https://wikimd.org/index.php?action=history&feed=atom&title=Zinc_finger 2026-04-27T17:43:56Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.org/index.php?title=Zinc_finger&diff=6321898&oldid=prev 2025-02-18T11:09:06Z

<p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 11:09, 18 February 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l23">Line 23:</td> <td colspan="2" class="diff-lineno">Line 23:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; 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font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">File:Zinc_finger_rendered.png|Zinc finger rendered</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">File:Zinc_finger_DNA_complex.png|Zinc finger DNA complex</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">File:PDB_1zaa_EBI.jpg|Zinc finger</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">File:PDB_1ncp_EBI.jpg|Zinc finger</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">File:PDB_1pft_EBI.jpg|Zinc finger</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">File:PDB_1d66_EBI.jpg|Zinc finger</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">File:PDB_1pxe_EBI.jpg|Zinc finger</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">&lt;/gallery&gt;</ins></div></td></tr> </table>

Prab https://wikimd.org/index.php?title=Zinc_finger&diff=5283509&oldid=prev 2024-02-25T08:33:51Z

<p>CSV import</p> <p><b>New page</b></p><div>&#039;&#039;&#039;Zinc finger&#039;&#039;&#039; is a small [[protein]] structure that is characterized by the coordination of one or more [[zinc]] ions in order to stabilize the fold. Originally coined to describe the finger-like appearance of a hypothesized structure from [[X-ray diffraction]], the term now refers to a wide variety of differing protein structures.<br /> <br /> ==Structure==<br /> Zinc fingers form parts of some [[transcription factor]]s, which are proteins that recognize [[DNA]] sequences. They do this by creating a binding site where the zinc ion and the amino acids from the zinc finger protein interact with the DNA molecule. This interaction allows the transcription factor to bind to the DNA sequence and regulate the transcription of DNA to [[mRNA]].<br /> <br /> ==Types==<br /> There are many types of zinc fingers. The classical zinc finger, also known as the Cys2His2 (C2H2) zinc finger, is the most commonly found type in the human genome. Other types include the Cys4, Cys6, and Cys2HisCys zinc fingers. Each type has a unique structure and function.<br /> <br /> ==Function==<br /> Zinc fingers play crucial roles in various biological processes. They are involved in [[gene regulation]], [[DNA repair]], [[lipid binding]], and [[protein folding]]. They can also act as [[enzyme]]s, performing reactions that involve the transfer of functional groups to other molecules.<br /> <br /> ==Clinical significance==<br /> Mutations in zinc finger proteins have been associated with a number of diseases, including some types of [[cancer]], [[autoimmune diseases]], and [[neurodegenerative diseases]]. Understanding the structure and function of zinc fingers can therefore provide important insights into the mechanisms of these diseases.<br /> <br /> ==See also==<br /> * [[Transcription factor]]<br /> * [[DNA repair]]<br /> * [[Protein structure]]<br /> <br /> [[Category:Protein domains]]<br /> [[Category:DNA-binding proteins]]<br /> [[Category:Zinc proteins]]<br /> <br /> {{stub}}</div>

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