Tylvalosin: Difference between revisions
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== Tylvalosin == | == Tylvalosin == | ||
[[File:Tylvalosin.svg|thumb|Chemical structure of Tylvalosin]] | [[File:Tylvalosin.svg|thumb|right|Chemical structure of Tylvalosin]] | ||
'''Tylvalosin''' is a macrolide antibiotic used primarily in veterinary medicine. It is a derivative of [[tylosin]], which is another macrolide antibiotic. Tylvalosin is known for its effectiveness against a variety of bacterial infections in animals, particularly in swine and poultry. | |||
Tylvalosin is a derivative of [[tylosin]], another macrolide antibiotic. | |||
== Mechanism of Action == | |||
Tylvalosin works by inhibiting bacterial protein synthesis. It binds to the 50S subunit of the bacterial ribosome, thereby preventing the translocation of peptides. This action is similar to other macrolides, which makes it effective against Gram-positive bacteria and some Gram-negative bacteria. | |||
== Uses in Veterinary Medicine == | == Uses in Veterinary Medicine == | ||
== | Tylvalosin is primarily used in the treatment and prevention of respiratory and enteric diseases in animals. It is particularly effective against diseases caused by [[Mycoplasma]] species, which are common pathogens in swine and poultry. | ||
=== Swine === | |||
In swine, tylvalosin is used to treat and prevent [[porcine proliferative enteropathy]], also known as ileitis, which is caused by the bacterium ''[[Lawsonia intracellularis]]''. It is also used to control [[swine respiratory disease]] (SRD) caused by ''[[Mycoplasma hyopneumoniae]]'' and other bacteria. | |||
=== Poultry === | |||
In poultry, tylvalosin is used to treat [[avian mycoplasmosis]], which is caused by ''[[Mycoplasma gallisepticum]]'' and ''[[Mycoplasma synoviae]]''. These infections can lead to respiratory issues and reduced egg production in birds. | |||
== Administration and Dosage == | |||
Tylvalosin is typically administered orally, often mixed with feed or water. The dosage and duration of treatment depend on the species being treated, the severity of the infection, and the specific condition being addressed. | |||
== Safety and | == Safety and Side Effects == | ||
Tylvalosin is generally considered safe when used as directed. However, as with all antibiotics, there is a risk of developing antibiotic resistance. It is important to follow veterinary guidance to minimize this risk. Common side effects may include gastrointestinal disturbances, but these are usually mild and transient. | |||
== Related Pages == | == Related Pages == | ||
* [[Macrolide antibiotics]] | * [[Macrolide antibiotics]] | ||
* [[Tylosin]] | * [[Tylosin]] | ||
* [[ | * [[Mycoplasma]] | ||
* [[Veterinary medicine]] | |||
[[Category:Antibiotics]] | [[Category:Antibiotics]] | ||
[[Category:Veterinary drugs]] | [[Category:Veterinary drugs]] | ||
Latest revision as of 03:31, 13 February 2025
Tylvalosin[edit]
Tylvalosin is a macrolide antibiotic used primarily in veterinary medicine. It is a derivative of tylosin, which is another macrolide antibiotic. Tylvalosin is known for its effectiveness against a variety of bacterial infections in animals, particularly in swine and poultry.
Mechanism of Action[edit]
Tylvalosin works by inhibiting bacterial protein synthesis. It binds to the 50S subunit of the bacterial ribosome, thereby preventing the translocation of peptides. This action is similar to other macrolides, which makes it effective against Gram-positive bacteria and some Gram-negative bacteria.
Uses in Veterinary Medicine[edit]
Tylvalosin is primarily used in the treatment and prevention of respiratory and enteric diseases in animals. It is particularly effective against diseases caused by Mycoplasma species, which are common pathogens in swine and poultry.
Swine[edit]
In swine, tylvalosin is used to treat and prevent porcine proliferative enteropathy, also known as ileitis, which is caused by the bacterium Lawsonia intracellularis. It is also used to control swine respiratory disease (SRD) caused by Mycoplasma hyopneumoniae and other bacteria.
Poultry[edit]
In poultry, tylvalosin is used to treat avian mycoplasmosis, which is caused by Mycoplasma gallisepticum and Mycoplasma synoviae. These infections can lead to respiratory issues and reduced egg production in birds.
Administration and Dosage[edit]
Tylvalosin is typically administered orally, often mixed with feed or water. The dosage and duration of treatment depend on the species being treated, the severity of the infection, and the specific condition being addressed.
Safety and Side Effects[edit]
Tylvalosin is generally considered safe when used as directed. However, as with all antibiotics, there is a risk of developing antibiotic resistance. It is important to follow veterinary guidance to minimize this risk. Common side effects may include gastrointestinal disturbances, but these are usually mild and transient.
