5F-AB-PINACA: Difference between revisions

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{{Short description|Synthetic cannabinoid}}
== 5F-AB-PINACA ==
{{Drugbox
| verifiedfields = changed
| verifiedrevid = 477318752
| IUPAC_name = N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide
| image = 5F-AB-PINACA.svg
| width = 200px
| legal_status =  
| routes_of_administration =
| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
| excretion =
| CAS_number = 1800101-60-3
| PubChem = 86273332
| ChemSpiderID = 52085008
| UNII =
| KEGG =
| ChEMBL = 2105710
| C=18
| H=26
| F=1
| N=3
| O=2
| smiles = CC(C)(C(=O)N[C@@H](C)C(=O)N1C=C(C2=CC=CC=C21)CCCCCF)N
| StdInChI = 1S/C18H26FN3O2/c1-18(2,21)16(23)22-15(11-13(3)24)17(25)20-12-10-14-8-6-5-7-9-14-19-20/h5-10,12-13,15H,11,21H2,1-4H3,(H,22,23)
| StdInChIKey = ZJQJHFOOZKQXQF-UHFFFAOYSA-N
}}


'''5F-AB-PINACA''' is a synthetic [[cannabinoid]] that has been used as an active ingredient in synthetic [[cannabis]] products. It is a potent agonist of the [[CB1 receptor]] and [[CB2 receptor]], which are part of the [[endocannabinoid system]].
[[File:5F-AB-PINACA.svg|thumb|right|Chemical structure of 5F-AB-PINACA]]


==Chemical structure and properties==
'''5F-AB-PINACA''' is a synthetic cannabinoid that has been used as a designer drug. It is a potent agonist of the [[cannabinoid receptor]]s, specifically the [[CB1 receptor]] and [[CB2 receptor]].
5F-AB-PINACA is chemically classified as an indazole-based synthetic cannabinoid. Its IUPAC name is N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide. The compound has a molecular formula of C<sub>18</sub>H<sub>26</sub>FN<sub>3</sub>O<sub>2</sub> and a molecular weight of 335.42 g/mol.


The structure of 5F-AB-PINACA includes a fluorinated pentyl chain, which is a common feature in many synthetic cannabinoids, contributing to its high potency and affinity for cannabinoid receptors.
=== Chemical Structure ===
5F-AB-PINACA is chemically classified as an indazole-based synthetic cannabinoid. Its structure includes a 5-fluoropentyl chain, which is a common feature in many synthetic cannabinoids, contributing to its high potency and affinity for cannabinoid receptors.


==Pharmacology==
=== Pharmacology ===
5F-AB-PINACA acts as a full agonist at the [[CB1 receptor]] and [[CB2 receptor]], with a higher affinity for the CB1 receptor. This interaction with the endocannabinoid system results in psychoactive effects similar to those of [[tetrahydrocannabinol]] (THC), the primary psychoactive component of cannabis.
5F-AB-PINACA acts as a full agonist at the CB1 and CB2 receptors, which are part of the [[endocannabinoid system]]. This system is involved in regulating various physiological processes, including mood, memory, and pain sensation. The activation of these receptors by 5F-AB-PINACA can lead to psychoactive effects similar to those of [[tetrahydrocannabinol]] (THC), the active component of [[cannabis]].


The compound's high potency and efficacy at cannabinoid receptors can lead to significant psychoactive effects, which may include euphoria, altered perception, and relaxation. However, it can also cause adverse effects such as anxiety, paranoia, and tachycardia.
=== Effects ===
The effects of 5F-AB-PINACA can include euphoria, relaxation, altered perception, and increased appetite. However, due to its high potency, it can also cause adverse effects such as anxiety, paranoia, tachycardia, and in severe cases, [[psychosis]] or [[seizures]].


==Legal status==
=== Legal Status ===
The legal status of 5F-AB-PINACA varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of accepted medical use. Regulatory agencies have placed it under various schedules to restrict its distribution and use.
Due to its potential for abuse and lack of medical use, 5F-AB-PINACA has been classified as a controlled substance in many countries. It is often included in the list of substances banned under synthetic drug laws.


==Health effects and safety==
=== Synthesis ===
The use of 5F-AB-PINACA has been associated with numerous adverse health effects. These can include acute intoxication, cardiovascular complications, and neuropsychiatric symptoms. Due to its potency, there is a significant risk of overdose, which can lead to severe health consequences or death.
The synthesis of 5F-AB-PINACA involves the reaction of an indazole core with a fluorinated alkyl chain. This process requires specialized knowledge in organic chemistry and access to specific reagents and equipment.


==Related pages==
=== Health Risks ===
The use of 5F-AB-PINACA has been associated with numerous health risks, including acute intoxication and long-term psychological effects. Users may experience severe withdrawal symptoms, and there is a risk of developing [[substance use disorder]].
 
== Related Pages ==
* [[Synthetic cannabinoids]]
* [[Synthetic cannabinoids]]
* [[Cannabinoid receptor]]
* [[Cannabinoid receptor]]
* [[Endocannabinoid system]]
* [[Endocannabinoid system]]
* [[Tetrahydrocannabinol]]
* [[Designer drug]]


[[Category:Synthetic cannabinoids]]
[[Category:Synthetic cannabinoids]]
[[Category:Designer drugs]]
[[Category:Indazolecarboxamides]]

Latest revision as of 03:36, 13 February 2025

5F-AB-PINACA[edit]

Chemical structure of 5F-AB-PINACA

5F-AB-PINACA is a synthetic cannabinoid that has been used as a designer drug. It is a potent agonist of the cannabinoid receptors, specifically the CB1 receptor and CB2 receptor.

Chemical Structure[edit]

5F-AB-PINACA is chemically classified as an indazole-based synthetic cannabinoid. Its structure includes a 5-fluoropentyl chain, which is a common feature in many synthetic cannabinoids, contributing to its high potency and affinity for cannabinoid receptors.

Pharmacology[edit]

5F-AB-PINACA acts as a full agonist at the CB1 and CB2 receptors, which are part of the endocannabinoid system. This system is involved in regulating various physiological processes, including mood, memory, and pain sensation. The activation of these receptors by 5F-AB-PINACA can lead to psychoactive effects similar to those of tetrahydrocannabinol (THC), the active component of cannabis.

Effects[edit]

The effects of 5F-AB-PINACA can include euphoria, relaxation, altered perception, and increased appetite. However, due to its high potency, it can also cause adverse effects such as anxiety, paranoia, tachycardia, and in severe cases, psychosis or seizures.

Legal Status[edit]

Due to its potential for abuse and lack of medical use, 5F-AB-PINACA has been classified as a controlled substance in many countries. It is often included in the list of substances banned under synthetic drug laws.

Synthesis[edit]

The synthesis of 5F-AB-PINACA involves the reaction of an indazole core with a fluorinated alkyl chain. This process requires specialized knowledge in organic chemistry and access to specific reagents and equipment.

Health Risks[edit]

The use of 5F-AB-PINACA has been associated with numerous health risks, including acute intoxication and long-term psychological effects. Users may experience severe withdrawal symptoms, and there is a risk of developing substance use disorder.

Related Pages[edit]