Neurosporene: Difference between revisions

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'''Neurosporene''' is a type of [[carotenoid]], a class of organic pigments that are naturally occurring in the chloroplasts and chromoplasts of plants, algae, and photosynthetic bacteria. Neurosporene is a precursor in the biosynthesis of other carotenoids, including [[lycopene]], which is a key intermediate in the production of many other types of carotenoids.
{{DISPLAYTITLE:Neurosporene}}


== Structure and Properties ==
== Overview ==
[[File:Neurosporene.png|thumb|right|Chemical structure of Neurosporene]]
'''Neurosporene''' is a naturally occurring [[carotenoid]] that is an intermediate in the biosynthesis of other carotenoids such as [[lycopene]] and [[beta-carotene]]. It is a tetraterpene, meaning it is composed of eight [[isoprene]] units, and is part of the larger family of [[terpenoids]]. Neurosporene is characterized by its yellow-orange color and is found in various photosynthetic organisms, including some bacteria and plants.


Neurosporene is a tetraterpene, meaning it is composed of four [[terpene]] units. It has a linear structure with three conjugated double bonds, which gives it its characteristic color. The molecule is non-polar and lipophilic, meaning it is soluble in fats and oils but not in water.
== Chemical Structure ==
Neurosporene is a polyene, which means it contains multiple conjugated double bonds. This structure is responsible for its ability to absorb light in the visible spectrum, contributing to its color. The chemical formula of neurosporene is C<sub>40</sub>H<sub>56</sub>, and it is a linear molecule with alternating single and double bonds.


== Biosynthesis ==
== Biosynthesis ==
Neurosporene is synthesized in the [[carotenoid biosynthesis]] pathway. It is derived from [[phytoene]] through a series of desaturation reactions. The enzyme phytoene desaturase catalyzes the conversion of phytoene to [[zeta-carotene]], which is then converted to neurosporene by the action of zeta-carotene desaturase. Neurosporene can be further desaturated to form lycopene, a key precursor for other carotenoids.


The biosynthesis of neurosporene begins with the condensation of two molecules of [[geranylgeranyl pyrophosphate]] (GGPP), a common precursor in the biosynthesis of terpenes and terpenoids. This reaction is catalyzed by the enzyme [[phytoene synthase]], which removes the pyrophosphate groups and forms a carbon-carbon double bond to produce [[phytoene]]. Phytoene is then desaturated by the enzyme [[phytoene desaturase]] to produce neurosporene.
== Biological Role ==
In photosynthetic organisms, neurosporene plays a crucial role in the [[photosynthetic apparatus]]. It is involved in the protection of the [[photosystem]]s from photooxidative damage by quenching [[singlet oxygen]] and dissipating excess energy as heat. Neurosporene and other carotenoids are also involved in the assembly and stabilization of the photosynthetic complexes.


== Function ==
== Applications ==
 
Neurosporene, like other carotenoids, has potential applications in the food and pharmaceutical industries due to its antioxidant properties. It is being studied for its role in human health, particularly in the prevention of diseases related to oxidative stress.
As a carotenoid, neurosporene plays a crucial role in protecting cells from the damaging effects of reactive oxygen species, which are produced during photosynthesis. It does this by quenching singlet oxygen, a highly reactive form of oxygen, and by scavenging free radicals.
 
== See Also ==


== Related Pages ==
* [[Carotenoid]]
* [[Carotenoid]]
* [[Lycopene]]
* [[Lycopene]]
* [[Geranylgeranyl pyrophosphate]]
* [[Beta-carotene]]
* [[Phytoene synthase]]
* [[Photosynthesis]]
* [[Phytoene desaturase]]
* [[Antioxidant]]
 
== References ==
 
<references />


[[Category:Carotenoids]]
[[Category:Carotenoids]]
[[Category:Tetraterpenes]]
[[Category:Terpenoids]]
[[Category:Antioxidants]]
[[Category:Photosynthesis]]
{{pharmacology-stub}}

Latest revision as of 10:40, 15 February 2025


Overview[edit]

Chemical structure of Neurosporene

Neurosporene is a naturally occurring carotenoid that is an intermediate in the biosynthesis of other carotenoids such as lycopene and beta-carotene. It is a tetraterpene, meaning it is composed of eight isoprene units, and is part of the larger family of terpenoids. Neurosporene is characterized by its yellow-orange color and is found in various photosynthetic organisms, including some bacteria and plants.

Chemical Structure[edit]

Neurosporene is a polyene, which means it contains multiple conjugated double bonds. This structure is responsible for its ability to absorb light in the visible spectrum, contributing to its color. The chemical formula of neurosporene is C40H56, and it is a linear molecule with alternating single and double bonds.

Biosynthesis[edit]

Neurosporene is synthesized in the carotenoid biosynthesis pathway. It is derived from phytoene through a series of desaturation reactions. The enzyme phytoene desaturase catalyzes the conversion of phytoene to zeta-carotene, which is then converted to neurosporene by the action of zeta-carotene desaturase. Neurosporene can be further desaturated to form lycopene, a key precursor for other carotenoids.

Biological Role[edit]

In photosynthetic organisms, neurosporene plays a crucial role in the photosynthetic apparatus. It is involved in the protection of the photosystems from photooxidative damage by quenching singlet oxygen and dissipating excess energy as heat. Neurosporene and other carotenoids are also involved in the assembly and stabilization of the photosynthetic complexes.

Applications[edit]

Neurosporene, like other carotenoids, has potential applications in the food and pharmaceutical industries due to its antioxidant properties. It is being studied for its role in human health, particularly in the prevention of diseases related to oxidative stress.

Related Pages[edit]