Artificial skin: Difference between revisions

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'''Artificial Skin''' is a synthetic (lab produced) substitute for human skin, primarily used in the treatment of severe burns and other skin injuries. It is also known as [[skin substitute]] or [[skin graft]].
== Arabidopsis thaliana ==


== History ==
'''''Arabidopsis thaliana''''', commonly known as thale cress, is a small flowering plant native to Eurasia. It is a member of the [[Brassicaceae]] family, which also includes species such as [[cabbage]] and [[mustard]]. ''Arabidopsis thaliana'' is widely used as a model organism in plant biology and genetics due to its small genome, short life cycle, and ease of cultivation.
The concept of artificial skin has been around since the 1980s, with the first successful implementation of an artificial skin in a burn patient occurring in 1981. The development of artificial skin has been driven by the need to find an effective alternative to [[autografts]], which are grafts of skin from the patient's own body, and [[allografts]], which are grafts of skin from a donor.


== Composition ==
=== Description ===
Artificial skin is typically composed of a [[biomaterial]] matrix that supports the growth of [[dermal]] and [[epidermal]] cells. The matrix is often made of [[collagen]], a protein that provides a scaffold for cell growth. The dermal and epidermal cells are usually derived from human skin cells, although other sources such as stem cells are also being explored.
''Arabidopsis thaliana'' is a small, herbaceous plant that typically grows to a height of 20–25 cm. It has a rosette of basal leaves and produces a flowering stem with small, white flowers. The plant is an annual, completing its life cycle in about six weeks under optimal conditions.


== Uses ==
=== Genome ===
Artificial skin is primarily used in the treatment of severe burns, where it can help to promote healing and reduce the risk of infection. It is also used in the treatment of chronic wounds, such as [[diabetic ulcers]], and in reconstructive surgery. In addition to these medical applications, artificial skin is also used in research and testing, for example in the testing of cosmetics and other skin products.
The genome of ''Arabidopsis thaliana'' was the first plant genome to be sequenced, completed in 2000. It consists of five chromosomes and approximately 135 million base pairs, encoding around 27,000 genes. This relatively small genome size makes it an ideal model for genetic studies.


== Challenges and Future Directions ==
=== Research Applications ===
While artificial skin has many benefits, there are also challenges associated with its use. These include the high cost of production, the risk of immune rejection, and the difficulty of achieving a natural appearance and function. Future research in the field of artificial skin is focused on addressing these challenges, for example through the development of more cost-effective production methods, the use of immune-compatible materials, and the incorporation of hair follicles and sweat glands to achieve a more natural appearance and function.
''Arabidopsis thaliana'' is extensively used in research to study plant development, genetics, and physiology. It has been instrumental in understanding the [[ABC model of flower development]], [[phototropism]], and [[plant hormone]] signaling pathways. The plant's genetic tractability allows for the creation of mutants to study gene function.


== See Also ==
=== Mutants ===
* [[Skin graft]]
Mutants of ''Arabidopsis thaliana'' have been used to study various biological processes. For example, mutants with altered flower development have provided insights into the genetic control of floral organ identity. Other mutants have been used to study responses to environmental stresses such as drought and salinity.
* [[Biomaterial]]
* [[Collagen]]
* [[Dermal cells]]
* [[Epidermal cells]]


[[Category:Medicine]]
=== Ecological and Evolutionary Studies ===
[[Category:Biotechnology]]
In addition to laboratory research, ''Arabidopsis thaliana'' is used in ecological and evolutionary studies. Its natural populations exhibit a wide range of genetic diversity, making it a valuable system for studying adaptation and natural selection.
[[Category:Medical treatments]]
 
{{Medicine-stub}}
== Related pages ==
{{Biotechnology-stub}}
* [[Brassicaceae]]
* [[Model organism]]
* [[Plant genetics]]
* [[Genomics]]
 
== Gallery ==
<gallery>
File:194_Arabidopsis_thaliana,_Turritis_glabra.jpg|''Arabidopsis thaliana'' in its natural habitat
File:Müürlooga_(Arabidopsis_thaliana)_lehekarv_(trihhoom)_311_0804.JPG|Trichomes on ''Arabidopsis thaliana'' leaf
File:Arabidopsis_mutants.jpg|Mutants of ''Arabidopsis thaliana''
File:Plastomap_of_Arabidopsis_thaliana.svg|Plastid map of ''Arabidopsis thaliana''
File:ABC_flower_development.svg|ABC model of flower development
File:ArabidopsisPlantPathology.jpg|''Arabidopsis thaliana'' in plant pathology research
File:Microbial_consortia_naturally_formed_on_the_roots_of_Arabidopsis_thaliana.webp|Microbial consortia on ''Arabidopsis thaliana'' roots
</gallery>
 
[[Category:Model organisms]]
[[Category:Brassicaceae]]
[[Category:Plant genetics]]

Latest revision as of 18:39, 11 February 2025

Arabidopsis thaliana[edit]

Arabidopsis thaliana, commonly known as thale cress, is a small flowering plant native to Eurasia. It is a member of the Brassicaceae family, which also includes species such as cabbage and mustard. Arabidopsis thaliana is widely used as a model organism in plant biology and genetics due to its small genome, short life cycle, and ease of cultivation.

Description[edit]

Arabidopsis thaliana is a small, herbaceous plant that typically grows to a height of 20–25 cm. It has a rosette of basal leaves and produces a flowering stem with small, white flowers. The plant is an annual, completing its life cycle in about six weeks under optimal conditions.

Genome[edit]

The genome of Arabidopsis thaliana was the first plant genome to be sequenced, completed in 2000. It consists of five chromosomes and approximately 135 million base pairs, encoding around 27,000 genes. This relatively small genome size makes it an ideal model for genetic studies.

Research Applications[edit]

Arabidopsis thaliana is extensively used in research to study plant development, genetics, and physiology. It has been instrumental in understanding the ABC model of flower development, phototropism, and plant hormone signaling pathways. The plant's genetic tractability allows for the creation of mutants to study gene function.

Mutants[edit]

Mutants of Arabidopsis thaliana have been used to study various biological processes. For example, mutants with altered flower development have provided insights into the genetic control of floral organ identity. Other mutants have been used to study responses to environmental stresses such as drought and salinity.

Ecological and Evolutionary Studies[edit]

In addition to laboratory research, Arabidopsis thaliana is used in ecological and evolutionary studies. Its natural populations exhibit a wide range of genetic diversity, making it a valuable system for studying adaptation and natural selection.

Related pages[edit]

Gallery[edit]