https://wikimd.org/index.php?action=history&feed=atom&title=ZM-241%2C385ZM-241,385 - Revision history2026-04-29T08:40:05ZRevision history for this page on the wikiMediaWiki 1.44.2https://wikimd.org/index.php?title=ZM-241,385&diff=5805792&oldid=prevPrab: CSV import2024-05-22T15:30:50Z<p>CSV import</p>
<p><b>New page</b></p><div>[[File:ZM-241,385_Structure.svg|thumb|ZM-241,385_Structure.svg]] '''ZM-241,385''' is a potent and selective [[adenosine receptor]] antagonist, specifically targeting the [[adenosine A2A receptor]]. It is widely used in [[pharmacological research]] to study the role of adenosine receptors in various physiological and pathological processes.<br />
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==Chemical Properties==<br />
ZM-241,385 is a synthetic compound with a complex chemical structure. It is known for its high affinity and selectivity towards the adenosine A2A receptor, making it a valuable tool in [[neuroscience]] and [[cardiovascular research]].<br />
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==Mechanism of Action==<br />
ZM-241,385 functions by binding to the adenosine A2A receptor, thereby inhibiting the action of [[adenosine]], a [[neurotransmitter]] that plays a crucial role in regulating [[neurotransmission]], [[vasodilation]], and [[immune response]]. By blocking this receptor, ZM-241,385 can modulate various physiological responses, making it useful in studying conditions such as [[Parkinson's disease]], [[ischemia]], and [[inflammation]].<br />
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==Applications in Research==<br />
===Neuroscience===<br />
In [[neuroscience]], ZM-241,385 is used to investigate the role of adenosine A2A receptors in [[neurodegenerative diseases]] like [[Parkinson's disease]]. Studies have shown that antagonism of these receptors can have neuroprotective effects, potentially offering therapeutic benefits.<br />
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===Cardiovascular Research===<br />
ZM-241,385 is also employed in [[cardiovascular research]] to explore its effects on [[vasodilation]] and [[myocardial ischemia]]. By blocking the adenosine A2A receptor, researchers can better understand the mechanisms underlying [[cardiovascular diseases]] and develop new therapeutic strategies.<br />
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===Immunology===<br />
In the field of [[immunology]], ZM-241,385 is used to study the role of adenosine A2A receptors in modulating the [[immune response]]. This research is crucial for developing treatments for [[inflammatory diseases]] and [[autoimmune disorders]].<br />
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==Safety and Handling==<br />
As with any research chemical, proper safety protocols must be followed when handling ZM-241,385. It should be used in a controlled laboratory environment, and appropriate [[personal protective equipment]] (PPE) should be worn to prevent exposure.<br />
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==See Also==<br />
* [[Adenosine receptor]]<br />
* [[Neurotransmitter]]<br />
* [[Parkinson's disease]]<br />
* [[Ischemia]]<br />
* [[Inflammation]]<br />
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==References==<br />
{{Reflist}}<br />
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==External Links==<br />
{{No external links}}<br />
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[[Category:Pharmacology]]<br />
[[Category:Neuroscience]]<br />
[[Category:Cardiovascular research]]<br />
[[Category:Immunology]]<br />
[[Category:Research chemicals]]<br />
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