [[receptors]] and enzymes, playing a role in the regulation of [[lipid metabolism]] and [[energy homeostasis]].
2-Oleoylglycerol is composed of a glycerol molecule esterified with a single oleic acid at the second carbon position. Oleic acid is a monounsaturated fatty acid with the chemical formula C__H__O_. The presence of the double bond in the oleic acid chain gives 2-Oleoylglycerol its characteristic properties.


==Synthesis==
== Biological Role ==
2-Oleoylglycerol can be synthesized through the enzymatic hydrolysis of [[triglycerides]] containing oleic acid. This process involves the action of [[lipases]] that selectively cleave the ester bonds in triglycerides, releasing 2-oleoylglycerol as one of the products.
In the body, 2-Oleoylglycerol is involved in the [[digestion]] and absorption of dietary fats. It is produced during the breakdown of [[triglycerides]] by the action of [[lipase]] enzymes. Once formed, 2-Oleoylglycerol can be further metabolized to release [[energy]] or be used in the synthesis of other lipids.


==Applications==
== Metabolism ==
Due to its role in biological systems, 2-oleoylglycerol is of interest in [[pharmaceutical]] and [[nutraceutical]] research. It is studied for its potential effects on [[inflammation]], [[metabolic disorders]], and other health-related conditions.
2-Oleoylglycerol is a key intermediate in the [[lipid metabolism]] pathway. It can be converted back into triglycerides for storage or further broken down into [[glycerol]] and [[free fatty acids]] for energy production. This process is regulated by various enzymes and is crucial for maintaining energy balance in the body.


==Related Compounds==
== Clinical Significance ==
2-Oleoylglycerol is related to other monoglycerides and glycerol esters, such as [[1-oleoylglycerol]] and [[2-arachidonoylglycerol]], which also play roles in biological signaling and metabolism.
Alterations in the levels of 2-Oleoylglycerol and other monoacylglycerols can be indicative of metabolic disorders. Understanding its role in lipid metabolism can help in the development of treatments for conditions such as [[obesity]] and [[diabetes]].


==Related pages==
== Related Compounds ==
* [[Monoglyceride]]
2-Oleoylglycerol is related to other monoacylglycerols such as 1-Oleoylglycerol and 3-Oleoylglycerol, which differ in the position of the oleic acid on the glycerol backbone. These compounds have similar but distinct roles in metabolism.
 
== Related Pages ==
* [[Glycerol]]
* [[Oleic acid]]
* [[Oleic acid]]
* [[Glycerol]]
* [[Triglyceride]]
* [[Lipid metabolism]]
* [[Lipid metabolism]]
* [[Monoacylglycerol]]


==Gallery==
[[Category:Lipids]]
<gallery>
[[Category:Biochemistry]]
File:2-Oleoylglycerol.svg|Chemical structure of 2-Oleoylglycerol
</gallery>
 
[[Category:Monoglycerides]]
[[Category:Fatty acid esters]]

Latest revision as of 11:34, 15 February 2025


2-Oleoylglycerol[edit]

Structural formula of 2-Oleoylglycerol

2-Oleoylglycerol is a monoacylglycerol, a type of glyceride that consists of a single fatty acid chain attached to a glycerol backbone. It is an important intermediate in the metabolism of lipids and plays a role in various biological processes.

Structure[edit]

2-Oleoylglycerol is composed of a glycerol molecule esterified with a single oleic acid at the second carbon position. Oleic acid is a monounsaturated fatty acid with the chemical formula C__H__O_. The presence of the double bond in the oleic acid chain gives 2-Oleoylglycerol its characteristic properties.

Biological Role[edit]

In the body, 2-Oleoylglycerol is involved in the digestion and absorption of dietary fats. It is produced during the breakdown of triglycerides by the action of lipase enzymes. Once formed, 2-Oleoylglycerol can be further metabolized to release energy or be used in the synthesis of other lipids.

Metabolism[edit]

2-Oleoylglycerol is a key intermediate in the lipid metabolism pathway. It can be converted back into triglycerides for storage or further broken down into glycerol and free fatty acids for energy production. This process is regulated by various enzymes and is crucial for maintaining energy balance in the body.

Clinical Significance[edit]

Alterations in the levels of 2-Oleoylglycerol and other monoacylglycerols can be indicative of metabolic disorders. Understanding its role in lipid metabolism can help in the development of treatments for conditions such as obesity and diabetes.

Related Compounds[edit]

2-Oleoylglycerol is related to other monoacylglycerols such as 1-Oleoylglycerol and 3-Oleoylglycerol, which differ in the position of the oleic acid on the glycerol backbone. These compounds have similar but distinct roles in metabolism.

Related Pages[edit]