CM156: Difference between revisions

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'''CM156‏‎''' is a synthetic compound that acts as an antagonist for the [[neurotransmitter]] receptors [[Sigma-1 receptor|sigma-1]] and [[Sigma-2 receptor|sigma-2]]. It was developed by researchers at the [[University of Southern California]] and has been studied for its potential applications in the treatment of [[neurodegenerative diseases]], [[psychiatric disorders]], and [[cancer]].
{{DISPLAYTITLE:CM156}}


== History ==
== Overview ==
[[File:CM156_Structure.svg|thumb|right|Chemical structure of CM156]]
CM156 is a synthetic compound that has been studied for its potential pharmacological effects. It is of interest in the field of medicinal chemistry due to its unique structure and potential therapeutic applications.


CM156 was first synthesized in the early 2000s by a team of researchers at the University of Southern California. The compound was developed as part of a larger project to create new sigma receptor antagonists with potential therapeutic applications.
== Chemical Structure ==
The chemical structure of CM156 is depicted in the image to the right. It is characterized by a complex arrangement of atoms that contribute to its biological activity. The structure includes several functional groups that are important for its interaction with biological targets.


== Structure and Mechanism of Action ==
== Pharmacology ==
CM156 has been investigated for its effects on various biological systems. It is believed to interact with specific receptors in the body, leading to potential therapeutic effects. The exact mechanism of action is still under study, but it is thought to involve modulation of neurotransmitter systems.


CM156 is a small, synthetic molecule that binds to both sigma-1 and sigma-2 receptors in the brain. These receptors are involved in a variety of physiological processes, including the regulation of [[neurotransmission]], [[cell proliferation]], and [[apoptosis]]. By blocking these receptors, CM156 can potentially modulate these processes and exert therapeutic effects.
== Potential Applications ==
Research into CM156 has suggested several potential applications, particularly in the treatment of neurological disorders. Its ability to modulate neurotransmitter systems makes it a candidate for further study in conditions such as anxiety, depression, and other mood disorders.


== Potential Therapeutic Applications ==
== Synthesis ==
The synthesis of CM156 involves several steps, starting from basic organic compounds. The process requires careful control of reaction conditions to ensure the correct formation of the desired structure. The synthesis is typically carried out in a laboratory setting by trained chemists.


=== Neurodegenerative Diseases ===
== Safety and Toxicology ==
As with any experimental compound, the safety and toxicology of CM156 are important considerations. Preliminary studies have been conducted to assess its safety profile, but more research is needed to fully understand its potential risks and benefits.


Research has suggested that sigma receptor antagonists like CM156 may have potential in the treatment of neurodegenerative diseases such as [[Alzheimer's disease]] and [[Parkinson's disease]]. These diseases are characterized by the progressive loss of neurons, and sigma receptor antagonists may help to protect these cells and slow the progression of the disease.
== Related pages ==
 
* [[Medicinal chemistry]]
=== Psychiatric Disorders ===
* [[Pharmacology]]
 
Sigma receptor antagonists have also been studied for their potential in the treatment of psychiatric disorders such as [[schizophrenia]] and [[depression]]. These disorders are thought to involve dysregulation of neurotransmission, and sigma receptor antagonists may help to normalize these processes.
 
=== Cancer ===
 
In addition to its potential neurological and psychiatric applications, CM156 has also been studied for its potential anti-cancer effects. Sigma receptors are overexpressed in many types of cancer cells, and blocking these receptors may help to inhibit the growth of these cells.
 
== See Also ==
 
* [[Sigma-1 receptor]]
* [[Sigma-2 receptor]]
* [[Neurotransmitter]]
* [[Neurotransmitter]]
* [[Neurodegenerative diseases]]
* [[Synthetic compound]]
* [[Psychiatric disorders]]
* [[Cancer]]


[[Category:Chemical compounds]]
[[Category:Pharmacology]]
[[Category:Neurotransmitter antagonists]]
[[Category:Medicinal chemistry]]
[[Category:Experimental drugs]]
{{Chem-stub}}
{{Medicine-stub}}

Latest revision as of 04:03, 13 February 2025


Overview[edit]

Chemical structure of CM156

CM156 is a synthetic compound that has been studied for its potential pharmacological effects. It is of interest in the field of medicinal chemistry due to its unique structure and potential therapeutic applications.

Chemical Structure[edit]

The chemical structure of CM156 is depicted in the image to the right. It is characterized by a complex arrangement of atoms that contribute to its biological activity. The structure includes several functional groups that are important for its interaction with biological targets.

Pharmacology[edit]

CM156 has been investigated for its effects on various biological systems. It is believed to interact with specific receptors in the body, leading to potential therapeutic effects. The exact mechanism of action is still under study, but it is thought to involve modulation of neurotransmitter systems.

Potential Applications[edit]

Research into CM156 has suggested several potential applications, particularly in the treatment of neurological disorders. Its ability to modulate neurotransmitter systems makes it a candidate for further study in conditions such as anxiety, depression, and other mood disorders.

Synthesis[edit]

The synthesis of CM156 involves several steps, starting from basic organic compounds. The process requires careful control of reaction conditions to ensure the correct formation of the desired structure. The synthesis is typically carried out in a laboratory setting by trained chemists.

Safety and Toxicology[edit]

As with any experimental compound, the safety and toxicology of CM156 are important considerations. Preliminary studies have been conducted to assess its safety profile, but more research is needed to fully understand its potential risks and benefits.

Related pages[edit]